Filters: Subject:"Physiology" School Or College:"School of Medicine" Publication Type:"thesis" Collection:"ir_etd" Format:"application/pdf"
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| Title | Author | Subject | Description | Date | ||
|---|---|---|---|---|---|---|
| 1 |  | Biochemical conversion of progesterone to orchic androgens | Martin, Robert Packard | Physiology; Biosynthesis | 1. A new system of chromatography has been described which allows resolution of the less polar steroids" such as cholesterol and congeners. It is a reversed phase system utilizing odorless kerosene as the stationary phase, and 60 per cent aqueous n-propanol as the developing phase. It has proved ... | 1956-06 |
| 2 |  | Control of cardiac output studied with computer techniques. | Topham, William Sanford | Anatomy; Physiology | This thesis concludes with an analog model which has limitations but provides a solution to the control of cardiac output. This solution is not unique and as a model is used to predict the response to different types of stimulation, changes, will be made. However, a basic model has been presented ... | 2008-02 |
| 3 |  | Effect of cortisol and deoxycorticosterone acetate on brain amino acid and electrolyte metabolism | Vernadakis, Antonia | Physiology | Numerous studies have been carried out on the adrenocortical steroids during the last fifteen years. The effects of adrenocortical steroids on carbohydrate, fat, electrolyte and protein metabolism of various tissues and organs, and the specificity of these hormonal actions continue to be investigat... | 1957-06 |
| 4 |  | Effect of uracil incorporation on the precision of HIV-1 (+)-strand DNA initiation | Chen, Xin | Physiology; Genetics | Retroviruses have means to limit the accumulation of uracil in DNA strands, suggesting that uracil affects one or more steps in the viral life cycle. In this work, the effects of uracilated DNA were investigated in biochemical assays of (-)-strand DNA synthesis, RNase H activity and (+)-strand synt... | 2001-05 |
| 5 |  | The effects of adrenal corticosteroids on oxygen utilization in rats | Roosevelt, Theodore Steven | Physiology; Anatomy | 1. Sham-adrenalectomized and cortisol injected adrenalectomized rats survived exposure to a hypoxic (5% oxygen) atmosphere significantly longer than did adrenalectomized control rats. 2. The difference in survival times between rates with and without corticosteroids was not due to the absence of th... | 1972-06 |
| 6 |  | The effects of commonly used antibiotic medications on the efficacy of tyrosine kinase inhibitors in Philadelphia Chromosome Positive Leukemia | Zhao, Brooke Marie | Pharmacology; Physiology | The main purpose of this thesis project is to develop and validate a high-throughput protocol to test drug-drug interactions. As a model, tyrosine kinase inhibitors were tested with commonly used antibiotics in Philadelphia chromosome positive leukemia patients. Tyrosine kinase inhibitors (TKI's), s... | 2017 |
| 7 |  | Effects of NOx compounds on heme-containing enzymes | Lu, Yanxiang | Physiology; Drug Effects | Nitric oxide (NO) has been shown to be involved in many important biological processes. The biochemical pathways of these processes share two common features: the enzymatic synthesis of NO from L-arginine and the formation of an iron-nitrosyl complex in a target (heme) protein to evoke the function ... | 1996-06 |
| 8 |  | Health effects among refrigeration repair workers exposed to fluorocarbons. | Campbell, David Douglas. | Neuropathy; Refigeration; Physiology | Refrigeration repair workers may be intermittently exposed to fluorocarbons and their thermal decomposition products. An index case of peripheral neuropathy (distal axonopathy) in a commercial refrigeration repairman prompted an epidemiologic investigation of the health of refrigeration repair work... | 1983-12 |
| 9 |  | Identification of proteomic changes induced in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma in response to the heat shock protein 90 inhibitor geldanamycin | Schumacher, Jonathan A. | Physiology | Anaplastic large cell lymphoma (ALCL) is a subset of non-Hodgkin lymphoma that commonly express the t(2;5)(p23;q35) chromosomal translocation, resulting in overexpression of the nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) oncoprotein. ALK harbors a cytoplasmic tyrosine kinase domain that has ... | 2005-12 |
| 10 |  | Influence of certain hormones on nucleic acids and metabolism by lymphocytes | Brinck-Johnsen, Truls | Physiology; Metabolism | In the present investigation the uptake and prolonged retention of adenine-8-C-14 by lymphatic tissue of mice was demonstrated. The experiments bring support to the idea that the nucleic acids of dead lymphocytes are re-utilized during heteroplastic lymphocytopoiesis. Tumor tissue has been shown t... | 1959-06 |
| 11 |  | The metabolism of intravenous testosterone. | West, Charles Donald | Physiology; Metablism; Biochemistry | The fate of testosterone administered intravenously in experimental animals has been investigated. The injected testosterone diffused rapidly from the circulation into various tissues of the body, the highest concentrations being found in fat. The testosterone was apparently not metabolized in the... | 1951-06 |
| 12 |  | Monocyte nonspecific esterase: a technique for quantifying activity | Simonian, Yasmen | Analysis; Physiology | During a study comparing the results of leukocyte differential counts obtained from the Hemalog-D with those obtained by manual techniques, discrepancies in monocyte counts were observed in patients with lymphomas. It was postulated that these patients might have monocyte nonspecific esterase (MNS... | 1981-12 |
| 13 |  | Progestational hormone in human placenta | Noall, Matthew Wilcox | Progestational Hormones; Physiology | Progesterone has been isolated from human placental tissue in a yield of approximately one part per million parts of tissue. The initial step involved digesting the tissue in a sodium hydroxide solution. The alkaline digestion partially liquefied the ground tissue, liberated lipids from lipoprotei... | 1952 |
| 14 |  | Role for type 1 interferons in the exclusion of B cells from microphthalmic marrow | Roundy, Kirstin Mae | Physiology; IFN-beta-Mediated | Previous studies demonstrated an increase RANKL (receptor activator of NF-kB ligand) mRNA and a deficiency of B cells in the bone marrow of the microphthalmic (mi)mouse. We hypothesized that the overexpression of RANKL is a bone hemostatatic response to stimulate osteoclasts to degrade bone and rel... | 2004-05 |
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