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TitleDescriptionSubjectCollection
1 (Pro)myelocyte and neutrophilic granulocytes in bone marrow smear (human)Stain: May-Grnwald-Giemsa (MGG). The promyelocyte (1) contains coarse primary, azurophilic granules in the basophilic cytoplasm. The absence of nucleoli indicates the late stage of the promyelocyte. (2) segmented neutrophilic granulocyte with toxic granulation (large irregular granules). (3) indicat...Poja Histology Collection - Blood & Bone Marrow Subset
2 1.0 Biosynthesis of Steroid Hormones - IntroductionA video introduction to the biosynthesis of steroid hormones. Guide questions -- What types of compounds are included in the class of steroids? Why is it important to know the sources and pathways in the synthesis of steroid hormones? University of Cincinnati College of Medicine Reproductive Phys...Biosynthesis; Hormone Deficiency; Steroid Hormones; Excess; PathwaysHEAL Reviewed Collection
3 2.0 Sexual Differentiation and Development - IntroductionIntroduction to disorders of sexual differentiation and development. University of Cincinnati College of Medicine Reproductive Physiology Modules: Part 2.0. Requires the Macromedia Flash Player plug-in. A Blackboard course complete with goals, guide questions and quizzes is the framework for these m...Steroid Hormones; Hormone Deficiency; Genetic SexHEAL Reviewed Collection
4 3.0 Neuroendocrine Control of Reproduction and Puberty - IntroductionIntroduction to the neuroendocrine control of reproduction and puberty. University of Cincinnati College of Medicine Reproductive Physiology Modules: Part 3.0. Requires the Macromedia Flash Player plug-in. A Blackboard course complete with goals, guide questions and quizzes is the framework for thes...Steroid Hormones; Reproductive CyclicityHEAL Reviewed Collection
5 A bare megakaryocyte nucleus and myelocytes in bone marrow smear (human)Stain: May-Grnwald-Giemsa (MGG). (1) Indicates a bare large-sized polyploid nucleus of a megakaryocyte which has totally shed the cytoplasm. These cells are often seen in normal marrow and are ultimately removed by macrophages. There is no cytoplasm left, nor platelets are left around the nucleus. T...Poja Histology Collection - Blood & Bone Marrow Subset
6 A bare megakaryocyte nucleus in bone marrow smear (human)Stain: May-Grnwald-Giemsa (MGG). (1) indicates a naked, large-sized polyploid nucleus of a megakaryocyte with visible lobes. No cytoplasm nor platelets are left around the nucleus. Most surrounding cells are of myeloid origin, except one orthochromatic erythroblast (2).Poja Histology Collection - Blood & Bone Marrow Subset
7 A plasmacytoid lymphocyte in peripheral blood smear (human)Stain: May-Grnwald-Giemsa (MGG). The plasmacytoid lymphocyte is an activated B lymphocyte to be transformed into a plasma cell. The cytoplasm is more basophilic and the chromatin pattern is more clumped than in a virgin small lymphocyte. When the cell contains numerous immunoglobulin inclusions (glo...Poja Histology Collection - Blood & Bone Marrow Subset
8 Activated lymphocyte (liver inflammation, human)Electron microscopy. A cytotoxic T cell (2) is localized within the sinusoid (3) in the liver (8), surrounded by erythrocytes (1) and debris. The lymphocyte with an irregular indented nucleus shows juxta-nuclearly partly swollen Golgi areas (*) and aggregation of mitochondria (4) in the cytoplasm. F...Poja Histology Collection - Blood & Bone Marrow Subset
9 Adrenal gland with granulomatous reaction (gumma) to syphilisThis high power image (20X) shows a granuloma with a giant cell in the adrenal gland. The granuloma is a gumma formed during tertiary syphilisgummaHEAL Reviewed Collection
10 Adrenal gland with granulomatous reaction (gumma) to syphilisThis medium power image shows a granuloma in the adrenal gland. The granuloma is a gumma formed during tertiary syphilis.GummaHEAL Reviewed Collection
11 Aggregation of platelets (liver, rat)Electron microscopy. Within a liver sinusoid (S) close to a small bile ductile (B) in the periportal area of the liver some erythocytes (E) and an aggregation of platelets (3) are present. (2) represents the space of Disse to which the liver parenchyma cells border (1). These disc-shaped anucleate p...Poja Histology Collection - Blood & Bone Marrow Subset
12 Anemic bone marrow smear in iron deficiency (human)Stain: May-Grnwald-Giemsa (MGG). Due to iron deficiency the erythrocytes (1) look empty, while also the erythroblasts (2) are relatively small and show a ruffled cell border.Poja Histology Collection - Blood & Bone Marrow Subset
13 Anisocytosis of erythrocytes in peripheral blood smear (human)Stain: May-Grnwald-Giemsa (MGG). (A) shows normal human erythrocytes in a blood film, while (B) shows anisocytosis. The small cells are called microcytes. Anisocytosis is an increase in the variability of erythrocyte size beyond that which is observed in a normal healthy subject. It is a common, non...Poja Histology Collection - Blood & Bone Marrow Subset
14 Band and hyper segmented neutrophils in peripheral blood smear (human)Stain: May-Grnwald-Giemsa (MGG). (A) shows a young band neutrophil with a non-segmented nucleus. (B) shows mature neutrophils with more than 6 nuclear lobes (hyper segmented). The smear also shows anisocytosis with both microcytes and macrocytes.Poja Histology Collection - Blood & Bone Marrow Subset
15 Band form of neutrophilic granulocyteScheme electron microscopy. From CFU-S (colony forming units-spleen) stem cells arise CFU-GM (colony forming unit-granulocyte/monocyte) stem cells. The latter divide by mitoses and differentiate via promyeloblasts and myeloblasts into neutrophilic myelocytes (the last proliferative stage). The next ...Poja Histology Collection - Blood & Bone Marrow Subset
16 Band-form of neutrophilic granulocyte (peripheral blood, human)Electron microscopy. Transition from late metamyelocyte to band form (9-12 μm). These are the earliest stages of the motile two-lobed neutrophilic granulocytes. (1) a slightly bended nucleus with a nucleolus. (2) Golgi area. Apart from a few mitochondria (3) and profiles of rough endoplasmic retic...Poja Histology Collection - Blood & Bone Marrow Subset
17 Basophilic erythroblast and myeloid cells in bone marrow smear (human)Stain: May-Grnwald-Giemsa (MGG). (1) early basophilic erythroblast. (2) eosinophilic metamyelocyte. (3) neutrophilic myelocyte. (4) two band neutrophils.Poja Histology Collection - Blood & Bone Marrow Subset
18 Basophilic erythroblast and polychromatic erythroblasts in bone marrow smear (human)Stain: May-Grnwald-Giemsa (MGG). The basophilic erythroblast (1) shows slightly condensed chromatin and a strong basophilic (blue) cytoplasm. In the two polychromatic erythroblasts the chromatin condensation has progressed considerably, and the cytoplasm is much less basophilic. The cells are also s...Poja Histology Collection - Blood & Bone Marrow Subset
19 Basophilic erythroblast, plasmacytoid lymphocyte and neutrophilic granulocyte in bone marrow smear (human)Stain: May-Grnwald-Giemsa (MGG). The basophilic erythroblast (1) contains a large, partly condensed but transparent nucleus with a distinct nucleolus. The cytoplasm is strong basophilic. The plasmacytoid lymphocyte (2) or activated B cell is much smaller and less basophilic. The young neutrophil (3)...Poja Histology Collection - Blood & Bone Marrow Subset
20 Basophilic granulocyteScheme electron microscopy. Basophils are non-phagocytic granulocytes that account for 0.5% to 1.0% of the circulating white blood cells. Their granulated cytoplasm stains with basic dyes, hence the name basophil. Electron microscopy reveals a multilobed nucleus (1); few mitochondria (2); numerous ...Poja Histology Collection - Blood & Bone Marrow Subset
21 Basophilic granulocyte (peripheral blood, human)Electron microscopy. The bilobed nucleus (2) is surrounded by moderate amount of organelles. The cell exhibits few short filopodia (arrows). The large coarse basophilic granules (1) (specific granules) vary in density and contain vasoactive mediators such as heparin, histamine, sulphated proteoglyca...Poja Histology Collection - Blood & Bone Marrow Subset
22 Basophilic granulocyte (peripheral blood, human)Electron microscopy. The detail shows close to the nucleus characteristic developing basophilic granules (specific granules) (8-13 μm). At thin arrow (↓) a small Golgi area with a small specific granule. At (***) granules with different osmiophilic internal structures. The basophilic granules var...Poja Histology Collection - Blood & Bone Marrow Subset
23 Basophilic granulocyte in peripheral blood smear (human)Stain: May-Grnwald-Giemsa (MGG). The basophilic granulocyte has large, coarse dark purple-stained granules that contain mediators such as eosinophilic chemotactic factors, heparin, histamine, myeloperoxidase. The nuclear lobes are irregular, badly visible and covered by the granules.Poja Histology Collection - Blood & Bone Marrow Subset
24 Basophilic granulocyte in peripheral blood smear (human)Stain: May-Grnwald-Giemsa (MGG). The basophilic granulocyte is characterized by large, coarse, aggregated dark purple granules. The nuclear lobes are usually not very well visible and masked by the granules (see also inset).Poja Histology Collection - Blood & Bone Marrow Subset
25 Basophilic myelocyte in bone marrow smear (human)Stain: May-Grnwald-Giemsa (MGG). The basophilic myelocyte (1) contains dark bluish-purple (metachromatic), coarse granules in the cytoplasm. (2) Platelets.Poja Histology Collection - Blood & Bone Marrow Subset
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