Identifier |
20180306_nanos_posters_188 |
Title |
Genetics of Idiopathic Intracranial Hypertension |
Creator |
DonRaphael Wynn; Judith Warner; Kathleen Digre; Bradley Katz; Alison Crum; Margaret DeAngelis |
Affiliation |
(DW) (JW) (KD) (BK) (AC) (MD) John A Moran Eye Center, University of Utah, Salt Lake City, Utah |
Subject |
Pseudotumor Cerebri; High Intracranial Pressure; Headache |
Description |
Evidence suggests a genetic predisposition for idiopathic intracranial hypertension. Corbett et. al. described 27 patients with either definitive or probable IIH from eleven ascertained families. This demonstrates that IIH clusters in families. Additionally the IIH treatment trial (IIHTT) reported that 5% of the 165 patients studied had a family member with IIH. To date, no one has performed a rigorous genetic analysis of family members with IIH to better identify IIH-related genes and the potential contribution of genetics to the pathogenesis of this disease. We are conducting whole exome sequencing (WES) on DNA from the members of a large family with IIH in order to elucidate a potential genetic cause. |
Date |
2018-03 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2018 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS 2018: Poster Presentations |
Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
Publisher |
North American Neuro-Ophthalmology Society |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
Copyright 2018. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6q280fk |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
1309643 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6q280fk |