The Relationship between Central Corneal Thickness (CCT) and Papilledema from Idiopathic Intracranial Hypertension (IIH)

Glaucoma studies have suggested that translaminar pressure gradients (TPG) may affect severity of optic nerve damage in glaucoma.(1) It has been demonstrated that CCT could possibly be a risk factor for developing ophthalmic disease from an altered TPG.(2) Alterations of TPG by decreasing intraocular pressure (IOP) have also been implicated in the development of papilledema.(3- 4) Subgroups of patients with IIH and papilledema are at higher risk for severe vision loss, including black patients, men, and patients; with fulminant presentations.(5) Our goal was to determine if CCT is related to severity of papilledema and vision loss in IIH.