The Health Education Assets Library (HEAL) is a collection of over 22,000 freely available digital materials for health sciences education. The collection is now housed at the University of Utah J. Willard Marriott Digital Library.
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Filters: Collection: ehsl_heal
| Title | Description | Subject | Collection | ||
|---|---|---|---|---|---|
| 501 |
 |
Small, medium and large lymphocytes in blood smear (human) | Stain: May-Grnwald-Giemsa (MGG). The picture shows three activation stages of lymphocytes as (1) small, (2) medium and (3) large lymphocytes. In that range the nucleus becomes less condensed and more transparent, while the amount of cytoplasm increases. The large lymphocyte also contains some granul... | Poja Histology Collection - Blood & Bone Marrow Subset | |
| 502 |
 |
Survey and detail of a peripheral blood smear contaminated with endothelial cells (human) | Stain: May-Grnwald-Giemsa (MGG). Survey (A) and details (B) show aggregates of elongated cells with a large nucleus, mostly situated at the end of a smear between the erythrocytes and granulocytes. These endothelial cells are contaminants derived from blood vessels during puncture. | Poja Histology Collection - Blood & Bone Marrow Subset | |
| 503 |
 |
Survey and detail of bone marrow section (human) | Stain: modified hematoxylin and eosin (A, B). The bone marrow consists of bone trabecles or crests (1) covered with osteoclasts and osteoblasts. Between the trabecles bone marrow parenchym (2) consisting of progenitor cells, reticular cells and fat cells (3). Numerous capillaries (B, 4) and enlarged... | Poja Histology Collection - Blood & Bone Marrow Subset | |
| 504 |
 |
Survey of bone marrow (bone marrow, rabbit) | Electron microscopy. Within the loose reticular tissue a great variety of different stages of young erythrocytes (3, 4) as well as of young granulocytes (5) is present. (2) indicates reticular cells and (2b) phagocytizing reticular cells. (1) fat cells (adipocytes); (6) myeloid cell; (7) capillary. | Poja Histology Collection - Blood & Bone Marrow Subset | |
| 505 |
 |
Survey of bone marrow section (human) | Stain: modified hematoxylin and eosin. In this survey the white spots (1) are fat cells. The marrow is well filled with cells of erythropoietic and myelopoietic series. The very large cells are usually megakaryocytes. Cells with very dark condensed nuclei belong mostly to the erythropoietic series. | Poja Histology Collection - Blood & Bone Marrow Subset | |
| 506 |
 |
Survey of megakaryocytes (peripheral blood, human) | Electron microscopy. In a section of a so-called buffy coat collected from peripheral blood two huge polyploid megakaryocytes (1) (diameter up to 160 μm) are present. Note the dark granules in the future platelets. (2) erythroblasts; (3) reticulocytes and erythrocytes; (4, 5) monocytes. The arrows ... | Poja Histology Collection - Blood & Bone Marrow Subset | |
| 507 |
 |
Three basophilic erythroblasts in bone marrow smear (human) | Stain: May-Grnwald-Giemsa (MGG). Three basophilic erythroblasts (1) with intense blue stained cytoplasm, and some so called ears or cytoplasmic projections (arrows). Chromatin strands are thicker than in the proerythroblast. Generally no nucleoli are seen. (2) Damaged or smudged eosinophilic myelocy... | Poja Histology Collection - Blood & Bone Marrow Subset | |
| 508 |
 |
Toxic granulation and vacuolation in neutrophilic myelocytes in peripheral blood smear (human) | Stain: May-Grnwald-Giemsa (MGG). The myelocyte (1) and the metamyelocyte (2) show toxic granulation and vacuolation and cytoplasmic swelling. Vacuoles may represent the terminal stage of autophagocytosis. Granules may burst and their contents undergo autophagocytosis in a number of pathologic condit... | Poja Histology Collection - Blood & Bone Marrow Subset | |
| 509 |
 |
Toxic granulation and vacuolization in neutrophilic myelocytes in peripheral blood smear (human) | Stain: May-Grnwald-Giemsa (MGG). The myelocyte (1) and the metamyelocyte (2) show toxic granulation, vacuolisation and cytoplasmic swelling. Toxic granulation is characterized by violet-purple granules of varying size in the cytoplasm; generally admixed with normal pink granules. The phenomenon occu... | Poja Histology Collection - Blood & Bone Marrow Subset | |
| 510 |
 |
Vacuolar degeneration of neutrophils in peripheral blood smear (human) | Stain: May-Grnwald-Giemsa (MGG). Toxic degeneration of neutrophil resulting in vacuolization of cytoplasm (1); cell with beginning vacuolization (2). | Poja Histology Collection - Blood & Bone Marrow Subset | |
| 511 |
 |
: Localization of ED3-positive subpopulation of macrophages in spleen (rat) | Stain: Immunohistochemistry of Vector red staining using the antibody ED3. The survey in (A) shows that the ED3-positive macrophages are found as a ring in the marginal zone border, as well as spread in the red pulp area (2). The cells are sometimes referred as marginal metallophilic macrophages. T... | metallophilic macrophages; ED3 antibody; marginal zone | Poja Histology Collection - Lymphatic Tissues and Organs Subset |
| 512 |
 |
: Lymph node (human) | Stain: Azan. Specialized venules (1) or so-called high endothelial venules (HEV) are here located in the paracortical area (4) close to the lymphatic follicle (2+3). The HEVs are lined by cuboidal or columnar endothelial cells that possess specific homing receptors for antigen-primed B- and T ly... | paracortex; high endothelial venule (HEV); germinal center | Poja Histology Collection - Lymphatic Tissues and Organs Subset |
| 513 |
 |
: Lymph node (rat) | Electron microscopy. A low magnification of a part of the medulla showing medullary cords surrounded by labyrinthine medullary sinus (*). In this picture the medullar cord runs from left bottom corner to right top corner, and is lined by flat reticular cell types. Within the cord one finds a star-sh... | medulla; electron microscopy; sinusoid | Poja Histology Collection - Lymphatic Tissues and Organs Subset |
| 514 |
 |
Accidental involution of thymus (mouse, malaria infection) | Stain: Hematoxylin & eosin. Due to the infection with malarial parasites (Plasmodium berghei in mice) a steroid-related involution of the thymus is induced in mice within 14 days. A: normal thymus with cortex (2) and medulla (1). B: There is still a quite large remnant of the original thymus tissue ... | malaria infection; thymus involution; Plasmodium berghei; lymphoid tissue | Poja Histology Collection - Lymphatic Tissues and Organs Subset |
| 515 |
 |
Afferent lymph vessel in lymph node (human) | Stain: Azan. Left (A) and right (B): part of the cortex of a lymph node with the capsule (1) and subcapsular (or marginal) sinus (2) filled with lymphocytes. Left (A): (3) show perpendicularly localized reticular cells and fibres (blue) in the sinus. (4) indicate afferent lymph vessel with valves ... | lymph vessel; subcapsular sinus; follicle; cortex | Poja Histology Collection - Lymphatic Tissues and Organs Subset |
| 516 |
 |
Age involution of thymus (human) | Stain: Azan. A: Although the adipose tissue in the thymus of a patient of 65 years is predominant it still contains areas of remnants (arrows 1+2) of cortical (2) and medullary portions (1) of the thymus. B+C: Degradation of thymic tissues is less progressed in adults and shows less replacement of... | thymus age; thymus involution; adipose cells; lymphoid tissue | Poja Histology Collection - Lymphatic Tissues and Organs Subset |
| 517 |
 |
Age involution of thymus (human, postpuberal) | Stain: Azan. The size of the thymus is age-dependent, and undergoes a continuous process of involution, starting at postpuberal age. Due to depletion and reduced production of cortical thymocytes, as well as a gradual atrophy of the epithelial cells, the clear distinction between medulla (1) and cor... | thymus age; adipose cells; thymus involution; lymphoid tissue | Poja Histology Collection - Lymphatic Tissues and Organs Subset |
| 518 |
 |
Appendix ('gut-associated lymphatic tissue' or GALT) (human) | A large nodule in the appendix extends through the proper lamina (1) and submucosa. The nodule is similar to that found in a lymph node with germinal centre (2) and darker-stained cap (crescent) (3) orientated towards the lumen of the gut showing a flattened dome area covered with discontinuous epit... | GALT; follicle; lymphoid tissue | Poja Histology Collection - Lymphatic Tissues and Organs Subset |
| 519 |
 |
Appendix ('gut-associated lymphatic tissue' or GALT) (human) | Stain: Azan. Survey of vermiform appendix (see also Digestive System: Appendix) A large amount of non-encapsulated diffuse lymphatic tissue or mucosa-associated lymphatic tissue (MALT) is located in the subepithelial lamina propria/submucosa of the appendix and called gut-associated lymphatic tissue... | GALT; follicle; lymphoid tissue | Poja Histology Collection - Lymphatic Tissues and Organs Subset |
| 520 |
 |
Border of a marginal zone in spleen (rat) | Stain: Immunoelectron microscopy (gold labeling of heparan sulfate in Lowicryl embedding, using the single chain antibody HS4C3). The zone of red pulp immediately surrounding a lymphatic nodule is called the marginal zone (perilymphoid zone) and is composed of a scaffold of basal lamina material w... | marginal zone; immuno electron microscopy; heparan sulfate; dendritic cell | Poja Histology Collection - Lymphatic Tissues and Organs Subset |
| 521 |
 |
Border of white pulp in spleen (mouse) | Monoaminooxidase (enzyme histochemistry on frozen section) with Nitro-BT as staining substrate resulting in a blue formazan precipitate. Despite the general activity of most cells in the spleen, the border cells or so-called metallophilic cells (1) or dendritic antigen-presenting cells (APC) show th... | monoamino oxidase; ED3 antibody; follicle; white pulp | Poja Histology Collection - Lymphatic Tissues and Organs Subset |
| 522 |
 |
Calcified bacterial plaque in palatine tonsil ('gut-associated lymphatic tissue' or GALT) (human) | Stain: Azan. A tonsillar crypt lined by squamous epithelium (2) that is infiltrated with lymphocytes (1). It is a normal finding that within the crypts free cells, plugs of lymphocytes (1) and calcified epithelial debris as well as colonies of oral commensally bacteria are present. (3) shows a calc... | bacterial plaque | Poja Histology Collection - Lymphatic Tissues and Organs Subset |
| 523 |
 |
Circumscript reticular pattern of splenic lymphatic nodule (human) | Stain: Silver stain (Gomori). In this particular case the black-stained reticular network is beautiful organized in and around the nodule. Note also the reticulin staining between the myocytes in the wall of both cross-sectioned (1) central arteries. (2) follicle with lymphocytes. | sinusoid; reticular fibers; follicle | Poja Histology Collection - Lymphatic Tissues and Organs Subset |
| 524 |
 |
Colon ('gut-associated lymphatic tissue' or GALT) (human) | Stain: Hematoxylin-PAS. Solitary lymphatic nodule in colon (see also Digestive System: Colon) A large amount of non-encapsulated diffuse lymphatic tissue or mucosa-associated lymphatic tissue (MALT) is located in the subepithelial lamina propria of the colon and called gut-associated lymphatic tiss... | GALT; follicle; lymphoid tissue | Poja Histology Collection - Lymphatic Tissues and Organs Subset |
| 525 |
 |
Corpuscles in thymus (human, puberty) | Stain: Hematoxylin. A: Several thymic (Hassall's) corpuscles (*) of varying sizes within the medulla (1). The Hassall bodies are surrounded by recognizable flattened cells showing keratohyalin granules. The outer shell consists of more layers of close packed concentrically arranged cells with light-... | thymic corpuscle (Hassalls); epithelioreticular cell (ERC); thymus medulla; lymphoid tissue | Poja Histology Collection - Lymphatic Tissues and Organs Subset |