Identifier |
wh_ch45_p2444 |
Title |
Walsh & Hoyt: Causes |
Creator |
Valerie A. Purvin, MD |
Affiliation |
Indiana University |
Subject |
Vascular Diseases; Venous Occlusive Disease; Venous Occlusions; Cerebral Venous Thrombosis; Causes |
Description |
A wide variety of conditions can cause CVT. These can be divided into congenital and acquired thrombophilias, abnormalities of blood flow, and disorders involving the vessel wall. In the pre-antibiotic era, septic CVT was relatively common, but in recent years prothrombotic states are more frequently identified. A number of congenital thrombophilias have been associated with an increased risk of CVT. The most commonly identified have been the factor V Leiden mutation and the G20210A-prothrombin gene mutation. Other studies have found associations with antiphospholipid antibodies, hyperhomocysteinemia, antithrombin III deficiency, protein S or C deficiency, and sickle cell disease. Occasional patients harbor more than one such mutation and in some patients a combination of congenital and acquired factors may cause thrombosis. The clinical corollary of this observation is that a full coagulation work-up should be undertaken in all patients with CVT even when an apparent inciting event, such as pregnancy, oral contraceptives, or recent surgery, has been identified. |
Date |
2005 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Relation is Part of |
Walsh and Hoyt's Clinical Neuro-Ophthalmology Walsh and Hoyt's Clinical Neuro-Ophthalmology |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Wolters Kluwer Health, Philadelphia |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-5890 |
Rights Management |
Copyright 2005. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6cv7s5z |
Setname |
ehsl_novel_whts |
ID |
185702 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6cv7s5z |