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TitleDescriptionSubjectCollection
201 Differences and Similarities Between Idiopathic Intracranial Hypertension, Ocular Myasthenia Gravis, Optic Neuritis, and Horner's In Children Vs. AdultsPediatric neuro-ophthalmology is more than just neuroophthalmology of little people. Compared with neuro-ophthalmology in adults, in the pediatric subspecialty the diseases are different, with greater emphases on congenital malformations and genetic disorders and less on vascular problems.Idiopathic Intracranial Hypertension (Pseudotumor Cerebri); Pediatric Optic Neuritis; Ocular Myasthenia Gravis; Horner's SyndromeNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
202 Walsh & Hoyt: Pediatric Myasthenia GravisAutoimmune MG can occur at any age. One clinical challenge in ""juvenile-onset"" myasthenia is to distinguish antibody-mediated disease from gene mutations affecting NMJ ion channels. Juvenile-onset autoimmune MG differs little from adult-onset disease, except that it may improve with age. It respon...Ocular Motor System; Pediatric Myasthenia GravisNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
203 Mitochondrial Ophthalmoplegia with Fatigable Weakness and Elevated Acetylcholine Receptor AntibodyAdult; Antibodies, blood; Biological Markers, blood; Biopsy; Diagnosis, Differential; Disease Progression; Electromyography; Electroretinography; Eye Movements, physiology; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Microscopy, Electron; Muscle Fatigue, physiology; Oculomotor Muscl...
204 The Effect of Corticosteroids on the Progression of Ocular Myasthenia to Generalized MyastheniaIn previously published reports, 49% to 69% of patients with Ocular Myasthenia (OMG) will progress to Generalized Myasthenia Gravis (GMG without any medical intervention. Of the patients with only ocular manifestations at onset who later develop symptoms of generalized myasthenia, 60% to 80% will do...Corticosteroids; Ocular Myasthenia; Myasthenia; Generalized Myasthenia GravisNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
205 Walsh & Hoyt: Eaton-Lambert Syndrome: A Paraneoplastic Disorder of the Neuromuscular JunctionA disorder resembling myasthenia gravis, occurring in patients with bronchogenic carcinoma, was first described by Anderson et al. in 1953. During the next decade, Eaton, Lambert, Rooke, and their associates at the Mayo Clinic studied the clinical and physiologic characteristics of this disorder in ...Neoplasms; Paraneoplastic Syndrome; Eaton-Lambert Syndrome; Paraneoplastic Disorder, Neuromuscular JunctionNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
206 Myasthenia gravis and Charcot-Marie-Tooth disease.Adult; Older people; Charcot-Marie-Tooth Disease; Edrophonium; Eye Diseases; Humans; Male; Muscular Atrophy; Myasthenia Gravis
207 Lid Nystagmus as a Sign of Intrinsic Midbrain DiseaseAstrocytoma/diagnosis; Astrocytoma/radiotherapy; Blepharoptosis/complications; Brain Neoplasms/diagnosis; Brain Neoplasms/radiotherapy; Child; Eye Movements; Eyelid Diseases/diagnosis; Humans; Magnetic Resonance Imaging; Male; Mesencephalon/pathology; Myasthenia Gravis/diagnosis; Nystagmus, Patholog...
208 Literature abstracts.
209 Literature abstracts.
210 Neuro-ophthalmic Manifestations of Checkpoint InhibitorsCheckpoint inhibitors, such as ipilimumab, nivolimumab, and pembrolizumab, have been reported to cause ophthalmic adverse events. While myasthenia gravis induced by these medications has been previously documented, other neuro-ophthalmic manifestations have been rarely reported. This study aims to i...Chemotherapy and Radiation Injury, Neuro-ophth & Systemic Disease (eg. MS, MG, Thyroid)Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
211 Myasthenia gravis-like syndrome induced by topical ophthalmic preparations. A case report.Cararact Extraction; Female; Humans; Middle Older people; Myasthenia Gravis; Ophthalmic Solutions; Propoxycaine; Syndrome; Tropicamide
212 Myasthenia ThymomaThe patient is a 46 year old woman who presented in July 1977 with horizontal double vision lasting two weeks. Three weeks later the left upper eyelid started to droop and by the end of the day the eye was closed. She had no ptosis of the right eye and no generalized fatigue. She consulted an intern...Unilateral Ptosis; Unilateral Lid Retraction; Myasthenic Lid Twitch; External Ophthalmoplegia; Ocular Myasthenia Gravis; Tensilon Test; Thymolipoma; Generalized Myasthenia Gravis; Unilateral Myasthenia Gravis; Myasthenic Ptosis; Lid Retraction; Lid TwitchNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
213 Concomitant Seropositive Ocular Myasthenia and Biopsy-Proven Temporal ArteritisOcular myasthenia gravis (OMG) and temporal arteritis (or giant cell arteritis, GCA) are autoimmune diseases that affect visual function. Although they can both occur alongside other autoimmune conditions, there are very few cases of co- existing OMG and GCA. We present a case of seropositive OMG wi...Neuro-ophth & Systemic Disease (eg. MS, MG, Thyroid); MyastheniaNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
214 Effect of Initial Prednisone Dosing on Ocular Myasthenia Control at 1 MonthOcular myasthenia gravis (OMG) is an autoimmune condition responsive to corticosteroids. Experts recommend corticosteroids as first line immunosuppressive treatment (1); however, no guidelines exist for initial dosing. Prior retrospective reports have suggested initial doses of 40-80 mg daily (2) bu...Neuro-ophth & Systemic Disease (eg. MS, MG, Thyroid), MyastheniaNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
215 Treatment of Ocular Myasthenia Gravis (Slides)Myasthenia gravis is caused by pathogenic autoantibodies to the postsynaptic neuromuscular junction. Clinically, this may affect any of the skeletal muscles causing variable weakness, which worsens with continued muscle activity. Ocular myasthenia gravis (OMG) may affect the levator palpebrae superi...Ocular Myasthenia; Treatment; Therapy; Pyridostigmine; Corticosteroids; Thymectomy; Azathioprine; Mycophenolate MofetilNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
216 Ipilimumab-Related Orbital Inflammation and Hypophysitis in Patients with Metastatic Melanoma: A Brief Case SeriesIpilimumab is a monoclonal antibody directed against cytotoxic T-lymphocyte antigen-4 used for the treatment of metastatic melanoma. The most frequent adverse reactions associated with Ipilimumab have been autoimmune disorders, including enteritis, uveitis and arthritis. Myasthenia Gravis and hypoph...Ipilimumab; Cytotoxic T-lymphocyte Antigen-4; Metastatic Melanoma; Myasthenia Gravis; Hypophysitis; Bilateral Orbital Edema; Diplopia; Orbital InflammationNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
217 Ocular MyastheniaExample of patient with myasthenia gravis. Demonstration of tensilon test. Patient shown to have bilateral ptosis, bilateral duction deficits, and left hypertropia. Discussion of techniques to observe subtle changes, such as bringing in a neutral observer or taking still photographs. Shows split-scr...Ocular Myasthenia; Myasthenia Gravis; Ptosis, Myasthenic; Tensilon TestNeuro-Ophthalmology Virtual Education Library - The Moran Eye Center Neuro-Ophthalmology Collection: https://novel.utah.edu/Moran/
218 Atrophy of Bilateral Extraocular MusclesAdult; Older people; Atrophy/diagnosis; Female; Humans; Magnetic Resonance Imaging; Male; Middle Older people; Mitochondrial Myopathies/complications; Myasthenia Gravis/complications; Oculomotor Muscles/pathology; Oculomotor Muscles/radiography; Tomography, X-Ray Computed
219 Autoimmune Acquired Rippling Muscle Disease and Myasthenia GravisHumans; Male; Middle Older people; Muscular Diseases; Myasthenia Gravis
220 Repetitive Ocular Vestibular Evoked Myogenic Potentials (oVEMP) Stimulation for Myasthenia Gravis: Comparison Of Stimulation ParadigmsEarly and accurate diagnosis is of utmost importance for the course and outcome of myasthenia gravis (MG). Recently, repetitive; ocular vestibular evoked myogenic potential (oVEMP) stimulation has been developed as a novel diagnostic tool for MG.; Quantification of extraocular muscle response decrem...Myasthenia, Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc) Eyelid & adnexal disease, Neuro-ophth & systyemic disease ( eg. MS, MG, thyroid), Ocular MotilityNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
221 Repetitive Ocular Vestibular Evoked Myogenic Potentials (oVEMP) Stimulation for Myasthenia Gravis: Comparison Of Stimulation ParadigmsEarly and accurate diagnosis is of utmost importance for the course and outcome of myasthenia gravis (MG). Recently, repetitive; ocular vestibular evoked myogenic potential (oVEMP) stimulation has been developed as a novel diagnostic tool for MG.; Quantification of extraocular muscle response decrem...Myasthenia, Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc) Eyelid & adnexal disease, Neuro-ophth & systyemic disease ( eg. MS, MG, thyroid), Ocular MotilityNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
222 Before TensilonExample of patient with myasthenia gravis. Demonstration of baseline examination, followed by administration of 2mg of tensilon, which is a test dose. Procedure for administration of tensilon test is described, including variations. Patient is then shown after being given 4mg of tensilon, with very ...Myasthenia Gravis; Tensilon TestNeuro-Ophthalmology Virtual Education Library - The Moran Eye Center Neuro-Ophthalmology Collection: https://novel.utah.edu/Moran/
223 Curtain Sign (Enhanced Ptosis) - Associated Image 1This is a 78-year-old male patient who presented with diplopia, right eyelid ptosis, and ophthalmoplegia. He had severe ptosis OD and pseudo-proptosis (lid retraction) OS at baseline, but when the right eyelid was manually elevated, there was marked enhanced ptosis of the left eyelid (Video). He was...Myasthenia GravIs; Clinical SignsNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
224 Curtain Sign (Enhanced Ptosis) - Associated Image 2This is a 78-year-old male patient who presented with diplopia, right eyelid ptosis, and ophthalmoplegia. He had severe ptosis OD and pseudo-proptosis (lid retraction) OS at baseline, but when the right eyelid was manually elevated, there was marked enhanced ptosis of the left eyelid (Video). He was...Myasthenia GravIs; Clinical SignsNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
225 Myasthenia Gravis Associated With Orbital Marginal Zone Lymphoma
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