The NANOS Annual Meeting Neuro-Ophthalmology Collection: Presentations from the annual meeting of the North American Neuro-Ophthalmology Society (NANOS), a professional organization of more than 600 members who are fully trained ophthalmologists or neurologists. Contains records from the first meeting in 1975 to the present.
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| Title | Curriculum | Description | Subject | Collection | ||
|---|---|---|---|---|---|---|
| 1 |
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Visible Optic Disc Drusen in a Children | Optic disc drusen are acellular deposits located in the head of the optic nerve that increase in size and become calcified over time. Drusen tend to buried in early life and become superficial and visible later in childhood, at an average age of 10-12 years. We had the opportunity to evaluate a 5-ye... | Pediatric Neuro-ophthalmology; Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc); Miscellaneous | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 2 |
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Optic Disc Drusen: Insights on Diagnosis | Guidelines for enhanced-depth imaging have improved the diagnosis of optic disc drusen and attempt to address confusion within the literature. In particular the presence of peripapillary mass-like structures have caused this confusion and potentially lead to misclassification of some disc oedema. Th... | Optic Disc Drusen; Peripapillary Hyperreflective Ovoid Mass-like Structures; Optical Coherence Tomography; Ocular Ultrasound; Visual Field | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 3 |
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The Influence of Volume and Anatomic Location of Optic Disc Drusen on Sensitivity of Autofluorescence | Optic disc drusen are acellular deposits in the optic nerve head. Optic disc drusen can be diagnosed using different imaging modalities such as enhanced depth imaging optical coherence tomography and autofluorescence. It is unknown which factors determine the sensitivity of autofluorescence. The aim... | Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc) Eyelid & Adnexal Disease | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 4 |
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OCT and Optic Nerve Head Drusen (abstract) | Patient Care; Medical Knowledge; PBLI; VBnflaopticalcoherencetomography; KBDexposeddrusen; KBDburieddrusen; KBDlittlereddiscs; KBDcongenitalblurreddisc; IC-C6bvi-optic-disc-drusen | Optic nerve head drusen (ONHD) are deposits of calcium, amino and nucleic acids, and mucopolysaccharides, which may be buried within the optic nerve or lie at the surface of the optic disc.1 These deposits often become calcified over time. Clinically apparent ONHD are estimated to occur in 0.3% of t... | Spectral-Domain OCT, Superficial ONHD, Buried ONHD, Enhanced Depth Imaging OCT, Swept Source OCT, Papilledema, Pseudopapilledema | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
| 5 |
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In-Clinic Detection of Optic Disc Drusen Using Hand-Held Ultrasound Technology | Differentiation of pseudopapilledema from true papilledema is a common reason for referral to neuro-ophthalmology. Optic disc drusen is a frequent cause of pseudopapilledema, though buried drusen may not be visible on fundus examination. Ancillary testing including ultrasonography can rapidly identi... | Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc); Orbit/Ocular Pathology | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 6 |
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Optic Disc Drusen Visualization with Auto-Fluorescent Imaging | Minimally buried optic disc drusen may present as swelling of the optic disc. Drusen auto-fluoresce when excited by short wavelength light. To distinguish disc edema from buried disc drusen, auto-fluorescent imaging may be useful. | Optic Disc Drusen; Auto-Fluorescence; Scanning Laser Ophthalmoscope | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 7 |
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Concomitant Optic Disc Drusen and Papilledema Due to Idiopathic Intracranial Hypertension in a Pediatric Cohort | Recent studies have shown higher rates of optic disc drusen (ODD) among pediatric patients with idiopathic intracranial hypertension (IIH). In this study, we retrospectively reviewed the patients with confirmed ODD to evaluate the rate and characteristics of concomitant IIH. | Pediatric Neuro-ophthalmology; Pseudotumor Cerebri | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 8 |
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Measurement of Scleral Canal Area Using Optical Coherence Tomography in Patients with Optic Nerve Drusen | The pathophysiology of optic nerve drusen (OND) is speculative. It has been proposed that optic nerve drusen are formed when retinal ganglion cell axons die and extrude their mitochondria (Tso, 1981). These extruded mitochondria serve as nidifor calcification. However, it is not clear why these gang... | optic nerve drusen; optical coherence tomography; scleral canal | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 9 |
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Scanning Laser Polarimetry for the Detection of Nerve Fiber Layer Defects in Patients with Optic Nerve Drusen | Patients with optic nerve drusen may have other diseases of the optic nerve, including glaucoma, complicating the evaluation of visual field defects. In diseases of the optic nerve, visual field defects result from loss of ganglion cells and thinning of the retinal nerve fiber layer. We performed sc... | Optic Nerve Drusen; Visual Field Defects; Nerve Fiber Layer Defects; Laser Polarimetry | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 10 |
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Novel Cellular and Animal Models of Optic Disc Drusen | Optic disc drusen (ODD) are calcified deposits of the anterior optic nerve and result in visual field loss in majority of patients.1 Most common cause of vision loss is anterior ischemic optic neuropathy (AION). Ultrastructurally, the hallmark of ODD is mitochondrial calcification,2 and energy dispe... | Optic Neuropathy; Genetic Disease | Neuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 11 |
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Real or Fake? We Can All Make a Mistake | The task of accurately identifying papilledema and distinguishing it from pseudopapilledema can be especially challenging in children. Two clinical cases are presented to highlight how subtle this distinction can be and the difficulty in correctly diagnosing underlying pathology and treating it prom... | Intracranial Hypertension; Papilledema; Craniosynostosis; Pseudopapilledema; Optic Disc Drusen | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 12 |
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Peripapillary Retinal Nerve Fiber Layer Thickness Corresponds To Drusen Location And Extent Of Visual Field Defects In Patients With Optic Disc Drusen | "Optic disc drusen (ODD) are hyaline deposits located within the optic nerve head. While a minority of ODD patients are affected by complications such as anterior ischemic optic neuropathy and retinal hemorrhages, optic coherence tomography (OCT) reveals thinning of the peripapillary retinal nerve f... | Optic Disc Drusen, Retinal Nerve Fiber Layer, Visual Fields, Perimetry | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 13 |
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Long-term OCT Follow-up in Children with Optic Disc Drusen | A better understanding of optic disc drusen (ODD) etiology and pathophysiology might be possible by visualizing progression of ODD and potential precurser lesions. The purpose of this study was to examine the progression of ODD and scleral canal diameter in children previously diagnosed with ODD and... | Optic Neuropathy, Pediatric Neuro-Ophthalmology | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 14 |
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Enhanced Depth Imaging Optical Coherence Tomography in Diagnosis of Disc Drusen in a Pediatric Cohort | Optic disc drusen (ODD) can present a confounding clinical picture because they are often difficult to differentiate from disc edema. As OCT technology has evolved, enhanced depth imaging EDI-OCT has become a valuable tool for diagnosing ODD. In spite of this, no consensus regarding diagnostic crite... | Pediatric neuro-ophthalmology | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 15 |
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The Visual Morbidity of Optic Nerve Head Drusen in Children: A Longitudinal Review | The ophthalmic complications of optic nerve head drusen (ONHD) in adults have long been documented, but data regarding the degree of visual morbidity from ONHD in children are more limited. We sought to characterize the extent of vision loss and secondary complications associated with ONHD in a larg... | Optic Neuropathy; Visual Fields | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 16 |
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Real or Fake? We Can All Make a Mistake | The task of accurately identifying papilledema and distinguishing it from pseudopapilledema can be especially challenging in children. Two clinical cases are presented to highlight how subtle this distinction can be and the difficulty in correctly diagnosing underlying pathology and treating it prom... | Intracranial Hypertension; Papilledema; Craniosynostosis; Pseudopapilledema; Optic Disc Drusen | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 17 |
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The Characteristics Of Optic Nerve Head Drusen on Optical Coherence Topography (OCT) | Our objective was to describe the characteristics of optic nerve head drusen in images obtained by OCT. | Optic Nerve Head Drusen; Optical Coherence Tomography; Spectral OCT; Papilledema | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 18 |
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Mining for ODD Using Multimodal OCT | Optic disc drusen (ODD) are acellular, calcified deposits localized between the axons in the prelaminar optic nerve head of about 2% of the population. | Optic Disc Drusen; Optical Coherence Tomography; Enhanced Depth Imaging; Swept Source; Detection | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 19 |
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Longitudinal Study of Structure and Function in Optic Disc Drusen | Optic disc drusen are associated with vision loss, either as anterior ischemic optic neuropathy or glaucoma.[1] We ask whether patients with no overt vision loss exhibit structural worsening over years. | Optic Neuropathy; Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc); Perimetry; Visual Fields | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 20 |
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Novel Cellular and Animal Models of Optic Disc Drusen | Optic disc drusen (ODD) are calcified deposits of the anterior optic nerve and result in visual field loss in majority of patients.1 Most common cause of vision loss is anterior ischemic optic neuropathy (AION). Ultrastructurally, the hallmark of ODD is mitochondrial calcification,2 and energy dispe... | Optic Neuropathy; Genetic Disease | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 21 |
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Optic Disc Drusen: Insights on Diagnosis | Guidelines for enhanced-depth imaging have improved the diagnosis of optic disc drusen and attempt to address confusion within the literature. In particular the presence of peripapillary mass-like structures have caused this confusion and potentially lead to misclassification of some disc oedema. Th... | Optic Disc Drusen; Peripapillary Hyperreflective Ovoid Mass-like Structures; Optical Coherence Tomography; Ocular Ultrasound; Visual Field | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 22 |
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Anterior Ischemic Optic Neuropathy in Eyes with Optic Disc Drusen | There have been anecdotal reports of anterior ischemic optic neuropathy (AION) occurring in eyes with optic disc drusen (ODD) but the clinical features of this condition have not been well characterized. | anterior ischemic optic neuropathy; optic disc drusen; congenital disc anomaly | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 23 |
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Diagnostic Uncertainty Due to Optic Disc Drusen | Optic disc drusen (ODD) are a frequent cause of optic disc elevation raising the possibility of optic disc edema. Papillary and peripapillary hemorrhages with or without optic disc edema may occur with ODD further confounding the clinical picture. | Optic disc drusen; Papilledema; NAION; Peripapillary hemorrhages; Choroidal neovascularization | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 24 |
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Fluorescein Angiographic Identification of Optic Disc Edema in Patients with Optic Disc Drusen | The differentiation of optic disc drusen (ODD) from true optic disc edema (ODE) may be difficult, and ancillary testing may be inconclusive, particularly when ODD and ODE coexist. | Optic disk drusen; Optic nerve edema; Fluorescein angiography | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu | |
| 25 |
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The Genetics of Optic Nerve Drusen | Lorentzen was the first investigator to propose an autosomal dominant inheritence pattern for optic nerve drusen. He found that the prevalence of drusen among first-degree relatives was 7.8%, significantly higher than that observed in the general population (2.04%). Lorentzen's observations were bas... | Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |