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TitleCreatorDescription
26 Miscellaneous Tumors of Neuro-Ophthalmologic InterestBenjamin M. Frishberg, M.D."In this chapter we consider several tumors that may produce neuro-ophthalmologic symptoms and signs that do not specifically arise from intradural neural tissue."
27 Multiple Sclerosis and Related Demyelinating DiseasesLaura J. Balcer, MD, Professor, Department of Neurology, NYU Langone"Destruction of myelin, demyelination, may occur in a variety of diverse inflammatory disorders. Demyelination may result from viral infections and is a prominent feature in the group of disorders known as the demyelinating diseases, of which multiple sclerosis (MS) is perhaps the most well known."
28 Mycoplasmal DiseasesBhatti, M Tarik"Mollicutes (trivial name, mycoplasmas) are the smallest free-living, replicating organisms known to humans, measuring 150 to 250 nm in diameter with a genome size ranging from 577 kilobase pairs (kbp) to 2200 kbp (compared with Escherichia coli, which has a diameter of 1000 nm and a genome size of ...
29 Myopathies Affecting the Extraocular MusclesPaul N. Hoffman, MD, Departments of Neurology and Ophthalmology, Johns Hopkins Medicine"In this chapter, we consider disorders that produce ocular motor dysfunction from involvement of the extraocular muscles."
30 Neuro-Ophthalmologic Manifestations of Nonorganic DiseaseNeil R Miller, M.D., Professor of Ophthalmology, Johns Hopkins University"Patients who have physical signs and symptoms for which no adequate organic cause can be found may receive any one of a large range of diagnostic labels, including functional illness, functional overlay, hysteria, hysterical overlay, conversion reaction, psychophysiological reaction, somatization r...
31 Normal and Abnormal Eyelid FunctionBarry Skarf, MD, PhD, Henry Ford Health System"Disorders of neuro-ophthalmologic significance may affect not only visual sensory, ocular motor, and pupil function but also the function of the eyelids."
32 Nuclear and Infranuclear Ocular Motility DisordersJane C. Sargent, MD, Neurology, Clinical Neurophysiology, University of Massachusetts"Lesions of the oculomotor, trochlear, and abducens nerves may be located anywhere from the ocular motor nuclei to the termination of the nerves in the extraocular muscles in the orbit."
33 Nystagmus and Related Ocular Motility DisordersJohn R. Leigh, MD, Professor of Neurology, Emeritus, Case Western Reserve University; Rucker, Janet C"This chapter concerns abnormal eye movements that disrupt steady fixation and thereby degrade vision."
34 Optic NeuritisCraig H. Smith MD, Swedish Medical Center-Cherry Hill"Optic neuritis is a term usedto refer to inflammation of the optic nerve."
35 PapilledemaDeborah I. Friedman, MD, MPH, Professor, Neurology & Neurotherapeutics, University of Texas Southwestern"Papilledema is one of the most alarming signs in clinical medicine. Papilledema specifically refers to swelling of the optic disc resulting from increased intracranial pressure (ICP)."
36 Paraneoplastic Diseases of Neuro-Ophthalmologic InterestJacobsen, Daniel M; Pomeranz, Howard D"A number of disorders characterized by visual dysfunction, neurologic dysfunction, or both occur in the setting of known or suspected cancers but do not result from the direct effects of the tumor."
37 Peripheral Demyelinating and Axonal DisordersDavid I. Kaufman, DO, Chair, Neurology & Ophthalmology, Michigan State University"Guillain-Barre´ syndrome (GBS) until recently had been viewed as a single disorder with variations. It is now clear from electrophysiologic, pathologic, and immunologic evidence that it actually is a group of different syndromes with several distinctive subtypes (1)."
38 PhacomatosesJohn Kerrison, MD, Retina Consultants of Charleston"Syndromes characterized by hamartomas of the skin, eye, central nervous system (CNS), and other viscera are collectivelycalled phacomatoses (1). These disorders produce significant visual and neurologic disturbances. Although most of these syndromes arise from mutations in single genes inherited in...
39 Principles and Techniques of Examination of the Pupils, Accomodation, and LacrimationKathleen B. Digre, MD, Professor of Neurology and Ophthalmology, Director of Neuro-Ophthalmology, John A. Moran Eye Center, University of Utah School of Medicine"As is the case with any assessment in neuro-ophthalmology, assessment of the pupils requires a meticulous history and a rigorous examination."
40 Principles and Techniques of the Examination of the Ocular Motility and AlignmentMark S. Borchert, MD, University of Southern California"In this chapter, we discuss normal and abnormal monocular and binocular eye movements as they pertain to the techniques used in the examina-tion of patients with disorders of ocular motility."
41 Principles and Techniques of the Examination of the Visual Sensory SystemMichael Wall, MD, University of Iowa, Department of Neurology and Ophthalmology; Johnson, Chris A"This chapter describes the most common subjective and objective tests used in the afferent visual system examination."
42 Prions and Prion DiseasesEric R. Eggenberger, DO, Mayo Clinic"The prion (pronounced ‘‘pree-on'') diseases are clinically heterogeneous, progressive neurodegenerative disorders that share similar pathologic features, primarily spongiform degeneration of the brain (Figs. 53.1 and 53.2) and are caused by a transmissible agent with biologic properties unlike ...
43 Protozoa and Protozoal DiseasesWayne T. Cornblath, MD, Clinical Professor, Ophthalmology and Visual Sciences, Professor, Department of Neurology, University of Michigan"Protozoa (from the Latin words proto, meaning ‘‘first,'' and zoon, meaning ‘‘animal'') are acellular or unicellular organisms that are found all over the world in moist soil, fresh water, and oceans."
44 Retroviruses and Retroviral DiseasesLynn K. Gordon, MD, UCLA"The retroviridae family encompasses a group of viruses in which the replicative life cycle requires reverse transcription of the viral ribonucleic acid (RNA) genome into doublestranded deoxyribonucleic acid (DNA) (1)."
45 Rickettsiae, Rickettsial-Like Organisms, and the Diseases They ProduceVaphiades, Michael S; Miller, Neil R"Since the last edition of this text was published, advances in molecular biology have resulted in the reclassification of many organisms. Nowhere is this more apparent than in the area of the rickettsiae."
46 SarcoidosisSteven R. Hamilton, MD"Sarcoidosis is a systemic disorder of unknown etiology that has significant ocular, neurologic, and neuro-ophthalmologic manifestations."
47 Secition 6: Nonorganic DiseaseNancy J. Newman, MD, Emory Eye CenterAn overview of Section 6.
48 Section 10: Degenerative and Metabolic DiseasesJohn Kerrison, MD, Retina Consultants of CharlestonAn overview of Section 10.
49 Section 11: Infectious, Inflammatory, and Demyelinating DiseasesNeil R Miller, M.D., Professor of Ophthalmology, Johns Hopkins UniversityAn overview of Section 11.
50 Section 1: The Visual Sensory SystemNancy J. Newman, MD, Emory Eye CenterAn overview of Section 1.
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