Videos, clinical notes and related presentations concerning neuro-ophthalmological and neurovisual disorders collected during Dr. Wray's work as the Director of Neuro-Visual Disorders at Massachusetts General Hospital.
Shirley H. Wray, M.D., Ph.D., FRCP, Professor of Neurology Harvard Medical School, Director, Unit for Neurovisual Disorders, Massachusetts General Hospital.
NOVEL: https://novel.utah.edu/
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Filters: Collection: ehsl_novel_shw
| Identifier | Title | History | Subject | ||
|---|---|---|---|---|---|
| 201 |
 |
Multiple_Sclerosis_2008 | Multiple Sclerosis | ||
| 202 |
 |
Multiple_Sclerosis_Lateropulsion | Multiple Sclerosis Lateropulsion | This 44 year old woman has a diagnosis of Multiple Sclerosis. | |
| 203 |
 |
Myasthenia_Gravis_guest_lecture | Myasthenia Gravis (Guest Lecture) | The patient is a 46 year old woman who presented in July 1977 with horizontal double vision lasting two weeks. Three weeks later the left upper eyelid started to droop and by the end of the day the eye was closed. She had no ptosis of the right eye and no generalized fatigue. She consulted an in... | Unilateral Ptosis; Unilateral Lid Retraction; Myasthenic Lid Twitch; External Ophthalmoplegia; Ocular Myasthenia Gravis; Tensilon Test; Thymolipoma; Generalized Myasthenia Gravis; Unilateral Myasthenia Gravis; Ptosis - Myasthenic; Lid Retraction; Lid Twitch |
| 204 |
 |
Myasthenia_Thymoma | Myasthenia Thymoma | The patient is a 46 year old woman who presented in July 1977 with horizontal double vision lasting two weeks. Three weeks later the left upper eyelid started to droop and by the end of the day the eye was closed. She had no ptosis of the right eye and no generalized fatigue. She consulted an in... | Unilateral Ptosis; Unilateral Lid Retraction; Myasthenic Lid Twitch; External Ophthalmoplegia; Ocular Myasthenia Gravis; Tensilon Test; Thymolipoma; Generalized Myasthenia Gravis; Unilateral Myasthenia Gravis; Ptosis - Myasthenic; Lid Retraction; Lid Twitch |
| 205 |
 |
Neuroblastoma | Neuroblastoma | The patient is Case 27-1995 Case Records of the Massachusetts General Hospital (New Eng. J Medicine 1995, 333:579-586). The discusser was Dr. Elizabeth Engle, Associate Professor of Neurology, Harvard Medical School. The baby girl was born after a 30 week gestation, with a birth weight of 1.25 k... | Downbeat Nystagmus; Paraneoplastic Opsoclonus; Neuroblastoma; Primary Position Downbeat Nystagmus; Ataxia; Paraneoplastic Downbeat Nystagmus |
| 206 |
 |
Ocular_Motor_Apraxia_guest_lecture | Ocular Motor Apraxia (Guest Lecture) | Congenital Ocular Motor Apraxia; Head Thrust | |
| 207 |
 |
Ocular_Myasthenia_Gravis_guest_lecture | Ocular Myasthenia Gravis (Guest Lecture) | Ocular Myasthenia Gravis; Ptosis - Myasthenic; Familial Myasthenia Gravis; Unilateral Ptosis; Unilateral Myasthenia Gravis | |
| 208 |
 |
Oculomasticatory_Myorhythmia_guest_lecture | Oculomasticatory Myorhythmia (Guest Lecture) | Somnolence; Supranuclear Paralysis of Up and Downgaze; Pendular Vergence Oscillations; Oculomasticatory Myorhythmia; Tropheryma Whippelii - Infection; CNS Whipple's Disease; Supranuclear Paralysis of Up and Downgaze Infection - Whipple's Disease; Oculomasticatory Myorhythmia (Whipple's) | |
| 209 |
 |
One_and_Half_Syndrome | One and a Half Syndrome | One-and-a-Half Syndrome; Abducens Nucleus; Esotropia of the Ipsilateral eye; Paralytic Pontine Exotropia | |
| 210 |
 |
Overview_of_TDP_43_guest_lecture | Overview of TDP 43 (Guest Lecture) | ||
| 211 |
 |
Palatal_Tremor | Palatal Tremor | Palatal Tremor; Acquired Pendular Oscillations; Ocular Myoclonus; Inferior Olive; Oculopalatal Tremor Rhythmic Hyperactivity | |
| 212 |
 |
Paraneoplastic_Ocular_Flutter | Paraneoplastic Ocular Flutter | The patient is a 58 year old woman with known hypertension. In 1994, two weeks prior to admission she had a dramatic change in behavior with insomnia, agitation and depression. This was accompanied by "ringing of hands and anxiety for no apparent reason". She became anorexic, lost 15 pounds ... | Ocular Flutter; Oscillopsia; Trunkal Ataxia; Paraneoplastic Cerebellar Syndrome; Small Cell Carcinoma of the Lung; Paraneoplastic Ocular Flutter; Flutter |
| 213 |
 |
Paraneoplastic_Opsocolonus | Paraneoplastic Opsocolonus | This patient is the index case of the Anti-Ri antibody, published in Annals of Neurology in 1988 (4). The Anti-Ri antibody is recognized to be a paraneoplastic marker in patients with breast and gynecological malignancies (10). The history of this case is particularly important because she was in... | Opsoclonus; Ocular Flutter; Oscillopsia; Saccadic Oscillations; Paraneoplastic Cerebellar Syndrome; Adenocarcinoma of the Breast; Anti-Ri Antibody; Paraneoplastic Opsoclonus; Paraneoplastic Ocular Flutter; Saccadomania |
| 214 |
 |
Paraneoplastic_Upbeat_Nystagmus | Paraneoplastic Upbeat Nystagmus | This case was presented to the Clinical Eye Movement Society at the American Neurological Association Meeting in October 2009. The patient is a 65 year old woman who was in good health until seven weeks prior to admission. On June 22/09 on the return flight from her daughter's wedding in Oregon she ... | Upbeat Nystagmus; Lid Nystagmus; Square Wave Jerks (Saccadic Oscillations); Saccadic Dysmetria; Saccadic Pursuit; Paraneoplastic Syndrome; Paraneoplastic Upbeat Nystagmus; Pancreatic Endocrine Carcinoma; Anti-Hu - Associated Paraneoplastic Encephalitis |
| 215 |
 |
Parasellar_Meningioma | Parasellar Meningioma | This patient is a 58 year old woman from Peru who, in 1975, developed intermittent headaches and right retro-orbital eye pain. She was seen by several ophthalmologists in South America who were unable to make a diagnosis. In March 1977 she awoke one morning with vertical diplopia most marked on... | Ptosis; Third Nerve Palsy; Aberrant Reinnervation of the Third Nerve; Oculomotor Nerve; Parasellar Meningioma; Cavernous Sinus Syndrome; Unilateral Oculomotor Third Nerve Palsy; Unilateral Third Nerve Palsy |
| 216 |
 |
Parkinsons_Disease | Parkinson's Disease | Parkinson's Disease | |
| 217 |
 |
Parkinsons_Disease_guest_lecture | Parkinson's Disease (Guest Lecture) | Parkinson's Disease | |
| 218 |
 |
Pendular_Oscillations | Pendular Oscillations | This 37 year old woman has had progressive multiple sclerosis (MS) affecting the cerebellum and brainstem for 6 years. Neurological examination: Titubation Dysarthria Incoordination of the extremities Ataxic gait Spastic paraparesis with generalized hyperreflexia and extensor plantar responses. ... | Pendular Horizontal Oscillations; Left Beating Nystagmus; Obtrusive Saccades; Bilateral Gaze Evoked Nystagmus; Saccadic Dysmetria; Oscillopsia; Titubation; Ataxia; Multiple Sclerosis; Primary Position Horizontal Nystagmus; Gaze Evoked Horizontal Nystagmus; Horizontal Saccadic Dysmetria |
| 219 |
 |
Pendular_Vertical_Oscillations | Pendular Vertical Oscillations | Pendular Vertical Oscillations | |
| 220 |
 |
Pontine_Infarction | Pontine Infarction | The patient is a 62 year old right handed man, status post myocardial infarction in 1989 and on Coumadin. In 1993 he presented with a history of three separate TIAs 1. Instantaneous perioral tingling and/or numbness lasting less than 1 minute. 2. Episodic numbness of the right hand and foot lasti... | Unilateral Internuclear Ophthalmoplegia; Unilateral Horizontal Gaze Palsy; Upbeat Nystagmus on Upgaze; Convergence Normal; Fisher's One-and-a-Half Syndrome;Pontine Infarct; Unilateral Horizontal Gaze Palsy Infarct; Abducting Nystagmus |
| 221 |
 |
Progressive_External_Ophthalmoplegia | Progressive External Ophthalmoplegia | Progressive External Ophthalmoplegia | |
| 222 |
 |
Progressive_Supranuclear_Palsy | Progressive Supranuclear Palsy | Progressive Supranuclear Palsy | |
| 223 |
 |
Saccades_guest_lecture | Saccades (Guest Lecture) | "Normal Eye Movements; Examination, Ocular; Saccades; Optokinetic Nystagmus Drum (OKN Drum); Pursuit; Ocular Motility" | |
| 224 |
 |
Selective_Saccadic_Palsy | Selective saccadic palsy | This case is published courtesy of Scott D.Z. Eggers, M.D., Department of Neurology, Mayo Clinic College of Medicine (1). The patient is a healthy 50 year old woman who underwent otherwise uncomplicated aortic valve replacement for an incidentally discovered ascending aortic aneurysm. Upon awakeni... | Selective Saccadic Palsy after Cardiac Surgery; Supranuclear Gaze Palsy; Ocular Motility; Bilateral Horizontal Gaze Palsy Hypoxia; Pontine Hypoxia; Cerebral Hypoxia |
| 225 |
 |
Supranuclear_Paralysis_of_Downgaze | Supranuclear Paralysis of Downgaze | John Trojanowski and I published this case in Neurology in 1980.(12) At that time, it was one of the first of five reports in the literature of the pathological localization of lesions in the midbrain that are responsible for selective supranuclear paralysis of downgaze. This case is of particula... | Somnolence; Supranuclear Paralysis of Downgaze; Vertical Oculocephalic Reflex Normal; Absent Convergence; Skew Deviation; Ocular Tilt Reaction; Artery of Percheron; Midbrain Infarct; Supranuclear Paralysis of Downgaze Infarct |