Get Me Out of Here; It's Too Crowded (PowerPoint)

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Identifier walsh_2008_s2_c3_pp
Title Get Me Out of Here; It's Too Crowded (PowerPoint)
Creator Wang-Ko, Melissa
Subject Leukemia, Promyelocytic, Acute; Granulocyte Precursor Cells; Optic Neuritis; Pupil Disorders; Scotoma; Multiple Sclerosis
Presenting Symptom Headache; Deteriorating vision
History A 54-year old female with a 6-week history of progressive deteriorating vision OU, headache and pain associating with eye movements. Previous history significant for multiple sclerosis.
Clinical VA: CF at 1' OD, 20/60 OS declining to BLP OD, CF at 5' OS; RAPD OD
Neuroimaging MRI
Pathology Leukemic cells in perineural space of optic nerve
Disease/Diagnosis Leukemic optic neuropathy in acute promyelocytic leukemia
Treatment Chemotherapy; XRT
References 1. Liso V, Specchia G, Pogliani EM, Palumbo G, Mininni D, Rossi V, Teruzzi E,Mestice A, Coppi MR, Biondi A. Extramedullary involvement in patients with acute promyelocytic leukemia: a report of seven cases.Cancer 15;83(8):1522-8, 1988. 2. Kaikov Y Optic nerve head infiltration in acute leukemia in children: an indication for emergency optic nerve radiation therapy.Med Pediatr Oncol.26(2):101-4: 1996. 3. Brown DM, Kimura AE, Ossoinig KC, Weiner GJ. Acute promyelocytic infiltration of the optic nerve treated by oral trans-retinoic acid. Ophthalmology;99(9): 1463-7: 1992. 4. Evans GD, Grimwade DJ. Extramedullary disease in acute promyelocytic leukemia. Leuk Lymphoma 33(3-4): 219-229: 1999. 5. Ledda A, Coacci G, Spinicci G et al. Two new cases of promyelocytic leukemia following mitoxantrone treatment in patients with multiple sclerosis. Leukemia 20; 2217-18: 2006. 6. Nikaido H, Mishima H, Ono H, Choshi K, Dohy H. Leukemic involvement of the optic nerve. Am J Ophthalmol 15;105(3):294-8: 1988.
Relation is Part of Session 2, Case 3, Walsh Session, NANOS 2008
Contributor Primary Wang-Ko, Melissa
Contributor Secondary Tamhankar, Madhura; Volpe, Nicholas; Galetta, Steven; Porter, David; McGrath, Cindy
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2008-03-09
Type Text
Format application/pdf
Source 40th Annual Frank Walsh Society Meeting
Rights Management Copyright 2002. For further information regarding the rights to this collection, please visit:
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Collection Neuro-ophthalmology Virtual Education Library: NOVEL
Language eng
ARK ark:/87278/s6xp77qr
Setname ehsl_novel_fbw
ID 178214
Reference URL