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TitleCreatorDescription
26 Paraneoplastic Diseases of Neuro-Ophthalmologic InterestJacobsen, Daniel M; Pomeranz, Howard D"A number of disorders characterized by visual dysfunction, neurologic dysfunction, or both occur in the setting of known or suspected cancers but do not result from the direct effects of the tumor."
27 PhacomatosesJohn Kerrison, MD, Retina Consultants of Charleston"Syndromes characterized by hamartomas of the skin, eye, central nervous system (CNS), and other viscera are collectivelycalled phacomatoses (1). These disorders produce significant visual and neurologic disturbances. Although most of these syndromes arise from mutations in single genes inherited in...
28 Topical Diagnosis of Chiasmal and Retrochiasmal DisordersLeonard A. Levin, MD, PhD. Chair of Ophthalmology, McGill University"The optic chiasm is one of the most important structures in neuro-ophthalmologic diagnosis. The arrangement of visual fibers in the chiasm accounts for the characteristic visual field defects caused by such diverse lesions as tumor, inflammation, demyelination, ischemia, and infiltration."
29 Bacteria and Bacterial DiseasesPrem S Subramanian, MD, PhD, ​Professor of Ophthalmology, Neurology, and Neurosurgery, University of ColoradoThis chapter describes various bacteria and bacterial diseases.
30 Nystagmus and Related Ocular Motility DisordersJohn R. Leigh, MD, Professor of Neurology, Emeritus, Case Western Reserve University; Rucker, Janet C"This chapter concerns abnormal eye movements that disrupt steady fixation and thereby degrade vision."
31 Peripheral Demyelinating and Axonal DisordersDavid I. Kaufman, DO, Chair, Neurology & Ophthalmology, Michigan State University"Guillain-Barre´ syndrome (GBS) until recently had been viewed as a single disorder with variations. It is now clear from electrophysiologic, pathologic, and immunologic evidence that it actually is a group of different syndromes with several distinctive subtypes (1)."
32 Prions and Prion DiseasesEric R. Eggenberger, DO, Mayo Clinic"The prion (pronounced ‘‘pree-on'') diseases are clinically heterogeneous, progressive neurodegenerative disorders that share similar pathologic features, primarily spongiform degeneration of the brain (Figs. 53.1 and 53.2) and are caused by a transmissible agent with biologic properties unlike ...
33 Retroviruses and Retroviral DiseasesLynn K. Gordon, MD, UCLA"The retroviridae family encompasses a group of viruses in which the replicative life cycle requires reverse transcription of the viral ribonucleic acid (RNA) genome into doublestranded deoxyribonucleic acid (DNA) (1)."
34 SarcoidosisSteven R. Hamilton, MD"Sarcoidosis is a systemic disorder of unknown etiology that has significant ocular, neurologic, and neuro-ophthalmologic manifestations."
35 Topical Diagnosis of TumorsNancy J. Newman, MD, Emory Eye Center"In this chapter, we consider the symptoms and signs that may occur in patients with ocular, orbital, intracranial, and spinal cord tumors."
36 The Trigeminal Nerve and Its Central ConnectionsGrant T. Liu, MD. Professor of Neurology, University of Pennsylvania"Because the three divisions of the trigeminal nerve run in close proximity to cranial nerves II, III, IV, and VI, sensory dysfunction in the face may be a symptom in neuro-ophthalmic patients with vision loss and eye movement disorders."
37 Viruses (Except Retroviruses) and Viral Diseases - Part 2Paul W. Brazis, MD, Mayo Clinic; Neil R Miller, M.D., Professor of Ophthalmology, Johns Hopkins University"Viruses are important causes not only of human systemic disease but also of neurologic and visual disease. It is not the purpose of this chapter to consider all known viruses that produce human disease or to consider all diseases produced by those viruses. Instead, we will restrict this chapter to ...
38 Mycoplasmal DiseasesBhatti, M Tarik"Mollicutes (trivial name, mycoplasmas) are the smallest free-living, replicating organisms known to humans, measuring 150 to 250 nm in diameter with a genome size ranging from 577 kilobase pairs (kbp) to 2200 kbp (compared with Escherichia coli, which has a diameter of 1000 nm and a genome size of ...
39 Compressive and Infiltrative Optic NeuropathiesNicholas J Volpe, MD, Northwestern University"Compressive lesions within the orbit, the optic canal and, rarely, intracranially, may result in disc swelling (Fig. 8.1)."
40 Degenerative and Metabolic Diseases in AdultsParashkev Nachev, PhD, MRCP(UK), University College London; Christopher Kennard, PhD, FRCP, FMed Sci, University of OxfordThis chapter describes degenerative and metabolic diseases in adults.
41 Disorders of Pupillary Function, Accommodation, and LacrimationAki Kawasaki, MD, PhD, Faculty of Biology and Medicine, University of Lausanne"In this chapter I describe various disorders that produce dysfunction of the autonomic nervous system as it pertains to the eye and orbit, including congenital and acquired disorders of pupillary function, accommodation, and lacrimation."
42 Multiple Sclerosis and Related Demyelinating DiseasesLaura J. Balcer, MD, Professor, Department of Neurology, NYU Langone"Destruction of myelin, demyelination, may occur in a variety of diverse inflammatory disorders. Demyelination may result from viral infections and is a prominent feature in the group of disorders known as the demyelinating diseases, of which multiple sclerosis (MS) is perhaps the most well known."
43 Normal and Abnormal Eyelid FunctionBarry Skarf, MD, PhD, Henry Ford Health System"Disorders of neuro-ophthalmologic significance may affect not only visual sensory, ocular motor, and pupil function but also the function of the eyelids."
44 Principles and Techniques of the Examination of the Visual Sensory SystemMichael Wall, MD, University of Iowa, Department of Neurology and Ophthalmology; Johnson, Chris A"This chapter describes the most common subjective and objective tests used in the afferent visual system examination."
45 Spirochetal DiseasesLesser, Robert L"Spirochetes are widely distributed in nature and often are found in aquatic environments, but they colonize humans. All spirochetal infections are characterized by skin or mucous membrane penetration followed by a spirochetemia that produces damage during several clinical stages (2)."
46 Supranuclear and Internuclear Ocular Motility DisordersZee, David S; Newman-Toker David"In this chapter, we survey clinicopathologic correlations for supranuclear ocular motor disorders."
47 Viruses (Except Retroviruses) and Viral Diseases - Part 1Paul W. Brazis, MD, Mayo Clinic; Neil R Miller, M.D., Professor of Ophthalmology, Johns Hopkins University"Viruses are important causes not only of human systemic disease but also of neurologic and visual disease. It is not the purpose of this chapter to consider all known viruses that produce human disease or to consider all diseases produced by those viruses. Instead, we will restrict this chapter to ...
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