Title |
Detail of lamellar body (surfactant) and type I alveolar cell in lung (rat) |
Creator |
Poels, Lambert G. |
Contributor |
Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen |
Date |
2006-09-28 |
Subject |
Pneumocyte I ; Pneumocyte II; Alveolar cells; Tubular myelin |
Description |
Electron microscopy. After fixation the extracellular lining of surfactant (phosphatidylcholine, phosphoglycerol, cholesterol and proteins) will often be present as free packed lamellae in the alveolar space (4). This so-called tubular myelin is observed as stacks (5) of lipid crystals and aqueous layers of proteins and proteoglycans (crystalline phase of a polar lipid-water system). (1) point to type I alveolar cell, (2) indicates common basal lamina of alveolar cell and endothelium (3) of capillary (C). Note the transport vesicles (*) in both (1) and (3). (↔) is the air-blood barrier is the so-called thin-walled area. Thin-walled areas are most favourable to gas exchange and alternate with thick-walled areas (not shown here) consisting of supporting fibers, extracellular matrix and cells of the alveolar framework that separate the alveolar epithelium from the capillaries. |
Subtype |
Image |
Format |
image/jpeg |
Rights |
http://creativecommons.org/licenses/by-nc-nd/2.5/ |
Collection |
Poja Histology Collection - Respiratory System Subset |
ARK |
ark:/87278/s6rz2f95 |
Setname |
ehsl_heal |
ID |
890776 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6rz2f95 |