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Title | Creator | History |
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Acute Homonymous Quadrantanopia and Patent Foramen Ovale | Mark J. Kupersmith, MD; Daniel R. Lefton, MD | A 27-year old female with 1-day history of dark gray visual disturbance in the right visual field interfering with reading. |
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A Progressive Neurological Disorder with Ring Enhancing CT Lesion | James A. Garrity, MD; James C. Trautmann, MD; Brian R. Younge, MD | A 69-year old female with difficulty coordinating colors, reading, writing and with fine motor movements. |
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Homonymous Hemianopia in a Young Woman | Deborah I. Friedman, MD | A 21-year old female with a right homonymous hemianopia. |
4 |
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Oh, You Have Metastatic Cancer | Elena Sokolova; John Carter; Damon Herbert | A 59-year old male who noted when driving the cars approaching would disappear and reappears further to the side in his peripheral vision. |
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Oh, You Have Metastatic Cancer' (PowerPoint) | Elena Sokolova; John Carter; Damon Herbert | A 59-year old male noted when driving the cars approaching disappear and reappears further to the side in his peripheral vision. |
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Oh, You Have Metastatic Cancer' (Presentation Video) | Elena Sokolova; John Carter; Damon Herbert | A 59-year old male noted when driving the cars approaching disappear and reappears further to the side in his peripheral vision. |
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Chiasmal Conundrum | Richard E. Appen, MD | A 41-year old male with progressive, painless blurred vision OD of a 3-week duration and for ten days OS. Previous history significant for chorioretinitis. |
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Optico-Ghiashatic Arachnoiditis in Multiple Sclerosis | D. M. Robertson, MD; D. A. Rosen, MD; R. Bell, MD; A. Kerr, MD | A 45-year old male with an 11-year history of blurred vision OS. |
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Retinal Venous Sheathing in Multiple Sclerosis | Anthony C. Arnold, MD; Robert S. Hepler, MD; Robert Y. Foos, MD | Case 1: A 24 year old female with horizontal diplopia, upper extremity incoordination and right lower extremity weakness. Case 2: A 53-year old male with a 5-year history of episodic numbness and paresthesias of both lower extremities. |
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In Vivo Antibody Mediated Optic Nerve Demyelination | Robert C. Sergott, MD; Mark J. Brown, MD; Donald H. Silberberg, MD | Demyelination of the central nervous system (CNS) without coincident axonal damage is a characteristic pathologic lesion in multiple sclerosis (MS) and in optic neuritis, one of the frequent findings in MS. |
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Rapidly Shifting into Third Gear | Dina Jacobs, MD; Steven Galetta, MD; Clyde Markowitz, MD; Robert Shin, MD; Alex Judkins, MD; Peter Nelson, MD, PhD | A 67-year old woman developed onset of visual loss in her left eye, 2 days after the resection of two basal cell carcinomas from her nose. |
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A Mystery Case of Proptosis, Optic Neuropathy, and Peripheral Neuropathy | Bonnie Keung; Judith Warner; Kathleen Digre; Bradley Katz; Steven Chin; Lubdha Shah; Danielle Eckart | Age 7 - headaches and vision loss to count fingers in left eye; Age 13 - diagnosed with multiple sclerosis; Age 22 - diplopia thought to be bilateral INO; identical twin with sequential bilateral optic neuritis at 8 years, diagnosis of multiple sclerosis at 12 years, and repeated exacerbations of ga... |
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A Mystery Case of Proptosis, Optic Neuropathy, and Peripheral Neuropathy | Bonnie Keung; Judith Warner; Kathleen Digre; Bradley Katz; Steven Chin; Lubdha Shah; Danielle Eckart | Age 7 - headaches and vision loss to count fingers in left eye; Age 13 - diagnosed with multiple sclerosis; Age 22 - diplopia thought to be bilateral INO; identical twin with sequential bilateral optic neuritis at 8 years, diagnosis of multiple sclerosis at 12 years, and repeated exacerbations of ga... |
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An Unusual Case of Multiple Sclerosis | Neil R. Miller, MD; John Chambers, MD | A 39-year old female with horizontal gaze on lateral gaze. Previous history significant for progressive poor coordination and sequelae subsequently diagnosed as multiple sclerosis. |
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Progressive Neurologic Dysfunction and Optic Neuropathy | Nicholas J. Volpe, MD; Elizabeth Plotkin; Malcolm McHarg, MD; Laura J. Balcer, MD; Steven L. Galetta, MD | A 72-year old female with an acute onset of gait unsteadiness and leg weakness. |
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Tell-Tale Third | M. Tariq Bhatti, MD | A 30-year old female with a 1-day history of binocular diplopia associated with pain over the left eyebrow. |
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Orbital Pseudo Tumor Followed by MS | Jon N. Curry, MD; James R. Coppeto, MD; Simmons Lessell, MD | A 58-year old male with a 4-month history of progressive gait disturbance and dysphagia. Previous history significant for multiple sclerosis and orbital pseudotumor. |
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Get Me Out of Here; It's Too Crowded | Melissa Wang-Ko; Madhura Tamhankar; Nicholas Volpe; Steven Galetta; David Porter; Cindy McGrath | A 54-year old female with 6-week history of progressive deteriorating vision OU, headache and pain associated with eye movement. Previous history significant for multiple sclerosis. |
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Get Me Out of Here; It's Too Crowded (PowerPoint) | Melissa Wang-Ko; Madhura Tamhankar; Nicholas Volpe; Steven Galetta; David Porter; Cindy McGrath | A 54-year old female with a 6-week history of progressive deteriorating vision OU, headache and pain associating with eye movements. Previous history significant for multiple sclerosis. |
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Get Me Out of Here; It's Too Crowded (Presentation Video) | Melissa Wang-Ko; Madhura Tamhankar; Nicholas Volpe; Steven Galetta; David Porter; Cindy McGrath | A 54-year old female with 6-week history of progressive deteriorating vision OU, headache and pain associated with eye movement. Previous history significant for multiple sclerosis. |
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Biochemical Approach to Demyelination | E. K. Wong, MD; H. Enomoto, MD; R. Jones, MD; I. H. Leopold, MD | In 1980, our researchers in the Department of Ophthalmology, UC Irvine, were the first to describe abnormally low plasma zinc levels in patients with demyeli-nation. |
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A Biochemical Approach to Demyelination | E. K. Wong; H. Enomoto; R. Jones; I. H. Leopold | Multiple sclerosis is a disease that has baffled medical science. With no known cause, pathogenesis or therapies. Neuro-ophthalmogists are often the first physicians to evaluate and manage patients with they present with optic neuritis. |