| Identifier | walsh_2011_s3_c4 |
| Title | Trouble Reading |
| Creator | Rebecca Stacy; Simmons Lessell |
| Affiliation | (RS) (SL) Massachusetts Eye and Ear Infirmary, Boston, MA |
| Subject | Immunologic Deficiency Syndromes; Common Variable Immunodeficiency; Leukoencephalopathy, Progressive Multifocal; Hemianopsia; Demyelinating Diseases |
| History | A 60-year old female with a 4-week history of progressive difficulty reading and word comprehension. Previous history significant for a 20-year history of recurrent granulomatous iritis in OU and chronic variable immune deficiency (CVID), diagnosed 23 years previous with associated hepatitis and dermatitis. |
| Pathology | Lesions in the left posterior temporal and occipital regions composed of foamy macrophages with severe demyelination and gliosis. |
| Disease/Diagnosis | Progressive multifocal leukoencephalopathy in the setting of chronic variable immune deficiency (CVID) |
| Clinical | VA: 20/30 OU; Right homonymous hemianopsia |
| Presenting Symptom | Reading and comprehending difficulties |
| Neuroimaging | MRI |
| Treatment | Anticonvulsants; Antimalarials |
| Date | 2011-02 |
| References | 1. Koralnik, I. New insights into progressive multifocal leukoencephalopahty. Curr Opin Neurol. 17: 366-370, 2004. 2. Narula S. et al., Progressive multifocal leukoencephalopathy in a patient with common variable immunodeficiency and abnormal CD8+ T-cell subset distribution, Ann Allergy Asthma Immunol, 98: 483-499, 2007. |
| Language | eng |
| Format | application/pdf |
| Type | Text |
| Source | 43rd Annual Frank Walsh Society Meeting |
| Relation is Part of | NANOS Annual Meeting 2011 |
| Collection | Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/ |
| Publisher | North American Neuro-Ophthalmology Society |
| Holding Institution | Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management | Copyright 2011. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK | ark:/87278/s69p34j5 |
| Setname | ehsl_novel_fbw |
| ID | 179047 |
| Reference URL | https://collections.lib.utah.edu/ark:/87278/s69p34j5 |