Eccles Health Sciences Library
 
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26 Multiple Sclerosis Follow UpDr. Lee lectures medical students on the subject of following up on with a patient with multiple sclerosis.Multiple Sclerosis; Fingolimod; FAMENeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
27 Uhthoff PhenomenonSummary: • Uhthoff phenomenon overview: o Symptoms include vision loss caused by heat, exertion, or exercise o Not necessarily just poor vision, can also lead to numbness or weakness o Seen in people with multiple sclerosis (MS) • Pathophysiology o Seen in people with MS since they rely on regul...Multiple Sclerosis; Vision LossNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
28 Visual Dysfunction in MS Is Associated with Abnormalities in Normal-Appearing Gray and White MatterMultiple Sclerosis; MRI; VisionNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
29 Visual Function and Disease Phenotype in Multiple SclerosisVisual function is one of the most common and disabling manifestations of MS. While other clinical dimensions of neurologic function, such as those in the MS Functional Composite (MSFC = Timed 25-Foot Walk, 9-Hole Peg Test, and Paced Auditory Serial Addition Test), have been demonstrated to be valid...vision; multiple sclerosis; phenotypeNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
30 Walsh & Hoyt: Idiopathic and Primary Demyelinating Optic NeuritisDespite remarkable advances in neuroimaging and electrophysiologic testing, the diagnosis of optic neuritis remains basically a clinical one.Optic Neuritis; Multiple SclerosisNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
31 Walsh & Hoyt: Multiple SclerosisMultiple sclerosis is one of the most common causes of neurologic and visual disability among young and middleaged adults. The disorder affects over 1 million people worldwide, but is particularly common in the United States, where approximately 300,000 persons are affected. Seventy-three percent of...Demyelinating Diseases; Multiple SclerosisNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
32 Extra-Axonal Ocular Damage Quantification by Multifocal Electroretinography in Chronic Progressive Multiple SclerosisImmune mechanisms in multiple sclerosis (MS) are more complex than previously thought, are mediated by both T and B cells, and produce demyelination and axonal pathology in both grey and white matter.1 Previous studies have focused on optical coherence tomography (OCT) measurements of retinal nerve ...Multiple Sclerosis; Chronic Progressive Multiple Sclerosis; Optical Coherence Tomography; Multifocal ElectroretinogramNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
33 Starting and Switching Multiple Sclerosis TherapyWhen to start or switch MS therapy is a hotly debated topic. In this talk, we will examine the issues surrounding the initiation of therapy for those patients with the clinically isolated syndrome, the radiologically isolated syndrome and benign MS.Multiple Sclerosis (MS); Treatment; Benign MS; Radiologically Isolated Syndrome; Clinically Isolated Syndrome (CIS); Relationships Between Optic Neuritis and Multiple Sclerosis; Multiple Sclerosis Diagnosis; Multiple Sclerosis Treatment Strategies; Vision Assessment in Multiple SclerosisNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
34 The Optic Nerve: "Tip of the Iceberg" of DemyelinationMultiple sclerosis (MS) and neuromyelitis optica (NMO) are distinct immune-mediated inflammatory conditions that characteristically attack the optic nerve, brain and spinal cord. Associated optic nerve demyelination and axonal loss lead to a range of visual complaints and disabilities that may be th...Optic Neuritis; Multiple Sclerosis; Neuromyelitis Optica; Optical Coherence Tomography; Optic Atrophy; Idiopathic Optic Neuritis; Relationships Between Optic Neuritis and Multiple Sclerosis; Multiple Sclerosis Diagnosis; Multiple Sclerosis Treatment Strategies; Vision Assessment in Multiple Sclerosi...Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
35 Neuromyelitis Optica Spectrum Disorders: Diagnosis and TreatmentThe last decade has witnessed rapid developments in the clinical understanding and scientific foundation of neuromyelitis optica (NMO).Neuromyelitis Optica; Optic Neuritis; Transverse Myelitis; Aquaporin-4; Relationships Between Optic Neuritis and Multiple Sclerosis; Multiple Sclerosis Diagnosis; Multiple Sclerosis Treatment Strategies; Vision Assessment in Multiple SclerosisNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
36 "Oh, You Have Metastatic Cancer"Hemianopsia; Multiple Sclerosis; Demyelinating DiseasesNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
37 "Oh, You Have Metastatic Cancer" (PowerPoint)Hemianopsia; Multiple Sclerosis; Demyelinating DiseasesNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
38 "Oh, You Have Metastatic Cancer" (Presentation Video)Hemianopsia; Multiple Sclerosis; Demyelinating DiseasesNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
39 A Progressive Neurological Disorder with Ring Enhancing CT LesionMultiple Sclerosis; Demyelinating Diseases; HemianopsiaNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
40 Analysis of the Ten-Year Evaluation of the ONTT PatientsOptic Neuritis Treatment Trial (ONTT) patients have been followed for > 10 years in order to evaluate long-termvision and neurological status.optic neuritis; multiple sclerosis; EDSSNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
41 Comparison of Multifocal Objective Pupil Perimetry and MRI in Multiple SclerosisMagnetic resonance imaging (MRI) is widely used as a surrogate marker in the assessment of patients with multiple sclerosis (MS). An alternative to MRI which was equally informative but cheaper, more patient-friendly, and more easily accessible would be highly desirable. Multifocal objective pupil p...multiple sclerosis; pupillometry; MRI; investigationNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
42 Homonymous Hemianopia in a Young WomanHemianopsia; Dysarthria; Multiple Sclerosis; ParesisNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
43 Immunoglobin Heavy-Chain Repertoire Bias and the Risk of Demyelinating Disease in Isolated Optic NeuritisFor individuals with optic neuritis (ON) or a clinically isolated syndrome (CIS), longitudinal studies demonstrate that the risk of developing multiple sclerosis (CDMS) rises steadily with time. Inflammation, as measured by MRI lesion load or cerebrospinal fluid (CSF) oligoclonal banding, may be use...optic neuritis, multiple sclerosis, immunoglobulinNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
44 Management of Acute Optic Neuritis : Survey of Ophthalmologists and Neurologists in the South-East United StatesRecent clinical trials have emphasized the natural history of acute optic neuritis, its association with multiple sclerosis (MS) and its management. However, the current management of the acute optic neuritis patient by neurologists and ophthalmologists varies widely and remains debated.Survey, Optic neuritis, Multiple sclerosisNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
45 Ophthalmic evaluations in clinical studies of fingolimod (FTY720) in multiple sclerosis (MS)Fingolimod is a sphingosine 1-phosphate receptor modulator used to treat relapsing MS. The results of ophthalmic evaluations during clinical studies of fingolimod in patients with MS are reported.multiple sclerosis; fingolimod; ophthalmic evaluationNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
46 Opsoclonus and Ocular Flutter in Multiple SclerosisOpsoclonus and ocular flutter almost always occur as part of either a parainfectious or paraneoplastic syndrome. Toxic causes are also described. Most other etiologies are exemplified by single or only a few cases. The visible pathology in autopsied cases is very variable, and different pathophysiol...opsoclonus; ocular flutter; multiple sclerosisNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
47 Walsh & Hoyt: DiagnosisThe diagnosis of clinically definite MS has traditionally required clinical documentation of two discrete demyelinating events separated in space and time. This clinical diagnosis is then supported by the results of neuroimaging and laboratory studies. The current diagnostic criteria for MS, develop...Demyelinating Diseases; Multiple Sclerosis; DiagnosisNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
48 Walsh & Hoyt: EpidemiologyEpidemiologic studies of MS must now be interpreted in the context of the recent development of new diagnostic criteria. In the past, such studies were limited by a number of methodologic difficulties. In the first place, whereas diagnostic criteria for MS have been refined over time, the clinical d...Demyelinating Diseases; Multiple Sclerosis; EpidemiologyNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
49 Walsh & Hoyt: PathogenesisDemyelination associated with inflammation and limited remyelination are major pathologic features of MS, but axonal transection is also a prominent and irreversible component. Evidence of alteration of the bloodbrain barrier occurs concomitantly with these pathologic changes. Computed tomographic (...Demyelinating Diseases; Multiple Sclerosis; PathogenesisNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
50 Walsh & Hoyt: PathologyThe gross pathology in patients with chronic MS is typical. In the majority of cases, the brain shows no obvious abnormalities, although the leptomeninges may appear thickened and the brain may appear covered with a cortical gray mantle. There may be a particularly prominent arachnoiditis in the reg...Demyelinating Diseases; Multiple Sclerosis; PathologyNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
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