Title |
Scheme of development of germinal centre in lymphatic nodule (human) |
Creator |
Poels, Lambert G. |
Contributor |
Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen |
Date |
2010-06-11 |
Subject |
follicle; antigen stimulation; scheme; germinal center |
Description |
A. primary nodule (or follicle) with mainly nave B lymphocytes and some memory cells, but no germinal centre; B. proliferation of lymphoblasts by mitosis (3,-->) and development of capillaries (*) in the centre of the follicle; C. so-called secondary nodule with lighter stained germinal centre with reticular cells, macrophages; D. larger maturing B lymphocytes (or follicle centre cells); rows of small nave B lymphocytes are circularly arranged A. rest situation of germinal centre with reduction of lymphocytes; few reticular cells, macrophages and plasma cells are present 1. mantle zone ; 2. lymphoblast; 3. mitotic figure; 4. capillary; 5. circularly arranged naive B lymphocytes and few T lymphocytes in the mantle zone; 6. reticular cell; 7. macrophage with so-called 'tingible bodies' (phagocytosis); 8. plasma cell |
Subtype |
Image |
Format |
image/jpeg |
Rights |
https://rightsstatements.org/page/CNE/1.0/ |
Collection |
Poja Histology Collection - Lymphatic Tissues and Organs Subset |
ARK |
ark:/87278/s6jm5czp |
Setname |
ehsl_heal |
ID |
890917 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6jm5czp |