| Identifier |
20200309_nanos_sciplatform1_02-pdf |
| Title |
Resveratrol Nanoparticles Are Neuroprotective in Experimental, Optic Neuritis (PDF) |
| Creator |
Ehtesham Shamsher; Reas Khan; Kimberly Dine; Vy Luong; Benjamin Davis; Keirnan Willett; Satyanarayana Somavarapu; M. Francesca Cordeiro; Kenneth Shindler |
| Affiliation |
(ES) University College London, London, United Kingdom of Great Britain and Northern Ireland; (RK) (KD) (KW) (KS) Scheie Eye Institute, University of Pennsylvania, Philadelphia; (BD) (MFC) Institute of Ophthalmology, University College London, London, United Kingdom of Great Britain and Northern Ireland; (SS) School of Pharmacy, University College London, London, United Kingdom of Great Britain and Northern Ireland |
| Subject |
Neuro-ophthalmology & Systemic Disease (eg. MS, MG, Thyroid); Demylinating Disease |
| Description |
Optic neuritis is the most common clinical manifestation of multiple sclerosis. Axonal damage and neuronal loss lead to permanent neurological disability in patients and its animal model, experimental autoimmune encephalomyelitis (EAE). Presently, treatments of this condition aim to reduce inflammation without showing any neuroprotection. Resveratrol is a natural polyphenol found in red wine with neuroprotective effects but poor solubility in water. Thus, a novel nanoparticle formulation of resveratrol was developed and assessed in a mouse model of EAE. |
| Date |
2020-03 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
2020 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS Annual Meeting 2020: Scientific Platform Session I |
| Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2020. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6sn5km6 |
| Setname |
ehsl_novel_nam |
| ID |
1543326 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6sn5km6 |
