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Title | Description | Subject | Collection |
1 |
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The Effect of 4-aminopyridine on the Velocity Versional Dysconjugacy Index (VDI), an Objective Ocular Motor Metric of Dysconjugacy Associated with INO in MS Patients, During High Precision Escalation in Core Body Temperature | The primary goal of the study was to test the hypothesis that the potassium channel blocker, 4-aminopyridine (4-AP), could mitigate a precisely defined heat stress-induced worsening in the ocular motor dysconjugacy associated with internuclear ophthalmoparesis (INO), in patients with Multiple Sclero... | 4-aminopyridine; Potassium Channel Blocker; Ocular Motor Dysconjugacy; Internuclear Ophthalmoparesis; Multiple Sclerosis; Uhthoff's Phenomenon | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
2 |
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One and a Half Syndrome | Slideshow describing condition. | Abducens Nuclear Lesion; Abducting Nystagmus; Cavernous Angioma; Convergence Absent; Convergence Normal; Esotropia; Facial Palsy; Facial Weakness; Fisher's One-and-a-Half Syndrome; Gaze Evoked Upbeat Nystagmus; Multiple Sclerosis; Pendular Vertical Oscillations; Pontine Hemorrhage; Pontine Infarct;... | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
3 |
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Brain MRI in Multiple Sclerosis | Slideshow describing condition. | Abducting Nystagmus; Bilateral Internuclear Ophthalmoplegia; Botulinum Toxin Therapy; Gaze Evoked Downbeat Nystagmus; Horizontal Pendular Nystagmus; Horizontal Saccadic Dysmetria; Lid Nystagmus; Multiple Sclerosis; Normal Convergence; Oscillopsia; Pendular Horizontal Oscillations; Saccadic Dysmetri... | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
4 |
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Multiple Sclerosis 2008: Bench to Bedside….and Back Again, The Raymond Adams Lecture | Slideshow describing condition. | Abducting Nystagmus; Bilateral Internuclear Ophthalmoplegia; Botulinum Toxin Therapy; Gaze Evoked Downbeat Nystagmus; Horizontal Pendular Nystagmus; Horizontal Saccadic Dysmetria; Lid Nystagmus; Multiple Sclerosis; Normal Convergence; Oscillopsia; Pendular Horizontal Oscillations; Saccadic Dysmetri... | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
5 |
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Bilateral Internuclear Ophthalmoplegia | Slideshow describing condition. | Abducting Nystagmus; Bilateral Internuclear Ophthalmoplegia; Botulinum Toxin Therapy; Gaze Evoked Upbeat Nystagmus; Horizontal Pendular Nystagmus; Lid Nystagmus; Multiple Sclerosis; Pendular Horizontal Oscillations; Upbeat Nystagmus | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
6 |
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Neuro-Ophthalmology and Systemic Disease -- An Annual Review (1993) | | Acquired Immunodeficiency Syndrome/complications; Animals; Cat-Scratch Disease/complications; Eye Diseases/etiology; Eye Diseases/genetics; Humans; Multiple Sclerosis/complications; Nervous System Diseases/complications; Nervous System Diseases/genetics; Paraneoplastic Syndromes/complications; Vascu... | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
7 |
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Damping of Monocular Pendular Nystagmus with Vibration | Acquired pendular nystagmus (APN) may be monocular or binocular, vary in trajectory, and consists of pseudo-sinusoidal oscillations, that are transiently-abolished by saccades and blinks. APN results in highly-disabling oscillopsia that impairs visual acuity and postural stability, and affects cosme... | Acquired Pendular Nystagmus; Oscillopsia; Skull Vibration; Multiple Sclerosis | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
8 |
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Trial Design for an International Phase 2 Study of the Efficacy, Safety and Pharmacokinetics of the Anti-LINGO-1 Monoclonal Antibody, BIIB033, in Subjects With a First Episode of Acute Optic Neuritis | Acute optic neuritis (AON) is characterized by inflammatory injury to the optic nerve and is frequently the first manifestation of MS. In humans, ~20% of the nerve fiber layer is lost after an AON episode. LINGO-1 (leucine-rich repeats and immunoglobulin domain-containing neurite outgrowth inhibitor... | Acute Optic Neuritis; Multiple Sclerosis; Anti-LINGO-1 Monoclonal Antibody; BIIB033; Axonal Repair; Axonal Remyelination | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
9 |
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Normative Data and Conversion Equation for Spectral-Domain Optical Coherence Tomography in an International Healthy Control Cohort | | Adolescent; Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Multiple Sclerosis / diagnostic imaging; Nerve Fibers; Retinal Ganglion Cells; Tomography, Optical Coherence / methods; Young Adult | |
10 |
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Strabismus Surgery in Patients With Ocular Neuromyotonia: Potential Unmasking of the Condition and Effective Management Tool | | Adolescent; Adult; Color Vision; Color Vision Defects; Cross-Sectional Studies; Disease Progression; Female; Humans; Male; Middle Older people; Multiple Sclerosis; Nerve Fibers; Optic Nerve; Optic Neuritis; Retinal Ganglion Cells; Tomography, Optical Coherence; Visual Acuity; Young Adult | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
11 |
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Neuro-Ophthalmic Syndromes and Processing Speed in Multiple Sclerosis | | Adult; Auditory Perception; Cognition Disorders; Disability Evaluation; Female; Humans; Male; Multiple Sclerosis; Neuropsychological Tests; Psychomotor Performance; Spatial Processing; Syndrome; Vision Disorders | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
12 |
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Shortened Pattern Electroretinogram Latency and Impaired Autoregulatory Dynamics to Steady-State Stimuli in Patients With Multiple Sclerosis | | Adult; Axons / physiology; Electroretinography; Female; Homeostasis / physiology; Humans; Male; Middle Aged; Multiple Sclerosis / physiopathology; Optic Neuritis / physiopathology; Pattern Recognition, Visual; Retinal Ganglion Cells / physiology; Tomography, Optical Coherence; Visual Acuity / physio... | |
13 |
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Choriocapillaris Integrity in Relapsed Central Serous Chorioretinopathy in a Patient Treated With Fingolimod for Multiple Sclerosis: New Insights From Optical Coherence Tomography Angiography | | Adult; Central Serous Chorioretinopathy / diagnostic imaging; Central Serous Chorioretinopathy / physiopathology; Choroid / blood supply; Choroid / diagnostic imaging; Coloring Agents / administration & dosage; Fingolimod Hydrochloride / therapeutic use; Fluorescein Angiography; Humans; Immunosuppre... | |
14 |
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Association of Multiple Sclerosis and Intracranial Hypertension | | Adult; Female; Headache/complications; Humans; Intracranial Pressure; Middle Older people; Multiple Sclerosis/complications; Papilledema/complications; Pseudotumor Cerebri/etiology | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
15 |
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Is Multiple Sclerosis Associated With a Lower Intraocular Pressure? | | Adult; Older people; Female; Humans; Intraocular Pressure; Male; Middle Older people; Multiple Sclerosis; Ocular Hypotension; Retrospective Studies; Tonometry, Ocular; Young Adult | |
16 |
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Characterizing the Pathobiological Mechanisms of Binocular Acuity Summation versus Inhibition in MS: Central Adaptation or Not? | Research has shown that the 'fellow' unaffected eye, and its afferent visual pathway, in patients with unilateral optic neuritis, can exhibit physiologic changes which synchronize the arrival of visual information within the cortex. This 'temporal reorganization', if confirmed, would represent an im... | Afferent Visual Pathway; Unilateral Optic Neuritis; Adaptive Process; Temporal Reorganization; Multiple Sclerosis | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
17 |
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Multiple Sclerosis Therapy: Are We Ready for a One-Size-Fits-All Approach? | | Age of Onset; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Female; Humans; Immunologic Factors; Male; Multiple Sclerosis; Sex Factors | |
18 |
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Exploring the Oculomotor Effects of Sustained-Release Fampridine in Multiple Sclerosis Patients with Gait Impairment. (.pdf) | Fampridine is a potassium channel blocker that has been shown to suppress downbeat nystagmus effectively. Its effect upon other eye movement abnormalities is largely unknown. We sought to evaluate the immediate and late effects of sustained-release fampridine 10 mg twice a day upon eye movement abno... | Aminopyridines, Downbeat Nystagmus, Multiple Sclerosis, Internuclear Ophthalmoplegia, Video-Head Impulse Test | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
19 |
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The Shifting Landscape of Disease-Modifying Therapies for Relapsing Multiple Sclerosis | | Antibodies, Monoclonal, Humanized; Humans; Immunosuppressive Agents; Multiple Sclerosis, Relapsing-Remitting; Recurrence | |
20 |
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Multiple Sclerosis: B Cells Take Center Stage | | Antigens, CD20; B-Lymphocytes; Humans; Lymphocyte Depletion; Multiple Sclerosis; T-Lymphocyte Subsets | |
21 |
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Optico-Ghiashatic Arachnoiditis in Multiple Sclerosis | | Arachnoiditis; Neurologic Manifestations; Multiple Sclerosis; Scotoma | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
22 |
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New Onset Asymmetric Bilateral Visual Field Defect After Sequential Retrobulbar Neuritis in a Patient with Multiple Sclerosis | A 36 year old female patient presented with a sensomotor hemisymptomatic deficiendy and was hospitalized for work up and treatment. Magnetic resonance imaging (MRI) of the brain revealed multiple white matter lesions, compatible with the diagnosis of demyelinating disease such as multiple sclerosis. | Asymmetric Bilateral Visual Field Defect; Sequential Retrobulbar Neuritis; Multiple Sclerosis | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
23 |
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Pendular Horizontal Oscillations | Slideshow describing condition. | Ataxia; Bilateral Gaze Evoked Nystagmus; Gaze Evoked Horizontal Nystagmus; Horizontal Saccadic Dysmetria; Left Beating Nystagmus; Multiple Sclerosis; Obtrusive Saccades; Oscillopsia; Pendular Horizontal Oscillations; Primary Position Horizontal Nystagmus; Saccadic Dysmetria; Titubation | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
24 |
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Glial Fibrillary Acidic Protein Antibody - Another Antibody in the Multiple Sclerosis Diagnostic Mix | | Autoantibodies, Edema, Glial Fibrillary Acidic Protein, Humans, Meningoencephalitis, Multiple Sclerosis | |
25 |
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Autoimmune Optic Neuritis - Masquerading as MS | Optic neuritis in cases with subtle evidence of collagen vascular disease can be misdiagnosed as Multiple Sclerosis (MS). We diagnosed 9 cases with recurrent or progressive "autoimmune" optic neuritis, 4 of whom were referred with a diagnosis of MS. Anti-nuclear antibodies were definitely abnormal i... | Autoimmune Optic Neuritis; Multiple Sclerosis; Collagen Vascular Disease; Anti-Nuclear Antibodies | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |