The Alfredo A. Sadun Neuro-Ophthalmology Collection: A Professor of Ophthalmology and Neurological Surgery at the USC Keck School of Medicine, Dr. Sadun with a team of researchers at the Doheny Eye Institute pioneered research in optic nerve dysfunction in patients with Alzheimer's disease. Contains his "100 best lectures." Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor Ophthalmology & Neurological Surgery, Doheny Eye Institute, Keck School of Medicine at USC.
NOVEL: https://novel.utah.edu/
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Filters: Collection: "ehsl_novel_aas"
| Title | Description | Type | ||
|---|---|---|---|---|
| 1 |
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Posterior Ischemic Optic Neuropathy | Discusses opthalmic complications of surgery, with example of shock-induced Posterior Ischemic Optic Neuropathy following a hysterectomy. Presenting Symptom: Ischemia; Hypotension. Anatomy: Optic nerve. Disease/Diagnosis: Optic neuropathy, Ischemic; Hematoma; Edema. | Text |
| 2 |
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Atypical Optic Neuropathies | A discussion of atypical optic neuropathies. Anatomy: Optic nerve; Optic disc. Pathology: Slides showing LHON. Disease/Diagnosis: Optic neuropathy, Ischemic; Optic atrophy, Hereditary, Leber; Toxic optic neuropathy. Presenting Symptom: Optic neuritis; Eye hemorrhage; Retinal vasculitis; Dyschromatop... | Text |
| 3 |
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Acute Retrobulbar Optical Neuropathy | PPT covering acute retrobulbar optic neuropathy, including ischemic, inflammatory, anterior ischemic optic neuropathy (AION) and non-arteritic anterior ischemic optic neuropathy (NAION); includes brainscan images for optic neuritis and multiple sclerosis; optic disk with LHON and PION. Anatomy: Opt... | Text |
| 4 |
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How Strong is the Case for an Association Between PDE5 Inhibitors and NAION? | Anatomy: Optic nerve. Disease/Diagnosis: Optic Neuropathy, Ischemic; Toxic optic neuropathy. Presenting Symptom: Ischemia; Scotoma; Dyschromatopsia. | Text |
| 5 |
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Viagra and Vision Loss: Does Sex Make You Blind? | At a formal debate during a meeting in Canada in Sept. 2006, Sadun was assigned the role of arguing the case FOR a connection between taking phosphodiesterase 5 (PDE5) inhibitors and developing anterior ischemic optic neuropathy. Presenting Symptom: Hypotension. Anatomy: Optic nerve; Optic disc; Cyc... | Text |
| 6 |
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Viagra and Vision Loss: Does Sex Make You Blind? | Presenting symptom: Hypotension. Anatomy: Optic nerve; Optic disc; Cyclic Nucleotide Phosphodiesterases, Type 5. Disease/Diagnosis: Optic Neuropathy, Ischemic; Toxic optic neuropathy. | Text |
| 7 |
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The Diagnostic Workup in Patients With Optic Neuropathies (Metodo diagnostico) | Slideshow presentation with images of optic disc with edema and "Positive temporal artery biopsy". Presenting Symptom: Hyperopia; Metamorphopsia. Anatomy: Optic nerve; Macula Lutea; Optic disc. Disease/Diagnosis: Optic neuritis; Macular edema; Optic neuropathy, Ischemic. | Text |
| 8 |
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The Diagnostic Workup in Patients With Optic Neuropathies | Slideshow presentation with images of optic disc with edema and optic atrophy. Presenting Symptom: Telangiectasis; Dyschromatopsia; Scotoma. Anatomy: Optic nerve; Optic disc; Phosphopyruvate Hydratase; Enolase. Disease/Diagnosis: Optic neuritis; Macular edema; Optic neuropathy, Ischemic; Optic atrop... | Text |
| 9 |
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Optic Nerve Sheath Decompression in the Management of Optic Neuropathies | A slide presentation with several images of optic disc, normal and with edema. Anatomy: Optic nerve; Optic disc. Disease/Diagnosis: Optic neuropathy, Ischemic; Pseudotumor cerebri; Papilledema. Treatment: Decompression, Surgical. | Text |
| 10 |
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The Clinical Spectrum of Amiodarone-Associated Optic Neuropathy | Sadun's response to a paper by L.N. Johnson, G.B. Kroheld, and E.R. Thomas at 2004 AAO meeting. Anatomy: Optic nerve. Disease/Diagnosis: Optic nerve diseases; Optic neuropathy, Ischemic | Text |
| 11 |
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Toxic Optic Neuropathies: Mitochondria and the RGC | Discussion of various forms of mitrochondrial optic neuropathies and how to distinguish from toxic optic neuropathies, with examples from Cuba and Brazil; includes images of optic disc showing LHON. Presenting Symptom: Blindness; Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia. Anatomy: Optic ne... | Text |
| 12 |
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Mitochondrial Optic Neuropathies (MON) | Combination of two presentations on optic nerve diseases, covering the cases in Cuba and Brazil. Titles: Cuban epidemic of optic neuopathy: even zealots must eat, or, Conversations with Castro and Leber's hereditary optic neuropathy: a very large new pedigree in Brazil; includes several images of ... | Text |
| 13 |
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Mitochondrial Optic Neuropathy: Mitochondria as Gatekeepers for Apoptosis | Anatomy: Optic nerve; Retina; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber; Toxic optic neuropathy. Presenting Symptom: Scotoma; Dyschromatopsia. | Text |
| 14 |
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Mitochondria and the RGC | Discussion of various forms of mitrochondrial optic neuropathies and how to distinguish from toxic optic neuropathies, with examples from Cuba and Brazil. Presenting Symptom: Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia. Anatomy: Optic nerve; Optic disc; Retinal ganglion cells; Reactive oxyge... | Text |
| 15 |
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Mitochondrial Optic Neuropathy: Mitochondria as Gatekeepers for Apoptosis | Presentation at Harvard in 2006, focussing on Leber's Heriditary Optic Neuropathy; includes several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells. Disease/Diagnosis: Optic nerve diseases; Optic Atrophy, Hereditary, Leber. Presenting Symptom:... | Text |
| 16 |
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The Neuro-Ophthalmic Manifestations of Diabetes | Anatomy: Orbit; Optic nerve. Disease/Diagnosis: Diabetes; Mucormycosis; Acidosis; Hypoplasia of the optic nerve; Diabetes mellitus; Diabetic optic papillopathy; Optic neuropathy, Ischemic; Diabetic optic atrophy; Ophthalmoplegia; Arteritis; Diabetic ketoacidosis; Orbital cellulitis. Treatment: Debri... | Text |
| 17 |
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Pupils and the Neuro-Ophthalmic Manifestations of Diabetes | Presentation given in Italy on diagnosing neuro-opthalmic complications of diabetes with several views of the optic disc. Presenting symptom: Diplopia; Anisocoria; Ptosis; Horner syndrome; Adie syndrome. Anatomy: Pupil; Optic disc; Optic nerve. Disease/Diagnosis: Diabetes; Mucormycosis; Acidosis; Hy... | Text |
| 18 |
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Cuban Epidemic of Optic Neuropathy: Even Zealots Must Eat, or, Conversations with Castro | A team of neuro-opthalmologists visits Cuba in 1993 and 1994, and attempts to treat patients with vision disorders. Anatomy: Optic nerve. Disease/Diagnosis: Optic nerve diseases; Alcoholic neuropathy. Treatment: Folate. Presenting Symptom: Blindness; Ambliopia; Ataxia; Paresthesia; Hyporeflexia. | Text |
| 19 |
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Distinguishing an Optic Neuropathy from a Maculopathy | PPT describing a case of optic neuropathy. Covers signs and symptoms, and various laboratory tests. Describes 10 signes of disc edema. Anatomy: Optic nerve; Retina; Retinal macula. Disease/Diagnosis: Optic nerve diseases; Retinal lesion; Macular lesion; Disorder of the optic nerve; Afferent pupillar... | Text |
| 20 |
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Toxic Optic Neuropathies: How Much Evidence Should it Take to Convict? | A critique of claims that the drug Amiodarone causes optic neuropathies. Presenting Symptom: Scotoma; Dyschromatopsia. Anatomy: Optic nerve. Disease/Diagnosis: Toxic optic neuropathy. | Text |
| 21 |
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Leber's Hereditary Optic Neuropathy: A Very Large New Pedigree From Brazil | Four slides showing optic disc with LHON. Anatomy: Optic nerve; Optic disk. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Blindness. | Text |
| 22 |
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Cuban Epidemic of Optic Neuropathy: Even Zealots Must Eat, or, Conversations with Castro | A team of neuro-opthalmologists visits Cuba in 1993 and 1994, and attempts to treat patients with vision disorders. Anatomy: Optic nerve; Structure of cribriform plate. Disease/Diagnosis: Optic nerve diseases; Blindness; Ambliopia; Alcoholic neuropathy. Treatment: Folate. Presenting Symptom: Ataxia;... | Text |
| 23 |
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Leber's Hereditary Optic Neuropathy: A Very Large New Pedigree in Brazil | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis. Includes several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Optic disk. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Blindnes... | Text |
| 24 |
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How Mitochondria Orchestrate the Death of RGCs : From Brazil to Tuebingen to Rochester 2007 | Slides showing LHON and Kjer's optic atrophy and images of optic disk with LHON. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia; Blindness. | Text |
| 25 |
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An Epidemic of Blindness in Cuba: Lessons on Nutrition and Mitochondria | Presented at Stanford in April 2007, recapping the 1990s expedition to Cuba to investigate causes of blindness epidemic. Anatomy: Optic nerve. Disease/Diagnosis: Optic nerve diseases; Alcoholic neuropathy. Treatment: Folate. Presenting Symptom: Ambliopia; Ataxia; Paresthesia; Hyporeflexia. | Text |