Identifier |
20180306_nanos_posters_262 |
Title |
Kayser-Fleischer Ring Detection and Quantification in Wilson's disease using Optical Coherence Tomography |
Creator |
Ruchika Batra; Pearse Keane; David Nicholl; Gideon Hirschfield; Alastair Denniston; Susan Mollan |
Affiliation |
(RB) Birmingham Neuro-ophthalmology Unit, Birmingham, Great Britain; (PK) NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital, London, Great Britain; (DN) Department of Neurology, City Hospital, Birmingham, Great Britain; (GH) Centre for Liver Research, NIHR Biomedical Research Unit, University of Birmingham, Birmingham, Great Britain; (AD) (SM) University Hospitals BirminghamNHS Trust, Queen Elizabeth Hospital, Birmingham, Great Britain |
Subject |
Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc); Eyelid & Adnexal Disease |
Description |
Delays in the diagnosis of Wilson's Disease (WD) arising from the challenging heterogeneity of presentation, lead to avoidable morbidity and mortality. Clinically a Kayser-Fleischer (KF) ring is useful in diagnosis, reported as being present in nearly all neurological WD, half of hepatic WD and less than half of presymptomatic WD. Most KF rings regress with medical therapy or liver transplantion, however, may return when treatment ceases. Lifelong monitoring of serum and urine is cumbersome for the patient and a reliable non-invasive disease activity score is sought. The aim of the study was to establish the feasibility of quantitative analysis of KF rings in established WD using non-invasive anterior segment optical coherence tomography (AS-OCT). |
Date |
2018-03 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2018 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS 2018: Poster Presentations |
Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
Publisher |
North American Neuro-Ophthalmology Society |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
Copyright 2018. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6n91b2x |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
1310593 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6n91b2x |