Chronic Optic Neuropathy Causes Decreases in Both Inner Retinal Blood Flow and Prelaminar Optic Nerve

It has been reported that patients with acute optic neuritis (ON) have good visual recovery, with return of highcontrast visual acuity (VA) to 20/40 or better in 95% of affected eyes. Vision-specific quality of life (QOL), however, is reduced among overall cohorts of patients with history of ON, even years following the acute event. We examined vision-specific QOL scores in a cohort of multiple sclerosis (MS) patients among the specific sub-group of subjects with history of ON and high-contrast VA of 20/40 or better in both eyes.