Eccles Health Sciences Library
 
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TitleCurriculumDescriptionSubjectCollection
201 Acute Retrobulbar Optical Neuropathycurriculum_fellow; KBDdiseasesoftheopticnervePPT covering acute retrobulbar optic neuropathy, including ischemic, inflammatory, anterior ischemic optic neuropathy (AION) and non-arteritic anterior ischemic optic neuropathy (NAION); includes brainscan images for optic neuritis and multiple sclerosis; optic disk with LHON and PION. Anatomy: Opt...Optic Neuropathy, Ischemic; Giant Cell Arteritis; Edema; Multiple Sclerosis; Optic Atrophy, Hereditary, Leber; Ischemia; Hypotension; Edema; Optic Neuritis; Optic Nerve; Interferon-Beta-1a; Diseases of the Optic NerveNeuro-Ophthalmology Virtual Education Library - Alfredo A. Sadun Neuro-Ophthalmology Collection: https://novel.utah.edu/Sadun/
202 B114 Disc Swelling, Ischemic Papillopathies, AIONAION in a disc with an optic cup. Extraordinary exception with AION. Note ischemic vascular changes in disc surface. Anatomy: Optic disc. Pathology: Axoplasmic stasis due to ischemia. Disease/ Diagnosis: AION. Clinical: Visual loss.Disc Swelling; Ischemic Papillopathies; Anterior Ischemic Optic Neuropathy (AION)Neuro-Ophthalmology Virtual Education Library: William F. Hoyt Neuro-Ophthalmology Collection: https://novel.utah.edu/Hoyt/
203 B116 Disc Swelling, Ischemic Papillopathies, AIONTypical AION in disc with optic cup. December 23, 2996. 5 years later in same patient as B1_15a. Anatomy: Optic disc. Pathology: Axoplasmic stasis due to ischemia. Disease/ Diagnosis: AION. Clinical: Visual loss.Disc Swelling; Ischemic Papillopathies; Anterior Ischemic Optic Neuropathy (AION)Neuro-Ophthalmology Virtual Education Library: William F. Hoyt Neuro-Ophthalmology Collection: https://novel.utah.edu/Hoyt/
204 High Sensitivity C-Reactive Protein Measurements in Patients with Non Arteritic Anterior Ischemic Optic Neuropathy, a Clue to the Presence of a Microinflammatory ResponseNon arteritic anterior ischemic optic neuropathy is the most common cause for acute optic neuropathy in the elderly. The incidence of atherothrombotic risk factors in these individuals, including diabetes mellitus and hypertension, raises the possibility of common pathological mechanisms that contri...c reactive protein, ischemic optic neuropathyNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
205 Measurement of Optic Nerve Blood Velocity as a Function of Age in Normal SubjectsOptic nerve blood flow is thought to be an important factor in the development of anterior ischemic optic neuropathy. We measured the widths of Doppier-broadened frequency spectra of laser light sacttered from selected sites on the optic nerve head in 22 normal subjects between the ages of 16 and ...Optic Nerve Blood Flow; Anterior Ischemic Optic Neuropathy; Blood Flow, Age; Age Related Cerebral BloodflowNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
206 Retinal Ganglion Cell Apoptosis in AIONWe attempted to identify retinal ganglion cells undergoing apoptosis, a form of programmed cell death, in an eye of a patient with anterior ischemic optic neuropathy (AION). A 70-year-old right-handed white man woke up with painless loss of vision OS after thromboembolectomy of an aorto-femoral graf...Retinal Ganglion Cell; Aptosis; Anterior Ischemic Optic Neuropathy; Terminal Deoxynucleotide Transferase UTP-biotin End Nick LabelingNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
207 Variability of the RAPD Within a DayTo study the fluctuations of the relative afferent pupillary defect (RAPD) within a day. 10 normal subjects, 5 patients with previous anterior ischemic optic neuropathy (AION) and one patient with strabismic amblyopia underwent 5 sequential RAPD determinations at 8 am, noon and 4 pm (15 trials in on...Relative Afferent Pupillary Defect; Anterior Ischemic Optic Neuropathy; Strabismic AmblyopiaNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
208 Should Aspirin Be Prescribed to Prevent Recurrence in Nonarteritic Anterior Ischemic Optic Neuropathy
209 Peripapillary Choroidal Vascularity and Visual Correlates in Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)The peripapillary choroid shares a blood supply with and is directly apposed to the optic nerve, and therefore may contribute to the pathogenesis of non-arteritic anterior ischemic optic neuropathy (NAION). Prior studies evaluating peripapillary choroidal thickness (PCT) and choroidal vascularity in...Optic Neuropathy; Perimetry; Visual FieldsNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
210 24 Hour Blood Pressure Monitoring in Patients with Non-arteritic Anterior Ischemic Optic NeuropathyTemporary severe hypoperfusion of the optic nerve head with subsequent ischemia is believed to be the pathogenic mechanism in non-arteritic AION. Patients often report their visual loss upon awakening. It has thus been proposed that nocturnal hypotension may be a pathogenic factor both in normotensi...Blood Pressure Monitoring; Non-Arteritic Anterior Ischemic Optic Neuropathy; Hypoperfusion; Optic Nerve Head; IschemiaNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
211 50% of Non-Arteritic Anterior Ischemic Optic Neuropathy Occurs between 40-55 Years Old"Non-arteritic ischemic optic neuropathy (NAION) is the most common acute optic neuropathy in those older than 50.1-2 and young onset NAION has been reported in 4-23% of patients.1-4 Aging is a risk factor for NAION, and the normal rate of retinal ganglion cell axonal loss triples after 50.5 The aim...NAION, Age, Risk Factors, OCT, Visual FieldNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
212 AION Precipitants (Video)The September 2016 issue of the Journal of Neuro-Ophthalmology included a Point-Counter-Point section entitled "Does Nocturnal Hypotension Play a Causal Role in Nonarteritic Anterior Ischemic Optic Neuropathy?"1 The following includes an exerpt from that paper. A followup Letter to the Editor from D...NAION; Nocturnal Hypotension; 24 Hour Blood Pressure Monitoring; Time of Onset Visual Loss; Sleep Apnea; Snoring; Continuous Positive Airway Pressure; Ischemic; Non-Arteritic Anterior Ischemic Optic Neuropathy; Phosphodiesterase-5 (PDE5) Inhibitor; Sildenafil; Viagra; Cataract Surgery; Post-Cataract...Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
213 Dimensions of the Optic Nerve Head Neural Canal Using Enhanced Depth Imaging Optical Coherence Tomography in Non-Arteritic Ischemic Optic Neuropathy Compared to Normal SubjectsAn anatomically crowded scleral canal has been linked to the development of non-arteritic anterior ischemic optic neuropathy (NAION). Previous authors have described the superficial characteristics of a "disc at risk" in NAION. We sought to investigate the deeper structures of the optic nerve head n...Non-Arteritic Anterior Ischemic Optic Neuropathy; Enhanced Depth Imaging (EDI); Optical Coherence Tomography; Lamina Cribrosa; Disc at RiskNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
214 Laser-induced Optic Neuropathy as A Model to Study Neuro-protectionNonarteritic Anterior Ischemic Optic Neuropathy (NAION) is believed to result from insufficient blood flow to the optic nerve head. However, the precise mechanism of ischemia remains unclear. A successful experimental animal model would help us better understand the pathophysiology of the disease. T...Nonarteritic Anterior Ischemic Optic Neuropathy; Optic Nerve Head; Laser-Induced Optic Neuropathy; Neuro-Protection Animal Model; Mesoporphyrin IX; Photodynamic TherapyNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
215 Myocarditis and Arteritic Anterior Ischemic Optic Neuropathy Secondary to Giant Cell Arteritis (.pdf)Giant cell arteritis (GCA) is a primary vasculitis of medium and large vessels with a broad range of clinical presentations. Myocarditis is a rare known manifestation of GCA. We present a case of a 67 year old man who presented with acute systolic heart failure of unknown etiology. Development of ar...Giant Cell Arteritis, Arteritis Ischemic Optic Neuropathy, Myocarditis, HeadacheNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
216 Use of the Multifocal ERG to Differentiate Arteritic from Non-arteritic Anterior Ischemic Optic Neuropathy (AION)The differentiation of non-arteritic AION from arteritic AION due to giant cell arteritis is usually based on one or more of the following: optic nerve appearance, preceding amaurosis, bilateral involvement, systemic symptoms, serum laboratory tests, and ultimately a positive temporal artery biopsy....giant cell arteritis; anterior ischemic optic neuropathy; multifocal electroretinographyNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
217 Walsh & Hoyt: Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)IC-H3fiii-ischemic-optic-neuropathy-decompression-trialMost (94.7%) cases of AION are nonarteritic NAION is the most common acute optic neuropathy in patients over 50 years of age, with an estimated annual incidence in the United States of 2.310.2 per 100,000 population (2,100), accounting for at least 6,000 new cases annually. The prevalence of NAION i...Optic Nerve Diseases; Optic Neuropathy, Ischemic; Papilledema; Nonarteritic Anterior Ischemic Optic Neuropathy; NAION; AnteriorNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
218 Structure-Function Analysis of Nonarteritic Anterior Ischemic Optic Neuropathy and Age-Related Differences in OutcomeAdult; Older people; Aging; Cross-Sectional Studies; Female; Humans; Male; Middle Older people; Optic Disk; Optic Neuropathy, Ischemic; ROC Curve; Retinal Ganglion Cells; Retrospective Studies; Tomography, Optical Coherence; Visual Acuity; Visual Field Tests; Visual Fields
219 Should a Hypercoagulable Work-Up Be Performed on Young Patients With Nonarteritic Anterior Ischemic Optic Neuropathy
220 Literature CommentaryAdenocarcinoma; Older people; Biopsy; Cerebral Amyloid Angiopathy; Female; Hemianopsia; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Positron-Emission Tomography; Prosopagnosia; Tomography, X-Ray ComputedNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
221 Prothrombin G20210A Mutation Causing Nonarteritic Anterior Ischemic Optic Neuropathy in a Young Patient
222 Clomiphene Citrate Associated With Palinopsia
223 Nonarteritic Anterior Ischemic Optic Neuropathy NAION A Misnomer"The fact that vascular abnormalities such as disc hemorrhages and swelling are present at the time of visual loss in NAION, followed by peripapillary vascular narrowing and ensuing disc pallor is enticing, but not etiologically conclusive for ischemia. There is both optic disc as well as retinal ev...NAION, Optic Neuropathy, Diagnostic Tests, Vitreous Separation, Axonal Cytoskeleton FractureNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
224 Optical Coherence Tomography Angiography and Anterior Ischemic Optic Neuropathy (.pdf)OCT angiography (OCT-A) is a new technology allowing the imaging of retinal microvascular flow without the injection of an intravenous dye. It also allows the visualization of the peripapillary vascularization. Even if the most significant contribution to the vascularization of the optic nerve comes...Diagnostic Test, Optic NeuropathyNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
225 Nonarteritic Anterior Ischemic Optic Neuropathy: Exceptions to the Rules
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