Eccles Health Sciences Library
 
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26 Effect of Prostaglandin Analogs on Cerebrospinal Fluid Reabsorption Via Nasal MucosaCerebrospinal fluid (CSF) outflow has been demonstrated along nasal lymphatics via olfactory nerve projections; flow may be increased by stimulating lymphatic contractility using agents such as noradrenaline and the thromboxane A2 analog U46619. Lymphatics elsewhere in the body show increased contra...High Intracranial Pressure/headache; Pseudotumor CerebriNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
27 Elevated Intracranial Pressures and Papilledema in a Mouse Model of Glucocorticoid Induced Adrenal InsufficiencyMechanisms underlying elevated intracranial pressure (ICP) in idiopathic intracranial hypertension (IIH) are poorly understood. Several recent cases have implied adrenal function to contribute to the pathophysiology of IIH, but no studies have examined this relationship to date. Using a mouse model ...Pseudotumor Cerebri; High Intracranial Pressure/Headache; Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc)Neuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
28 Headache Management in IIHHeadache is a common symptom when patients initially develop idiopathic intracranial hypertension (IIH) or intracranial hypertension from a secondary cause. While the headache often improves with intracranial pressure lowering therapies, it becomes a chronic problem and a long-term management challe...Idiopathic Intracranial Hypertension; Headache; Medication Overuse Headache; Pseudotumor CerebriNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
29 Pseudo-Pseudotumor Cerebri?A 23-year-old female to male transgender patient (BMI=30) on testosterone therapy presented to the urgent clinic with bilateral disc swelling and preserved optic disc function (Figure 1a-1b). He had a 5 day history of general malaise. Past medical history was pertinent for scoliosis surgery at age 1...Intracranial Tumors; Increased Intracranial Pressure; Vision Loss; Complications of CancersNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
30 Retinal Vessel Dynamics as a Surrogate Marker for Intracranial Pressure in Idiopathic Intracranial HypertensionMonitoring intracranial pressure (ICP) is hard to achieve but desirable for successful management of idiopathic intracranial hypertension (IIH). Diagnosis is primarily based on lumbar puncture (LP) opening pressure (OP) and there is an unmet need for a non-invasive and reliable method for long term ...High Intracranial Pressure/Headache; Retina; Pseudotumor CerebriNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
31 Significance of Incidental Imaging Signs of Intracranial Hypertension with Corresponding Fundus Photography: A Prospective StudyMRI signs suggesting intracranial hypertension are common in patients with idiopathic intracranial hypertension (IIH), but are also incidentally detected in asymptomatic patients and those with primary headache syndromes, prompting neuro-ophthalmology consultations and investigations.1-3 We aimed to...High Intracranial Pressure/Headache; Neuroimaging; Pseudotumor CerebriNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
32 Artificial Intelligence Reveals Disease-Specific Quantifiable Visual Field Defects in Idiopathic Intracranial HypertensionAssessing regional visual field (VF) changes typically requires qualitative expert or subjective analysis. Archetypal analysis (AA), a type of unsupervised machine learning, has been used to identify and monitor patterns of VF loss in glaucoma. AA has not beenapplied to non-glaucomatous optic neurop...Optic Neuropathy; Pseudotumor Cerebri; Visual FieldsNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
33 Impact of Glucose on Mitochondrial Function in a Brain Slice Model of Headache MechanismsIdiopathic intracranial hypertension (IIH) is a condition of raised intracranial pressure that features debilitating headaches with migraine-like characteristics. Cortical Spreading Depression (CSD), a propagating wave of depolarisation across the cerebral cortex, proposed to activate trigeminal ner...High Intracranial Pressure/Headache; Pseudotumor CerebriNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
34 How Much Weight Loss is Required to Reduce Intracranial Pressure in Idiopathic Intracranial Hypertension?The IIH:WT randomised trial established that weight loss through bariatric surgery significantly reduced intracranial pressure (ICP) at 12 and 24 months as compared to a community weight management intervention (CWI). This study aimed to evaluate the amount of weight loss required to reduce ICP in i...High Intracranial Pressure/headache; Pseudotumor CerebriNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
35 Referral Patterns to Neuro-Ophthalmology for Presumptive Idiopathic Intracranial Hypertension (IIH) Based on Isolated Neuroimaging FindingsRadiologic findings of intracranial hypertension (RAD-IH) are common in IIH patients. Paralleling the increasing rates of obesity, the burden of IIH is growing. Requests for urgent neuro-ophthalmology consultation for "IIH?" in patients incidentally detected to have RAD-IH are increasing, with many ...High Intracranial Pressure/Headache; Pseudotumor Cerebri; NeuroimagingNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
36 Weight Loss in IIHIt has been well known that IIH is associated with obesity. Weight gain is considered a risk factor for disease onset and recurrences. Weight loss has been well documented in several case series to be associated with improvement in symptoms and signs and to be associated with lowering of intracrania...Idiopathic Intracranial Hypertension; Pseudotumor Cerebri; Weight Loss; Treatment; Idiopathic Intracranial Hypertension Treatment TrialNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
37 Weight Loss in IIHIC-G4a-counseling-for-weight-lossIt has been well known that IIH is associated with obesity. Weight gain is considered a risk factor for disease onset and recurrences. Weight loss has been well documented in several case series to be associated with improvement in symptoms and signs and to be associated with lowering of intracrania...Idiopathic Intracranial Hypertension; Pseudotumor Cerebri; Weight Loss; Treatment; Idiopathic Intracranial Hypertension Treatment TrialNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
38 Can We Repeat an ONSF?Idiopathic intracranial hypertension (IIH) is a growing problem associated with headaches but most importantly to ophthalmologists vision loss. For patients with mild to moderate vision loss, medical management is typically sufficient for control of symptoms and resolution of papilledema. However, i...Optic Nerve Sheath Fenestration; Optic Nerve Sheath Decompression; Papilledema; Idiopathic Intracranial Hypertension; Cerebrospinal FluidNeuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
39 Endovascular Venous Stenting for Idiopathic Intracranial Hypertension (IIH)IC-E12ciii-neuro-endovascular-proceduresVenous sinus stenosis has been observed in patients with idiopathic intracranial hypertension (IIH) over the last two decades. Uncertainty remains as to whether this stenosis is the result or cause of intracranial hypertension in certain patients with the disease or whether it may be both. The assoc...Idiopathic Intracranial Hypertension; Venous Sinus Stenosis; Venous Stenting; Venous Sinus Hypertension; Pseudotumor CerebriNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
40 Pseudo Pseudo Pseudo Tumor Cerebri (Presentation Video)Pseudotumor Cerebri; Sinus Thrombosis, Intracranial; Central Nervous System Vascular Malformations; Thrombophilia; Papilledema; Intracranial Arteriovenous Malformations; Migraine DisordersNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
41 Idiopathic Intracranial Hypertension Pseudotumor CerebriLEEiihpseudotumor; LEEpathologies; LEEsequential; LEEsequeniih; LEEsequeniih1; LEEiih; IC-D1i-papilladema-secondary-to-raised-intracranial-pressureDr. Lee lectures medical students on idiopathic intracranial hypertension.Pathologies; PseudotumorNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
42 Empty SellaLEEexamfindings; LEEemptysellaSummary: • Primary empty sella is found incidentally and normal in 15% of the population • Secondary empty sella causes can cause visual field defects of the optic chiasm (ex. Bitemporal hemianopsia) o Can be intrasellar or suprasellar lesions o Common causes: > Transsphenoidal surgery to remove...Empty Sella; Visual Field Defects; Sellar LesionsNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
43 Deep Learning Can Accurately Distinguish Between True Papilledema and Optic Disc Drusen on Fundus PhotographsIdentification of true papilledema due to raised intracranial pressure requires high neuro-ophthalmic expertise and expensive ancillary testing. Its ophthalmoscopic diagnosis can be easily mistaken with false papilledema due to optic disc drusen (ODD), especially if the latter are buried within the ...High Intracranial Pressure/Headache; Optic Neuropathy; Pseudotumor Cerebri; Vascular DisordersNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
44 Ocular Deformities in Spaceflight-Associated Neuro-Ocular Syndrome and Idiopathic Intracranial Hypertension"Spaceflight-Associated Neuro-Ocular Syndrome (SANS)" shares several clinical elements with Idiopathic Intracranial-Hypertension (IIH), namely disc edema, globe-flattening, hyperopic-shift, and choroidal folds. In IIH, globe-flattening is caused by increased intracranial pressure (ICP); the cause in...Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc); Pseudotumor Cerebri; High Intracranial Pressure/Headache; MiscellaneousNeuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
45 Under PressureParaneoplastic Disorders, Polyneuropathy, Papilledema, Optic Nerve Sheath FenestrationNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
46 Lost in the SauceA 41-year-old male was referred to neuro-ophthalmology for "pseudotumor cerebri and hypertensive retinopathy" and decreased vision. Three months prior the examination, the patient reported a fairly rapid painless decline in the vision in both eyes over a week. He also reported heavy polysubstance ab...Optic Neuropathy; Optic Atrophy; Metabolic Disease; Neurologic Disorders; Vision Loss BinocularNeuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
47 Lateralizing Cranial Nerve LesionsLEEnervelesions; LEEpathologiesSummary: •Lateralizing findings: o problem on right or left side o Cranial nerves: > mostly ipsilateral > do not cross > palsy side is the same side of the lesion o Important cranial nerves that will be discussed: > Olfactory: ipsilateral-ipsilesional > Cranial nerve: prechiasmal > Cranial nerve 3...Cranial Nerves; Lateralizing FindingNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
48 Detection of Papilledema on Non-Mydriatic Ocular Fundus Photography In the Emergency Department: Application of the BONSAI Deep Learning System (DLS) To the FOTO-ED StudyThe FOTO-ED studies showed that ED providers (EDPs) poorly recognized relevant ocular funduscopic findings in patients presenting to the ED with headaches, acute neurologic findings, severe hypertension or visual loss, using direct ophthalmoscopy [0% correctly identified] or on non-mydriatic fundus ...Pseudotumor Cerebri; Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc)Neuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
49 IIH and Metabolic SyndromeLEEpathologies; LEEiihDr. Lee lectures medical students on IIH and its connection to metabolic syndrome.Idiopathic Intracranial Hypertension (IIH); Polycystic Ovarian Syndrome; MetabolicNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
50 Arteriovenous FistulaLEEanatomy; LEEarteriovenousSummary: • Arteriovenous fistulas (AVFs) and arteriovenous malformations (AVMs) have similar pathophysiology and similar appearance radiographically but are slightly different o AVM: congenital problem involving a direct artery to vein connection with a nidus malformation; big tangle of blood vess...Arteriovenous Fistula; Arteriovenous MalformationsNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
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