| Identifier |
20230314_nanos_sciplatform2_03 |
| Title |
In Vivo Application of Electric Fields Collaborate With rRHEB to Direct Optic Nerve Regeneration |
| Creator |
Timothy Kim; Sasha Medvidovic; Phillip Lam; Petcy Yao; Ege Iseri; Micalla Peng; Biju Thomas; Mahnaz Shahidi; Gianluca Lazzi; Kimberly Gokoffski |
| Affiliation |
(TK) (MP) Keck School of Medicine of USC; (SM) (PL) (PY) (EI) (BT) (MS) (JL) University of Southern California; (KG) Keck |
| Subject |
Optic Nerve Trauma and Treatment; Miscellaneous |
| Description |
Regenerating the optic nerve requires signals that both 'fuel' and 'steer' retinal ganglion cell (RGC) axon growth to appropriate targets. Although strategies to increase mammalian target of rapamycin (mTOR) activity have been employed to 'fuel' RGC axon regeneration, they are not as effective at 'steering' regeneration. Based on compelling evidence that electric field (EF) application does both, we investigated whether EFs-in conjunction with mTOR activation-direct more target-specific RGC axon regeneration than either treatment alone. |
| Date |
2023-03 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
2023 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS Annual Meeting 2023: Scientific Platform Session II |
| Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2023. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6rbfraa |
| Setname |
ehsl_novel_nam |
| ID |
2309959 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6rbfraa |
