Characterization of Leber's Hereditary Optic Neuropathy Patients Treated with Idebenone

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Identifier 20150224_nanos_posters_008
Title Characterization of Leber's Hereditary Optic Neuropathy Patients Treated with Idebenone
Creator Jasdeep S. Chahal; Michael J. Ammar; Rustum Karanjia; Alfredo Sadun
Affiliation (JSC) (MJA) USC/Keck School of Medicine, Los Angeles, CA; (RK) (AS) UCLA/Doheny Eye Institute, Los Angeles, CA
Subject Genetic Disease; Optic Neuropathy; Visual Fields; Diagnostic Tests
Description There is conflicting data regarding the efficacy of Idebenone as a treatment for Leber's Hereditary Optic Neuropathy (LHON) [1, 2]. Klopstock et al. did not find a significant increase in recovery of BCVA in patients treated with Idebenone while Carelli et al. did (from off-chart (<20/400) to on-chart), specifically in the mutation 11778. Our aim was to determine if there was an improvement in vision even if patients stayed off-chart.
Date 2015-02-24
Language eng
Format application/pdf
Type Text
Source 2015 North American Neuro-Ophthalmology Society Annual Meeting
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2015. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6rz2jxg
Setname ehsl_novel_nam
ID 184907
Reference URL https://collections.lib.utah.edu/ark:/87278/s6rz2jxg