Identifier |
20150222_nanos_posters_224 |
Title |
Contrast Sensitivity Visual Acuity is Degraded in REM Sleep Behavior Disorder |
Creator |
Matthew J. Khayata; Whitney B. Hough' Peggy H. Vogt; Eric M. Keasler; Jacqueline M. Sanchez; Garrett Barr; David Y. Huang; Charles G. Maitland |
Affiliation |
(MJK) (WBH) (PHV) (EMK) (JMS) (GB) (CGM) Florida State University College of Medicine, Tallahassee, FL; (CGM) TMH Foundation Healthcare, Tallahassee, FL; (DYH) Tallahassee Pulmonary Clinic, Tallahassee, FL |
Subject |
REM Sleep Behavior Disorder; Contrast Sensitivity Visual Acuity; Alpha-Synuclein |
Description |
REM Sleep Behavior Disorder (RBD) is a sleep disorder that produces motor enactment during REM sleep. Although pathophysiology is uncertain, studies demonstrate nigrostriatal dopamine deficiencies in RBD patients,1 a condition frequently linked to alpha-synuclein-associated disorders i.e. Parkinson's disease (PD), characterized by cellular alpha-synuclein aggregation and death in dopamine producing cells. We previously reported contrast sensitivity visual acuity (CSVA) deficits in early-stage Parkinsonism.2 A recent study identified that misfolded alpha-synuclein, a regulator of dopamine synthesis, is present in the inner retina of PD patients.3 We therefore speculated that CSVA might be impaired in individuals with RBD. |
Date |
2015-02-22 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2015 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS 2015: Poster Presentations |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
Rights Management |
Copyright 2013. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s63z1dh5 |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
184587 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s63z1dh5 |