Eccles Health Sciences Library
 
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1 Cupping in AIONLEEpathologies; LEEaioncuppingDr. Lee lectures medical students on the subject of cupping in AION.Optic Neuropathy; Giant Cell Arteritis; IschemiaNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
2 Is There a Racial Predilection Among Non-Arteritic Anterior Ischemic Optic Neuropathy Patients in the US?In the US, large retrospective series and recent clinical trials of non-arteritic anterior ischemic optic neuropathy (NAION) included mostly white patients, raising concern for the generalization of the results across all races and ethnicities. We aim to describe the race distribution in NAION, and ...Optic NeuropathyNeuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
3 Patient Portal: Non-Arteritic-Anterior Ischemic Optic Neuropathy (NAION)Non-arteritic anterior ischemic optic neuropathy (NAION or NA-AION) is caused by decreased blood flow to the front part of the optic nerve (optic disc). It causes optic nerve swelling and sudden vision loss. NAION typically affects one eye, although the other eye sometimes suffers similar loss month...Non-arteritic anterior ischemic optic neuropathy; NAION; NA-AION; Optic nerve; Optic disc; Ophthalmic arteryNeuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
4 Posterior Ischemic Optic Neuropathy (PION) - 2019LEEpion; LEEpathologies; IC-D1aii-posteriorDr. Lee lectures medical students on posterior ischemic optic neuropathy.Pathology; Ischemic/Strokes; NeuroanatomyNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
5 Nonartertic Anterior Ischemic Optic Neuropathy (NAION)LEEnaion; LEEpathologiesDr. Lee lectures on nonarteritic anterior ischemic optic neuropathy.Pathology; Ischemic/Strokes; Giant-Cell Arteritis; NeuroanatomyNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
6 Modulation of the Neuro-Glia-Vascular Niche by Plasma From Patients With Nonarteritic Anterior Ischemic Optic NeuropathyNonarteritic anterior ischemic optic neuropathy (NAION) is the most common acute optic neuropathy in those >50 years old, and about 20% patients develop second eye involvement. In this study, we ask whether plasma from NAION patients exhibit biological activity in vitro and in vivo.Optic NeuropathyNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
7 Hypotensive Optic NeuropathyLEEpathologies; LEEhypotensiveSummary: • Hypotension impacts the perfusion pressure of the optic nerve; o; Perfusion pressure of the optic nerve equals the mean arterial pressure minus the intraocular pressure (PP = MAP - IOP) o Anything that lowers MAP or raises IOP could cause ischemia to the optic nerve • Nocturnal hypote...Hypotension; Neuropathy; Intraocular PressureNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
8 Incipient NAIONLEEpathologies; LEEincipientnaionDr. Lee lectures medical students on incipient NAION.NAION; Disc Edema; SteroidsNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
9 NAION - Intra-Dialysis CountermeasuresLEEpathologies; LEEnaionintraSummary: Non-Arteritic Anterior Ischemic Neuropathy (NAION) • Ischemia to the optic nerve unrelated to arteritis • Etiologies: 1. MCC: Vasculopathies - hypertension, hyperlipidemia, smoking, sleep apnea, hypercoagulability 2. Hypotension - decreased mean arterial pressure (MAP) can lead to ische...NAION; Hypotension; DialysisNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
10 Blood Supply of the Optic NerveIC-A7avi-blood-supply-of-the-orbit-eye-and-optic-nerve; LEEanatomy; VBbloodsupplyoftheopticnerveDr. Lee lectures medical students on blood supply to the optic nerve.Blood Supply; Optic Nerve; IschemiaNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
11 Obstructive Sleep Apnea and Neuro-Ophthalmic Conditions (Video)IC-D1ai-anterior; NTLnomanifestationscomplications; Medical Knowledge; Patient Care; Practice-Based Learning and Improvement; Systems Based PracticeThere has been an emerging interest in the link between obstructive sleep apnea (OSA) and ocular health over the last decade. Though the evidence for OSA playing a role in cerebrovascular disease risk seems clear, the same cannot be said for optic neuropathies. The association between OSA and glauco...Obstructive Sleep Apnea; Non-arteritic Anterior Ischemic Optic Neuropathy; Glaucoma; Papilledema; Idiopathic Intracranial HypertensionNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
12 When Is It Not NAIONLEEpathologies; LEEnotnaion; LEEnaionSummary: • What is NAION? o Symptoms > Acute unilateral decreased visual acuity/visual field > RAPD in involved eye > Disc edema followed by sector atrophy > Small cup-to-disc ratio in fellow eye o Risk Factors > Elderly patient • Most common acute optic neuropathy in older patients > Vasculopat...NAIONNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
13 CRAO/NAIONLEEpathologies; LEEcrao; LEEnaion; IC-D1ai-anteriorSummary: CRAO/NAION: 1. Risk factors for both 2. Presentation a. Patient has vasculopathic factors i. Hypertension ii. Diabetes iii. Hyperlipidemia iv. Smoker b. Acute unilateral vision loss c. Ipsilateral RAPD (relative afferent papillary defect) d. This presentation could result from CRAO or NAION...CRAO; NAION; Vascular; EmbolicNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
14 Arteritic or Not? A Deep Learning System Can Accurately Distinguish Between Anterior Ischemic Optic Neuropathies on Ocular Fundus PhotographsThe urgent and accurate identification of the arteritic form of anterior ischemic optic neuropathy (AAION) from giant cell arteritis is of critical importance, often requiring complex and invasive interventions. The aim of this study was to evaluate the performance of a deep learning system (DLS) to...Optic Neuropathy; Vascular DisordersNeuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
15 Differential Diagnosis ListLEEexamfindings; LEEdifferentialSummary: • Differential diagnosis in neuro-ophthalmology can be approached from patient age and prevalence of disease • Mnemonic for differential diagnosis: o V-vascular o I-inflammatory/ischemic o T-trauma o A-anaplastic o M-metabolic o I-iatrogenic/idiopathic o N-neoplastic/nutritional • Pre...Differential; History; ExaminationNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
16 Giant Cell Arteritis (GCA)LEEpathologies; LEEgca; IC-E4bi-giant-cell-arteritis-temporal-arteritis; GVSgiantcellarteritistemporalarteritisSummary: • GCA is most common in elderly (age > 50) • Presenting symptom = headache anywhere in the distribution of the external carotid artery • Associated symptoms: scalp tenderness, jaw claudication, vision loss o Vision loss -Transient: amaurosis fugax -Permanent: anterior ischemic optic n...Headache; Claudication; Ischemia; GCA; TemporalNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
17 Ophthalmic Features and Prevalence of Systemic Disorders in Participants in the QRK07 NAION Treatment TrialThe QRK207 study was the first multi-country treatment trial for patients with acute nonarteritic anterior ischemic optic neuropathy (NAION). We assessed ophthalmic and systemic factors associated with an increased risk of NAION and examined if they varied across countries.Optic Neuropathy; Vascular DisordersNeuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
18 Amiodarone Optic NeuropathyLEEpathologies; LEEamiodaroneSummary •Amiodarone optic neuropathy o Amiodarone is an anti-arrhythmic used by cardiology -Amiodarone produces a toxic optic neuropathy that looks similar to non-arteritic anterior ischemic optic neuropathy (NAION) o Differentiating features between NAION and Amiodarone Optic Neuropathy -NAION �...Amiodarone; NAION; Disc Edema; KeratopathyNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
19 Giant Cell Arteritis (GCA) Unusual PresentationsLEEgca; LEEgcaunusual; LEEpathologiesDr. Lee lectures medical students on giant cell arteritis (GCA).Arteritis; Neuropathy; VasculitisNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
20 The Relationship Between PDE-5 Inhibitors and NAIONErectile Dysfunction Drug; Non-Arteritic Anterior Ischemic Optic Neuropathy; Phosphodiesterase 5 (PDE-5) Inhibitor; Pfizer; SildenafilNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
21 OCTA: What Can it Tell Me and How to Use ItOptical coherence tomography angiography (OCTA) compares the decorrelation signal (differences in the backscattered OCT light signal amplitude) between sequential OCT B-scans taken at a single cross section(motion contrast). Since only blood flow would be expected to create movement and differences ...Optical Coherence Tomography Angiography (OCTA); Swept Source OCTA; Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION); Non-Ischemic Optic Disc Edema; Optic Disc DrusenNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
22 Optic Nerve Sheath FenestrationLEEpathologies; LEEfenestrationDr. Lee lectures medical students on optic nerve sheath fenestration.Optic Nerve Sheath Fenestration; Papilledema; Idiopathic Intracranial Hypertension (IIH); Non-arteritic Anterior Ischemic Optic NeuropathyNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
23 Foster-Kennedy syndrome vs Pseudo-Foster-Kennedy syndromeLEEpathologies; LEEfosterkennedy; IC-D1ciii1-optic-nerve-tumors-dianosis-and-therapy; IC-D2bii-skull-base-lesionsSummary • True Foster-Kennedy syndrome o Presentation -Optic disc edema in one eye + optic atrophy in the other eye o Cause -Tumor pressing on ipsilateral optic nerve, causing optic atrophy in one eye -Increased intracranial pressure from tumor causes papilledema in the other eye -Tumor is most co...Tumor; Intracranial Pressure; Atrophy; PapilledemaNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
24 Epigenetic Reprogramming- A Novel Gene Therapy to Rejuvenate Injury-Induced Dysfunction of Retinal Ganglion Cells in Optic NeuropathiesNAION (Non-Arteritic Anterior Ischemic Optic Neuropathy) and glaucoma are optic neuropathies with different pathophysiology but a common endpoint, the apoptosis of retinal ganglion cells (RGCs).Optic Nerve Trauma and Treatment; Optic NeuropathyNeuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
25 The Relationship Between PDE-5 Inhibitors and NAION (Video)GVSsildenafil; IC-D1ai-anterior; Medical Knowledge; Patient Care; Practice-Based Learning and ImprovementIntroduction to the History of Erectile Dysfunction Drug Development and Mechanism of Action: Sildenafil was first synthesized by pharmaceutical chemists working at Pfizer. It was initially studied for use in hypertension and angina. Phase I clinical trials suggested that the drug had little effect ...Erectile Dysfunction Drug; Non-Arteritic Anterior Ischemic Optic Neuropathy; Phosphodiesterase 5 (PDE-5) Inhibitor; Pfizer; SildenafilNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
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