The Alfredo A. Sadun Neuro-Ophthalmology Collection: A Professor of Ophthalmology and Neurological Surgery at the USC Keck School of Medicine, Dr. Sadun with a team of researchers at the Doheny Eye Institute pioneered research in optic nerve dysfunction in patients with Alzheimer's disease. Contains his "100 best lectures." Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor Ophthalmology & Neurological Surgery, Doheny Eye Institute, Keck School of Medicine at USC.
NOVEL: https://novel.utah.edu/
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| Title | Description | Type | ||
|---|---|---|---|---|
| 51 |
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Visual Variants in Nature | Comparison of visual systems of various species. Anatomy: Retina; Pupil; Cones (Retina); Rods (Retina); Lens, Crystalline. | Text |
| 52 |
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Leber's Hereditary Optic Neuropathy: New Lessons From a Giant Pedigree in Brazil | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis; includes several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Pres... | Text |
| 53 |
 |
Apoptosis in LHON: An ROS Explanation | A slide presentation describing apoptosis in LHON; includes several images of optic nerve and optic disk. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. | Text |
| 54 |
 |
The Diagnostic Workup in Patients With Optic Neuropathies (Metodo diagnostico) | Slideshow presentation with images of optic disc with edema and "Positive temporal artery biopsy". Presenting Symptom: Hyperopia; Metamorphopsia. Anatomy: Optic nerve; Macula Lutea; Optic disc. Disease/Diagnosis: Optic neuritis; Macular edema; Optic neuropathy, Ischemic. | Text |
| 55 |
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Leber's Hereditary Optic Neuropathy: A Very Large New Pedigree in Brazil | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis. Includes several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Optic disk. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Blindnes... | Text |
| 56 |
 |
Subclinical Visual Abnormalities in Carriers With 11778 LHON from a 300 Member Brazilian Pedigree | Report of a multi-year international field investigation to rural Brazil to study a cluster of LHON, including its genetic roots. Presenting Symptom: Scotoma; Telangiectasis; Blindness. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells; Reactive oxygen species. Pathology: Slides showing LHON ... | Text |
| 57 |
 |
Mitochondrial Optic Neuropathies (MON) | Combination of two presentations on optic nerve diseases, covering the cases in Cuba and Brazil. Titles: Cuban epidemic of optic neuopathy: even zealots must eat, or, Conversations with Castro and Leber's hereditary optic neuropathy: a very large new pedigree in Brazil; includes several images of ... | Text |
| 58 |
 |
Acute Retrobulbar Optical Neuropathy | PPT covering acute retrobulbar optic neuropathy, including ischemic, inflammatory, anterior ischemic optic neuropathy (AION) and non-arteritic anterior ischemic optic neuropathy (NAION); includes brainscan images for optic neuritis and multiple sclerosis; optic disk with LHON and PION. Anatomy: Opt... | Text |
| 59 |
 |
A Neuro-Ophthalmologist's View of RGC Apoptosis and Neuroprotection | Slide presentation with several microscopic images demonstrating cell death, LHON, AIDS. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Phosphopyruvate Hydratase; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber; Acquired Immunodeficiency Syndrome; Glaucoma. Presen... | Text |
| 60 |
 |
Atypical Optic Neuropathies | A discussion of atypical optic neuropathies. Anatomy: Optic nerve; Optic disc. Pathology: Slides showing LHON. Disease/Diagnosis: Optic neuropathy, Ischemic; Optic atrophy, Hereditary, Leber; Toxic optic neuropathy. Presenting Symptom: Optic neuritis; Eye hemorrhage; Retinal vasculitis; Dyschromatop... | Text |
| 61 |
 |
Extremely High Resolution Magnetic Resonance Imaging of the Human Optic Nerve Head | MRI imagery of optic nerves demonstrates ability to identify cases of Leber's Hereditary Optic Neuropathy (LHON); includes MRI images of optic nerves. Anatomy: Optic nerve. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. | Text |
| 62 |
 |
Leber's Hereditary Optic Neuropathy: New Insights? | Several microscopic images of optic nerve with LHON. Anatomy: Optic nerve. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Scotoma; Dyschromatopsia. | Text |
| 63 |
 |
Pentoxifylline Suppression of TNF-Alpha Mediated Axonal Degeneration in the Rabbit Optic Nerve | Presenting Symptom: Dyschromatopsia. Anatomy: Optic nerve. Disease/Diagnosis: Acquired Immunodeficiency Syndrome; Demyelinating autoimmune diseases, CNS. Treatment: Pentoxifylline. | Text |
| 64 |
 |
The Diagnostic Workup in Patients With Optic Neuropathies | Slideshow presentation with images of optic disc with edema and optic atrophy. Presenting Symptom: Telangiectasis; Dyschromatopsia; Scotoma. Anatomy: Optic nerve; Optic disc; Phosphopyruvate Hydratase; Enolase. Disease/Diagnosis: Optic neuritis; Macular edema; Optic neuropathy, Ischemic; Optic atrop... | Text |
| 65 |
 |
Pupils and Fields: The Importance of Assessing the Optic Nerve | Presenting Symptom: Anisocoria; Adie syndrome; Scotoma; Afferent pupillary defect; Horner Syndrome; Edema; Papilledema; Optic nerve; Pupil; Optic disc. Anatomy: Optic nerve; Pupil; Optic disc. Disease/Diagnosis: Afferent pupillary defect; Horner Syndrome; Edema; Papilledema. | Text |
| 66 |
 |
Cuban Epidemic of Optic Neuropathy: Even Zealots Must Eat, or, Conversations with Castro | A team of neuro-opthalmologists visits Cuba in 1993 and 1994, and attempts to treat patients with vision disorders. Anatomy: Optic nerve; Structure of cribriform plate. Disease/Diagnosis: Optic nerve diseases; Blindness; Ambliopia; Alcoholic neuropathy. Treatment: Folate. Presenting Symptom: Ataxia;... | Text |
| 67 |
 |
Cuban Epidemic of Optic Neuropathy: Even Zealots Must Eat, or, Conversations with Castro | A team of neuro-opthalmologists visits Cuba in 1993 and 1994, and attempts to treat patients with vision disorders. Anatomy: Optic nerve. Disease/Diagnosis: Optic nerve diseases; Alcoholic neuropathy. Treatment: Folate. Presenting Symptom: Blindness; Ambliopia; Ataxia; Paresthesia; Hyporeflexia. | Text |
| 68 |
 |
Jonathan D. Wirtschafter, MD, FACS, Frank E. Burch Professor of Ophthalmology | Overview of the life of Jonathan D. Wirtschafter on the occasion of the first annual Wirtschafter Lectureship, in August of 2003. Sadun gave the lecture, recapping an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis. Includes several images o... | Text |
| 69 |
 |
Optic Disc Edema: Evaluating the Swollen Disc | Presentation at AAO 2007 meeting, distinguishing Optic disc edema from papilledema. Includes several images of optic disc, normal and with edema and papilledema. Anatomy: Optic disc. Disease/Diagnosis: Retinal edema; Papilledema | Text |
| 70 |
 |
Apoptosis of Retinal Ganglion Cells | Presented at a conference on neuroprotection at Sedona, Arizona, 2002; includes several microscopic images demonstrating cell death. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Cytokines. Disease/Diagnosis: Glaucoma. | Text |
| 71 |
 |
Induction of Apoptosis by Mitochondrial Impairment in LHON and Related Diseases | Slide presentation includes six pairs of microscopic slides showing LHON and control examples of optic nerve. Anatomy: Optic nerve. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. | Text |
| 72 |
 |
Circadian Rhythms: How Much Retina Do We Need for a Good Night's Sleep? | Discusses importance of the health of the retinohypothalamic tract in the maintenance of circadian rhythm. Anatomy: Retina; Hypothalamus; Retinal ganglion cells; Pineal gland. Disease/Diagnosis: Retinal diseases; Sleep disorders, Circadian rhythm. | Text |
| 73 |
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Toxic Optic Neuropathies: How Much Evidence Should it Take to Convict? | A critique of claims that the drug Amiodarone causes optic neuropathies. Presenting Symptom: Scotoma; Dyschromatopsia. Anatomy: Optic nerve. Disease/Diagnosis: Toxic optic neuropathy. | Text |
| 74 |
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Beyond the Margulis Hypothesis: The Time Bomb Within Us | Presented at Harvard, 2005; includes several images of optic disc with LHON. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Dyschromatopsia; Scotoma. | Text |
| 75 |
 |
How Strong is the Case for an Association Between PDE5 Inhibitors and NAION? | Anatomy: Optic nerve. Disease/Diagnosis: Optic Neuropathy, Ischemic; Toxic optic neuropathy. Presenting Symptom: Ischemia; Scotoma; Dyschromatopsia. | Text |