Trouble Reading

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Identifier walsh_2011_s3_c4
Title Trouble Reading
Creator Rebecca Stacy; Simmons Lessell
Affiliation (RS) (SL) Massachusetts Eye and Ear Infirmary, Boston, MA
Subject Immunologic Deficiency Syndromes; Common Variable Immunodeficiency; Leukoencephalopathy, Progressive Multifocal; Hemianopsia; Demyelinating Diseases
History A 60-year old female with a 4-week history of progressive difficulty reading and word comprehension. Previous history significant for a 20-year history of recurrent granulomatous iritis in OU and chronic variable immune deficiency (CVID), diagnosed 23 years previous with associated hepatitis and dermatitis.
Pathology Lesions in the left posterior temporal and occipital regions composed of foamy macrophages with severe demyelination and gliosis.
Disease/Diagnosis Progressive multifocal leukoencephalopathy in the setting of chronic variable immune deficiency (CVID)
Clinical VA: 20/30 OU; Right homonymous hemianopsia
Presenting Symptom Reading and comprehending difficulties
Neuroimaging MRI
Treatment Anticonvulsants; Antimalarials
Date 2011-02
References 1. Koralnik, I. New insights into progressive multifocal leukoencephalopahty. Curr Opin Neurol. 17: 366-370, 2004. 2. Narula S. et al., Progressive multifocal leukoencephalopathy in a patient with common variable immunodeficiency and abnormal CD8+ T-cell subset distribution, Ann Allergy Asthma Immunol, 98: 483-499, 2007.
Language eng
Format application/pdf
Type Text
Source 43rd Annual Frank Walsh Society Meeting
Relation is Part of NANOS Annual Meeting Frank B. Walsh Sessions; 2011
Collection Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2011. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s69p34j5
Setname ehsl_novel_fbw
ID 179047
Reference URL https://collections.lib.utah.edu/ark:/87278/s69p34j5