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Title | Creator | History |
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The Relationship Between PDE-5 Inhibitors and NAION | Howard D. Pomeranz, MD | Sildenafil was first synthesized by pharmaceutical chemists working at Pfizer. It was initially studied for use in hypertension and angina. Phase I clinical trials suggested that the drug had little effect on angina but could induce penile erection. Sildenafil (Viagra®) was patented in 1996 and app... |
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Progressive Supranuclear Palsy | Richard Lindenberg | A 50-year old male with a several month history of conjugate gaze and stiffness of neck. History significant for an attempt on his wife's life Dx psychosis. |
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Occipital Lobe Lesions | John A. Wagner | N/A |
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Unilateral Intranuclear Ophthalmoplegia | Hardman, John | A 67-year old female with a 10-year history of rheumatoid arthiritis treated with steroids developed progressive neurologic deterioration over an 8-week period. |
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Reticulum Cell Sarcoma of Brain and Uveitis | Thomas P. Reams | A 65-year old male with a 4-year history of uveitis was found to have an isolated reticulum cell sarcoma of the brain. |
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Ocular Involvement with Dawson's Inclusion Body Encephalitis or SSPE (Subacute Sclerosing Panencephalitis) | Myron Yanoff | Two teenage girls died from a progressive neurological disease. |
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Cogan's Syndrome - Two Cases | Henry J. L. Van Dyk | Case 1: A 6-year old female with catarrhal conjunctivitis and impaired hearing. Case 2: A 23-year old female with episcleritis and Meniere syndrome. |
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Mystery Case | David G. Cogan, MD (1908-1993), Former Director of Ophthalmology, National Eye Institute | A 22-year old female with vertigo, diplopia and right sided headache. |
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Two Cases of Pituitary Apoplexy with Pathology | Thomas J. Walsh | N/A |
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Ectopic Pinealoma | Thomas R. Hedges | N/A |
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Intracanalicular Optic Nerve Glioma and Neurofibroma of the Choroid | George M. Howard | A 2-month old female with proptosis OS at birth together with two very large cafe au lait spots. |
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Cervical Intramedullary Ependymoma. Neurofibromatosis and Retinal Lesion | Alan M. Laties | A 24-year old male with sudden loss of hearing AD, vertigo and ataxia. Family history remarkable for father and brother Dx neurofibromatosis. |
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Neurofibroma of the Retina | Lois J. Martyn | A 13-year old female with asymptomatic loss of vision OD. |
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Grade III Astrocytoma of the Optic Nerve | Simmons Lessell, MD (1933 - 2016) | A 55-year old male with blurred vision and retro-orbital pain OS |
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Subacute Necrotizing Eneephalomyelopathy (Leigh's Disease) | Adam Borit | Two siblings born to parents who were first cousins with feeding difficulties and failure to thrive. They subswquently developed nystagmus, disconjugate eye movements and amaurosis. |
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Tolosa-Hunt Syndrome - Two Cases | Norman J. Schafz | The first patient is a thirty-eight year-old Negro female who presented with complaints of blurred vision and diplopia. |
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Post Adrenalectomy Pituitary Tumors | George B. Udvarhelyi | The hisologic characteristic of the pituitary tumors found in four patients who had undergone adrenalectomy for Cushing Syndrome. |
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Slowly Progressive Ischemic Optic Neuropathy | David L. Knox, MD, Wilmer Eye Institute | A 55-year old male with a 2-week history of progressive loss of the nasal field OS. |
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Ocular Ischemic Necrosis from Carotid Cavernous Fistula | H. Stanley Thompson, MD, University of Iowa | Case 1: A 42-year old female with a spontaneous carotid cavernous fistula on the left resultant from depressed skull fracture. Case 2: A 39-year old male with a right carotid cavernous fistula resultant from a parieto-occipital depressed skull fracture. |
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Optic Nerve Physiology and Anatomy | Anderson, Douglas R. | Electronmicroscopic elucidation of the function of astrocytes, oligodendrocytes, extracellular space and the significance of capillary glial relationships. |
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Dolicho-Ectatic Intracranial Arteries | Joel G. Sacks, MD, Tulane Medical Center | Dolicho-ectatic (elongated and distended) intracranial arteries were studied in 34 cases obtained at autopsy. |
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Progressive Ophthalmoplegia in a 15 month old girl with headaches | Richard Lindenberg | The patient had been well until about five months prior to admission when following a fall, her right eye was noted to wander intermittently. |
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Internuclear Ophthalmoplegia in a Child | David G. Cogan, MD (1908-1993), Former Director of Ophthalmology, National Eye Institute | A 4 1/2-year old male with a several month history of wandering right eye. |
24 |
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Ascending Polyneuritis and Ophthalmoplegia | Martin Lubow | A 62-year old male with lightheaded sensations attributed to flu-like symptoms. |
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Gaze palsy with head and shoulder spasms in a 15 year old boy | Guy McKhann | N/A |