Identifier |
20080311_nanos_posters_034.pdf |
Title |
Acute Promyelocytic Leukemia (APML) Presenting with Papilledema and Venous Sinus Thrombosis |
Creator |
Melissa Ko; Michele Roullet; Larissa Bilaniuk; Susan Rheingold; Grant Liu |
Affiliation |
(MK) (MR) (LB) (GL) Hospital of the University of Pennsylvania, Philadelphia, PA; (SR) (GL) Children's Hospital of Philadelphia, Philadelphia, PA |
Subject |
Papilledema; Venous Sinus Thrombosis; Acute Promyeloeytic Leukemia |
Description |
APML, an AML subtype, has been recognized for a tendency of catastrophic hemorrhage. Thrombosis, an uncommon complication of APML, can manifest in the venous sinuses (VST). Generally, thrombosis is reported following all-trans retinoic acid (ATRA) treatment, which is prothrombotic likely from altered eytolcine production. ATRA has dramatically transformed APML's prognosis from one of the most fatal to the most curable AML subtype, by accelerating differentiation of promyeloeytes to mature neutrophils and resolving the coagulopathy. This is a case ofAPML presenting with papilledema secondary to VST. The etiology of the VST was from APML's natural coagulopathic course and not from ATRA treatment. |
Date |
2008-03-11 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2008 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS 2008: Poster Presentations |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
Rights Management |
Copyright 2010. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6n04cz1 |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
180860 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6n04cz1 |