Oculomotor Abnormalities in Albinism

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Identifier 19860224_nanos_smoothpursuitsympos_04
Title Oculomotor Abnormalities in Albinism
Creator Jonathan D. Wirtschafter, MD, Professor, Departments of Ophthalmology, Neurology, and Neurosurgery, University of Minnesota, Minneapolis, MN
Subject Oculomotor Abnormalities; Albinism; Anatomic Abnormalities; Sensory System; Foveal Hypoplasia; Retinal Decussation Line
Description Although there are anatomic abnormalities in the sensory system (foveal hypoplasia and misrouting of retinofugal projections, the abnormal ocular movements observed (spontaneous unidirectional and bidirectional jerk or pendular nystagmus and absent true horizontal OKN) are not simply explained (Table 1). Foveal hypoplasia leading to degraded sensorimotor feedback does not explain the vertical stability nor the presence of nystagmus at or soon after birth particularly since the anatomic development of the fovea is not normally completed until 4 months after birth. Moreover foveal hypoplasia is an obligate feature of albinism while nystagmus is not. The alternative hypothesis is that optic pathway abnormalities result in directional errors of senorimotor feedback. The problem with this explanation is the need to explain the other forms of congenital nystagmus not associated with abnormal retinal projections.
Relation is Part of Smooth Pursuit Symposium
Contributor Primary Sharpe, James A
Contributor Secondary Wirtschafter, Jonathan D
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Type Text
Format application/pdf
Format Creation application/pdf
Source 1986 North American Neuro-Ophthalmology Society Annual Meeting
Rights Management Copyright 1986. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Language eng
ARK ark:/87278/s6ck1m5v
Setname ehsl_novel_nam
Date Created 2014-02-26
Date Modified 2021-05-06
ID 183571
Reference URL https://collections.lib.utah.edu/ark:/87278/s6ck1m5v