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TitleDescriptionSubject
26 Botulinum ToxinSummary: • Mechanism of botulinum toxin o Botox cleaves SNARE proteins, which are necessary for the release of acetylcholine containing vesicles in the pre-synaptic membrane o As a result, no acetylcholine will bind to the post-synaptic acetylcholine receptors • Uses of botulinum o Cosmetic > Of...Botox; Hemifacial Spasm; Blepharospasm; Migraine; Strabismus
27 Brown SyndromeSummary: Brown Syndrome • Constellation of oculomotor findings o Will have defect in ad-duction of the elevated eye o Unilateral • Etiology o Congenital forms o Acquired forms > Inflammatory > Mass compression > Muscle paresis • Pathophysiology o Can be due to issue with superior oblique, troc...Brown Syndrome; Oculomotor
28 CABG Related Vision LossDr. Lee lectures medical students on the subject of CABG related vision loss.CABG; Ischemic Optic Neuropathy; Post-operative
29 CRAO/NAIONSummary: CRAO/NAION: 1. Risk factors for both 2. Presentation a. Patient has vasculopathic factors i. Hypertension ii. Diabetes iii. Hyperlipidemia iv. Smoker b. Acute unilateral vision loss c. Ipsilateral RAPD (relative afferent papillary defect) d. This presentation could result from CRAO or NAION...CRAO; NAION; Vascular; Embolic
30 Carotid Artery Disease in OphthalmologyDr. Lee lectures medical students on the subject of carotid artery disease in ophthalmology.Carotid Artery; Carotid Artery Disease; Vision Loss; Amaurosis Fugax; Vasculitis; Giant Cell Arteritis; Horner's Syndrome; Emboli; Homonymous Hemianopsia; Occlusive Disease; Hemorrhage
31 Carotid Cavernous FistulaSummary: Carotid Cavernous fistula • Abnormal connection between the internal or external carotid artery and the cavernous sinus, skipping a capillary bed • Arteriovenous fistula: Carotid is the artery and cavernous sinus is the vein • Cranial nerve V1 is often involved, it is free floating in...Fistula; Cavernous Sinus; Arteriovenous
32 Central Retinal Artery Occlusion: Stroke Work-UpSummary: • We discussed two different strokes in the eye o Optic Nerve Stroke: Non-arteritic anterior ischemic optic neuropathy (NAION) o Retina Stroke: Central retinal artery occlusion (CRAO) • Approach to CRAO o CRAO is a stroke! o Urgent Stroke Work-Up: Call Stroke Team, Send to Stroke ER, an...CRAO; Stroke
33 Cerebellar Flocculus and Downbeat NystagmusDr. Lee lectures medical students on the subject of cerebellar flocculus.Nystagmus; Cerebellar Flocculus; Downbeat Nystagmus; Saccades
34 Cerebral PolyopiaSummary: • Monocular diplopia: each eye alone o Monocular problem: horizontal or vertical misalignment, neuron o Split between unilateral vs bilateral > Differentiation: Does the diplopia go away with covering either eye? o Unilateral problems: double vision goes away with covering either eye beca...Monocular Diplopia; Binocular Diplopia; Misalignment
35 Cerebral Venous Sinus ThrombosisDr. Lee lectures medical students on cerebral venous sinus thrombosis.Neuro-Ophthalmology; Venous; Thrombosis; Medical Condition
36 Charles Bonnet SyndromeDr. Lee lectures medical students on Charles Bonnet syndromeHallucinations; Vision Loss
37 Charles Bonnet Syndrome in the Hemianopic FieldSummary: • Charles Bonnet syndrome o Visual formed hallucinations (often of little people) o Other key features > Vision loss > Insight into the unreal nature of the phenomena > No auditory component • If auditory component exists: o Patient awake, alert, and oriented? o Causes can include: > De...Charles Bonnet Syndrome; Hallucinations; Visual Loss; Neurodegenerative Disorders
38 Chiari MalformationsDr. Lee lectures medical students on chiari malformationsChiari; Skew
39 ChordomaSummary: • Notochord general overview: o Present in organisms in the phylum Chordata o Humans fall under this category o In humans, the notochord eventually becomes the nucleus pulposus • Potential problems arising from the notochord o Can get stuck at either the clivus or the sacrum o Clival le...Chordoma; Notochord; Chondrosarcoma
40 Chronic Progressive External Ophthalmoplegia (CPEO)Summary • Chronic Progressive External Ophthalmoplegia (CPEO) o Definition -Ophthalmoplegia - two eyes don't move properly -External • Only extraocular muscles (lids and muscles of eye) affected • Intraocular muscles are not affected; pupils are spared -Chronic and progressive o Common present...CPEO; Mitochondria; Ophthalmoplegia; Ptosis
41 Corneal Neuropathic PainDr. Lee lectures medical students on the subject of corneal neuropathic pain.Cornea; Neuropathy; Confocal; Small Fiber
42 Cortical Visual ImpairmentSummary: • Cortical Visual Impairment o Term preferred over cortical blindness as patient does not need to be blind o Impaired with vision due to problem in the occipital cortex o Any lesion behind the optic chiasm bodies > homonymous hemianopsia on the contralateral sides of the lesion. • Poste...Cortical Visual Impairment; Occipital Cortex; Cerebral Visual Impairment
43 Cotton Wool Patches in Neuro-opDr. Lee lectures medical students on cotton wool patches in neuro-ophthalmology.Cotton Wool Patches; Neuro-Ophthalmology; Medical Condition
44 CraniopharyngiomaSummary: • Craniopharyngioma o Cranio = head o Pharyngioma = pharynx • Two embryologic origins o Posterior pituitary -Neuroectoderm origin (diencephalon) -Projecting down ("stalactite") o Anterior pituitary -Surface ectoderm origin (pharynx) -Projecting up ("stalagmite") o Rathke's cleft -Betwee...Craniopharyngioma; Mass; Suprasellar; Sella; Bitemporal Field Loss
45 Cupping in AIONDr. Lee lectures medical students on the subject of cupping in AION.Optic Neuropathy; Giant Cell Arteritis; Ischemia
46 Diabetes in Neuro-OphthalmologyDr. Lee lectures medical students about the role of diabetes in neuro-ophthalmology.Pathology; Diabetes; Neuroanatomy
47 Diplopia: Points to ConsiderSummary: • Diplopia (seeing two images) can be grouped into being binocular or monocular o Binocular diplopia involves both eyes being open -One eye looks at target while the other does not -Covering one of either eye makes double vision disappear -Treatment requires neuro-ophthalmology • Can af...Diplopia; Pinhole; Misalignment
48 Dominant Optic AtrophyDr. Lee lectures medical students on dominant optic atrophy.DOA; OPA1; Pseudo-glaucomatous Cupping; Central Scotoma; Cecocentral Scotoma; ADOA Plus
49 Dorsal Midbrain Syndrome and Parinaud SyndromeDr. Lee lectures medical students on dorsal midbrain syndrome.Pathologies; Paresis; Neuroanatomy
50 Duane SyndromeSummary: • Duane Syndrome -congenital absence of 6th cranial nerve o Types 1. Problems with abduction 2. Problems with adduction 3. Problems with both abduction and adduction 4. Paradoxical adduction with attempted abduction o DDx > Sixth nerve palsy > INO > Esotropia/Exotropia o Features > Eyes a...Duane Syndrome; Cranial Nerves; Sixth Cranial Nerve
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