Lymph node (human)

Stain: Azan. Part of the cortex of a lymph node with the capsule (1) and subcapsular (or marginal) sinus (2) filled with lymphocytes. Below the subcapsular sinus a darkly stained rim or corona (3) of small lymphocytes (B cells) surrounds the lucid stained germinal centre (4). The white spaces represent (intermediate) sinuses (5). Small arteries, including high endothelial venules (HEV) are indicated by (-->) in the interfollicular or paracortical area (T cell area).