A Mystery Case of Proptosis, Optic Neuropathy, and Peripheral Neuropathy

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Identifier walsh_2012_s3_c3_ppt
Title A Mystery Case of Proptosis, Optic Neuropathy, and Peripheral Neuropathy
Creator Keung, Bonnie
Subject Charcot-Marie-Tooth Disease; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Multiple Sclerosis
Presenting Symptom A 23 year-old female with proptosis and ophthalmoplegia.
History Age 7 - headaches and vision loss to count fingers in left eye; Age 13 - diagnosed with multiple sclerosis; Age 22 - diplopia thought to be bilateral INO; identical twin with sequential bilateral optic neuritis at 8 years, diagnosis of multiple sclerosis at 12 years, and repeated exacerbations of gait impairment
Clinical 20/20 OU; left RAPD; 3 mm right proptosis; -3 adduction in right eye; -2 abduction in left eye; -1 elevation deficit bilaterally; one Lisch nodule; one cafe au lait spot less than 2 cm; Optic nerves appeared pale OS > OD.
Neuroimaging MRI
Pathology Nerve fascicles with loss of large and small myelinated nerve fibers; thin myelin sheathes and frequent 'onion-bulb' formations with concentric layers of Schwann cell processes
Disease/Diagnosis Combined central and peripheral myelinopathy
Relation is Part of Case presented at the NANOS 2012 Walsh Session, February 12
Contributor Primary Keung, Bonnie
Contributor Secondary Warner, Judith; Digre, Kathleen; Katz, Bradley; Chin, Steven; Shah, Lubdha; Eckart, Danielle
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2012-02-12
Type Text
Format application/pdf
Source 44th Annual Frank Walsh Society Meeting
Rights Management Copyright 2012. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Language eng
ARK ark:/87278/s65q5006
Setname ehsl_novel_fbw
Date Created 2012-06-07
Date Modified 2021-05-06
ID 179079
Reference URL https://collections.lib.utah.edu/ark:/87278/s65q5006