1301 - 1400 of 4,589
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TitleDescriptionSubjectCollection
1301 2nd degree AV block with junctional escapes and capturesSecond degree AV block is present; conducted beats are identified by those QRS's that terminate shorter cycles than the junctional escape cycle; i.e., the 3rd and probably the 4th QRS's are captures; the other QRS's are junctional escapes.Knowledge Weavers ECG
1302 Atrial fibrillation with moderate ventricular response - MarquetteAtrial fibrillation with moderate ventricular response - MarquetteKnowledge Weavers ECG
1303 Ventricular pacing in atrial fibrillation - marquetteVentricular pacing in atrial fibrillation - marquetteKnowledge Weavers ECG
1304 Ventricular pacemaker: demand mode functioningVentricular pacemaker: demand mode functioningKnowledge Weavers ECG
1305 Ventricular escape beat - marquetteVentricular escape beat - marquetteKnowledge Weavers ECG
1306 LAFB: frontal plane leadsLAFB: frontal plane leadsKnowledge Weavers ECG
1307 Old infero-posterior MIOld infero-posterior MIKnowledge Weavers ECG
1308 2nd degree AV block, type IThe 3 rules of classic AV Wenckebach are: 1. decreasing RR intervals until pause; 2. the pause is less than preceding 2 RR intervals; and 3. the RR interval after the pause is greater than the RR interval just prior to pause. Unfortunately, there are many examples of atypical forms of Wenckebach wh...Wenckebach AV BlockKnowledge Weavers ECG
1309 Atrial echosIn this example a typical Wenckebach sequence is interrupted by what looks like a PAC - indicated by red arrows. Atrial echos are more likely, however, because the preceding beat has a long PR interval, a condition that facilitates reentry and echo formation.Knowledge Weavers ECG
1310 Anteroseptal MI with RBBB: precordial leadsAnteroseptal MI with RBBB: precordial leadsKnowledge Weavers ECG
1311 Cardiac conduction system diagram - marquetteCardiac conduction system diagram - marquetteKnowledge Weavers ECG
1312 ST segment depression: precordial leadsST segment depression: precordial leadsKnowledge Weavers ECG
1313 Idioventricular escape rhythmIdioventricular escape rhythmKnowledge Weavers ECG
1314 Unifocal PVCs - marquetteUnifocal PVCs - marquetteKnowledge Weavers ECG
1315 Two Wrongs Sometimes Make a RightThe question mark is over a normal looking QRS that occurs during 2:1 AV block with RBBB. Following this QRS a ventricular escape rhythm takes over. The normal looking beat is actually a fusion beat resulting from simultaneous activation of the ventricles; the sinus impulse enters the left ventric...Knowledge Weavers ECG
1316 WPW type preexcitationNote the short PR and the subtle delta wave at the beginning of the QRS complexes. The delta wave represents early activation of the ventricles in the region where the AV bypass tract inserts. The rest of the QRS is derived from the normal activation sequence using the bundle branches.Knowledge Weavers ECG
1317 Long QT intervalThe QT interval duration is greater than 50% of the RR interval, a good indication that it is prolonged in this patient. Although there are many causes for the long QT, patients with this are at risk for malignant ventricular arrhythmias, syncope, and sudden death.Knowledge Weavers ECG
1318 Wandering atrial pacemakerWandering atrial pacemaker is a benign rhythm change where the pacemaker site shifts from the sinus node into the atrial tissues. P-wave morphology varies with the pacemaker site.Knowledge Weavers ECG
1319 QRS axis = +60 degreesLead aVL is isoelectric; leads II and III are mostly positive. The QRS axis, therefore, is +60 degrees.Knowledge Weavers ECG
1320 Electronic ventricular pacemaker rhythm - marquetteElectronic ventricular pacemaker rhythm - marquetteKnowledge Weavers ECG
1321 High lateral wall MI (seen in aVL)High lateral wall MI (seen in aVL)Knowledge Weavers ECG
1322 Atrial tachycardia - marquetteAtrial tachycardia - marquetteKnowledge Weavers ECG
1323 LVH with StrainLVH with StrainKnowledge Weavers ECG
1324 PAC's with RBBB aberrant conductionPAC's are identified by the arrows. Note that the PP interval surrounding the PAC is less than 2x the basic sinus cycle indicating that the sinus node has been reset by the ectopic P wave. The pause after the PAC, therefore, is incomplete.Knowledge Weavers ECG
1325 1st degree AV blockThe normal PR interval is 0.12 - 0.20 sec, or 120 -to- 200 ms. 1st degree AV block is defined by PR intervals greater than 200 ms. This may be caused by drugs, such as digoxin; excessive vagal tone; ischemia; or intrinsic disease in the AV junction or bundle branch system.Knowledge Weavers ECG
1326 Sore thumbsTwo funny looking premature beats are seen in this rhythm strip. Beat A is preceded by a PAC which distorts the T wave, making this an aberrantly conducted PAC. Beat B is a PVC. The notch on the down slope of the QRS complex clearly identifies this as a PVC and not aberrancy.Knowledge Weavers ECG
1327 AV dissociation by defaultIf the sinus node slows too much a junctional escape pacemaker may take over as indicated by arrows. AV dissociation is incomplete, since the sinus node speeds up and recaptures the entricles.Knowledge Weavers ECG
1328 Atrial tachycardia with 2:1 AV block: a manifestation of digitalis intoxicationAtrial tachycardia with 2:1 AV block: a manifestation of digitalis intoxicationKnowledge Weavers ECG
1329 Accelerated junctional rhythm - marquetteAccelerated junctional rhythm - marquetteKnowledge Weavers ECG
1330 First degree AV block - marquetteFirst degree AV block - marquetteKnowledge Weavers ECG
1331 AV sequential pacemaker - marquette(Summary)Knowledge Weavers ECG
1332 Postero-lateral MI: Fully EvolvedThe true posterior MI is recognized by pathologic R waves in leads V1-2. These are the posterior equivalent of pathologic Q waves (seen from the perspective of the anterior leads). Tall T waves in these same leads are the posterior equivalent of inverted T waves in this fully evolved MI. The loss o...Knowledge Weavers ECG
1333 Atrial tachycardia with 3:2 and 2:1 AV blockThe ectopic atrial rate is 150 bpm. Some of the ectopic P waves are easily seen and indicated by the arrows. Other P waves are burried in the T waves and not so easily identified. Atrial tachycardia with AV block is often a sign of digitalis intoxication. 3:2 and 2:1 AV block is seen in this examp...Knowledge Weavers ECG
1334 RBBB with primary ST-T wave abnormalitiesRBBB is recognized by 1) rR' in V1; 2) QRS duration>0.12s; 3) terminal QRS forces oriented rightwards and anterior. In RBBB the ST-T waves should be oriented opposite to the terminal QRS forces. In this example there areprimary ST-T wave abnormalitiesin leads I, II, aVL, V5, V6. In these leads th...Knowledge Weavers ECG
1335 What are those funny looking beats????The differential diagnosis of funny-looking-beats, or FLB's, primarily considers beats of supraventricular origin with aberrant conduction and ventricular ectopic beats. In this example the two FLB's have an easily seen ectopic P wave before them; therefore these are PAC's with RBBB aberration.Knowledge Weavers ECG
1336 Conceptual framework: aArrhythmias and conduction abnormalitiesConceptual framework: aArrhythmias and conduction abnormalitiesKnowledge Weavers ECG
1337 Atrial flutter with variable AV block - marquetteAtrial flutter with variable AV block - marquetteKnowledge Weavers ECG
1338 Compensatory vs. non-compensatory pauses - marquetteCompensatory vs. non-compensatory pauses - marquetteKnowledge Weavers ECG
1339 Propionyl CoA production from odd-chain fatty acidsBeta-oxidation of fatty acids with an odd number of carbons inthe chain yields the three-carbon propionyl CoA as the final fragment.BiosynthesisKnowledge Weavers Fatty Acids
1340 Transfer of a malonyl group to the acyl carrier peptideDuring fatty acid synthesis the incoming two carbon fragment is introduced as the three-carbon malonyl group. It is added to the -SH group of the acyl carier peptide domain of fatty acid synthase. In a subsequent reaction the carbon shown in green will be lost as bicarbonate ion.Knowledge Weavers Fatty Acids
1341 Transport of fatty acyl CoA into mitochondria by the carnitine shuttleFatty acyl CoA cannot cross the inner mitochondrial membrane, so it is carried in the form of fatty acyl carnitine.Knowledge Weavers Fatty Acids
1342 Hydroxymethylglutaryl CoA lyase reactionIn this mitochondrial process hydroxymethylglutaryl CoA is converted to acetoacetate, a ketone body. Acetyl CoA is another product.Knowledge Weavers Fatty Acids
1343 Acetyl CoA metabolism -- overviewMajor metabolic sources of acetyl CoA and some of the processes in which it serves as a substrate.Knowledge Weavers Fatty Acids
1344 Oleic acid structureOleic acid is a typical monounsaturated fatty acid.Knowledge Weavers Fatty Acids
1345 methylmalonyl CoA mutase reactionIn the metabolism of propionyl CoA L-methylmalonyl CoA is converted to succinate by methylmalonyl CoA mutase. Succinate can then be metabolized throgh the tricarboxylic acid cycle.Knowledge Weavers Fatty Acids
1346 Mammalian fatty acyl synthase dimerThis schematic diagram is intended to show the sequence of enzyme activities in the two subunits of a mammalian fatty acyl synthase dimer. It is not intended to imply anything about the detailed spatial relationships of the activities.Coenzyme A SynthetasesKnowledge Weavers Fatty Acids
1347 Hydration of an enoyl CoAHydration of the double bond is catalyzed by enoyl CoA hydratase. The product is an L-3-hydroxyacyl CoA. This reaction is a step in the beta-oxidation of fatty acids.Knowledge Weavers Fatty Acids
1348 Acetyl CoA structureAcetyl CoA Structure. The thioester bond linking the acetyl group to CoA is ahigh energybond.Knowledge Weavers Fatty Acids
1349 Use of greek letters to designate carbons in fatty acidsThe carbon next to the -COOH group is the alpha carbon; the next one is the beta carbon, and so forth. The carbon most distant from the -COOH group is designated omega. Carbons close to the omega carbon may be designated in relation to it. E.g., the third carbon from the end is omega - 3, and the...NomenclatureKnowledge Weavers Fatty Acids
1350 Acylation of carnitine by a long chain fatty acyl CoALong chain fatty acyl CoA cannot cross the inner mitochondrial membrane to participate in beta-oxidation. The fatty acyl group is therefore transferred to a carrier, carnitine, in a reversible reaction catalyzed by carnitine acyl transferase I. The resulting fatty acyl carnitine crosses the membra...Knowledge Weavers Fatty Acids
1351 Four systems for denoting fatty acidsThere are four commonly used ways of designating fatty acids. The first two columns show samples of names, and the last two columns show systems of abbreviating these names.NomenclatureKnowledge Weavers Fatty Acids
1352 Reduction of 2-enoyl acyl carrier peptideA 2-enoyl acyl group on the acyl carrier peptide is reduced by NADPH in a reaction catalyzed by enoyl acyl carrier peptide reductase.Knowledge Weavers Fatty Acids
1353 methylmalonyl CoA racemase reactionIn the metabolism of propionyl CoA, D-methylmalonyl CoA is produced by a carboxylase reaction. This product must be converted to L-methylmalonyl CoA in order to be metabolized further. The conversion is catalyzed by methylmalonyl CoA racemase.Knowledge Weavers Fatty Acids
1354 Oxidation of a polyunsaturated fatty acid -- part IThe cycles of beta-oxidation prior to the one involving the original Delta-12 double bond act to get past the Delta-9 double bond.Knowledge Weavers Fatty Acids
1355 enoyl CoA isomerase reactionEnoyl CoA isomerase converts a trans-3-enoyl CoA to a trans-2-enoyl CoA. Thus a Delta-9 fatty acyl CoA or the product of the 2,4-dienoyl CoA reductase reaction can proceed through beta-oxidation.Enoyl CoA Isomerase ReactionKnowledge Weavers Fatty Acids
1356 Structures of the ketone bodiesThese are the structures of the ketone bodies. Acetoacetate and beta-hydroxybutyrate are important physiological substrates. Acetone is a byproduct, and is not metabolized further. It is excreted in the urine and in expired air.Knowledge Weavers Fatty Acids
1357 Triacylglycerol structureThe structure of a typical triacylglycerol (triglyceride).Knowledge Weavers Fatty Acids
1358 Dehydrogenation of fatty acyl CoAFatty acyl CoA is dehydrogenated by FAD in a reaction catalyzed by one of the acyl CoA dehydrogenases. Note that the dehydrogenation occurs between the alpha- and beta-carbons.FADKnowledge Weavers Fatty Acids
1359 Reduction of acetoacetateAcetoacetate is reduced by NADH in a reversible reaction catalyzed by beta-hydroxybutyrate dehydrogenase. This reaction is the source of beta-hydroxybutyrate in the blood of individuals with ketosis.Knowledge Weavers Fatty Acids
1360 Hydroxymethylglutaryl CoA synthase reactionThis irreversible reaction occurs in the mitochondria, where it is the first step in ketone body synthesis. It also occurs in the cytoplasm, where it leads to isoprenoid and steroid synthesis.BiosynthesisKnowledge Weavers Fatty Acids
1361 Thiolase reactionThiolase (3-ketoacyl CoA thiolase) cleaves a long chain fatty acyl CoA, forming acetyl CoA and a long chain fatty acyl CoA that is two carbons shorter.Knowledge Weavers Fatty Acids
1362 Beta-oxidation of a delta-9 fatty acyl CoAEnoyl CoA isomerase is required to move the double bond in a Delta-9 fatty acyl CoA to a position where it can continue in beta-oxidation.Knowledge Weavers Fatty Acids
1363 Thiolase reaction with acetoacetyl CoAThiolase (3-ketoacyl CoA thiolase) cleaves acetoacetyl CoA, forming two molecules of acetyl CoA.Knowledge Weavers Fatty Acids
1364 Stearic acid structureStearic acid is a typical long chain saturated fatty acid.Knowledge Weavers Fatty Acids
1365 Fatty acid elongation in mitochondriaThis shows the overall reaction of fatty acid elongation in mitochondria. The process is essentially a reversal of beta-oxidation, except that one NADPH and one NADH are required (beta-oxidation yields two NADH). Mitochondrial fatty acid elongation acts primarily on fatty acyl CoA substrates short...Knowledge Weavers Fatty Acids
1366 Fatty acyl CoA elongation in the endoplasmic reticulumThis shows the overall process of fatty acyl elongation in the endoplasmic reticulum. The process resembles that catalyzed by fatty acyl synthase, but the individual activities appear to be on separate enzymes.Knowledge Weavers Fatty Acids
1367 Propionyl CoA carboxylase reactionPropionyl CoA is metabolized by a process that first converts it to D-methylmalonyl CoA. The reaction is catalyzed by propionyl CoA carboxylase,and requires energy in the form of ATP.BiosynthesisKnowledge Weavers Fatty Acids
1368 Linoleic acid structureLinoleic acid is a typical polyunsaturated fatty acid.Knowledge Weavers Fatty Acids
1369 Reduction of a 2,4-dienoyl CoAThe reduction of 2,4-dienoyl CoA by NADPH is a step in the oxidation of polyunsaturated fatty acids. It is ironic that a reduction reaction is a required step in a process that is oxidative.Knowledge Weavers Fatty Acids
1370 Stearic, oleic and linoleic acid structuresStearic, oleic and linoleic acid structuresKnowledge Weavers Fatty Acids
1371 Complete oxidation of an odd-chain fatty acid -- overviewThis diagram indicates production of propionyl CoA from an odd-chain fatty acid and the subsequent conversion of propionyl CoA to succinyl CoA, which can be metabolized through the citric (tricarboxylic) acid cycle.BiosynthesisKnowledge Weavers Fatty Acids
1372 Initiation of beta-oxidationAn acetyl group is transferred from acetyl CoA to the -SH group of the condensing enzyme domain of fatty acyl synthase, forming acetyl-CE. The reaction is catalyzed by the acyltransferase activity of fatty acyl synthase.Knowledge Weavers Fatty Acids
1373 Fatty acid metabolism -- schematic overviewFatty acids are taken up by cells, where thy may serve as precursors in the synthesis of other compounds, as fuels for energy production, and as substrates for ketone body synthesis. Ketones bodies may then be exported to other tissues, where they can be used for energy production.BiosynthesisKnowledge Weavers Fatty Acids
1374 Condensation of an acyl group with a malonyl groupThe acetyl group displaces the carboxyl of the malonyl group, forming a beta-ketoacyl group. This reaction is catalyzed by beta-ketoacyl Acyl Carrier Peptide synthase. The carboxyl released in the form of bicarbonate regenerates the bicarbonate used earlier in the acetyl CoA carboxylase reaction.Knowledge Weavers Fatty Acids
1375 Essential features of a fatty acidThe essential features of a fatty acid are a long hydrocarbon chain terminating in a carboxylic acid group.Knowledge Weavers Fatty Acids
1376 Corpus luteum cysts exhibit a convoluted lining with luteinized granulosa and theca cells.Corpus luteum of the ovary, medium power. The granulosa cells have undergone proliferation and alteration to lutein cells that produce progesterone. The lutein cells are large and polyhedral and the cytoplasm is foamy and eosinophilic.Knowledge Weavers Human Reproduction
1377 Mucinous cystadenomaThese tumors comprise 20% of all neoplasms, and 50% of ovarian neoplasms found in women less than 20 years of age. They are frequently multiloculated. The favored hypothesis for their origin is metaplastic surface epithelium as they have a predominance of endocervical gland type epithelium.Knowledge Weavers Human Reproduction
1378 Ovarian tumorA large vertical incision allows delivery and excision of an ovarian neoplasm. Pelvic washings for cytology and a frozen section rule out a malignancy. The cyst is excised carefully to avoid spilling contents into the abdomen.Knowledge Weavers Human Reproduction
1379 Ultrasound of placental abruptionThe fetal body and bladder are labeled FB, and BL, respectively.Knowledge Weavers Human Reproduction
1380 Uterine ruptureUterine ruptureKnowledge Weavers Human Reproduction
1381 Brenner tumorSolid and partially cystic epithelial nests are surrounded by a stroma composed of bundles of tightly-packed spindle shaped cells. The epithelial cells are polygonal and of the squamoid type, with pale, eosinophilic cytoplasm and oval nuclei having distinct nuclei and longitudinal grooving, a coffee...Knowledge Weavers Human Reproduction
1382 Mucinous cystadenomaThis tumor weighed 35 pounds.Knowledge Weavers Human Reproduction
1383 Brenner tumorBrenner tumors are comprised of solid to partly cystic epithelial nests surrounded by stroma composed of bundles of tightly packed spindle-shaped cells. The epithelial cells are polygonal and of squamoid type, with pale, eosinophilic cytoplasm and oval nuclei with distinct nucleoli and longitudinal ...Knowledge Weavers Human Reproduction
1384 EstradiolThe structure of ethinyl estradiol and mestranol.Knowledge Weavers Human Reproduction
1385 Mucinous cystadenomaNeglected mucinous cystadenoma may become extremely large.Knowledge Weavers Human Reproduction
1386 Mature cystic teratoma - MicroscopicEctodermal tissue is usually most abundant and represented by: squamous epithelium and appendages, brain tissue, glia, retina, choroid plexus, and ganglia. Mesodermal tissue is represented by bone and cartilage. Endodermal tissue is represented by gastrointestinal and bronchial epithelium and glands...Knowledge Weavers Human Reproduction
1387 HirsutismThis woman has polycystic ovarian syndrome and hyperandrogenemia resulting in hirsutism.Knowledge Weavers Human Reproduction
1388 Structures of acetoxy progestins (pregnane steroids)From C. Matthew Peterson, M.D. Progestogens, Progesterone Antagonists, Progesterone, and Androgens: Synthesis, Classification and Uses, Clinical Obstetrics and Gynecology, 1995; 38: 813-20. The structures of acetoxy progestins (pregnane steroids).Knowledge Weavers Human Reproduction
1389 Serous cystadenomaThese tumors comprise 20% of all ovarian neoplasms. The epithelium is a single layer of regular cuboidal epithelium, with basal nuclei and rare mitoses.Knowledge Weavers Human Reproduction
1390 Congenital adrenal hyperplasia and clitoromegalyCongenital adrenal hyperplasia and clitoromegalyKnowledge Weavers Human Reproduction
1391 Mature cystic teratoma-torsed with adenexal structuresElements of all three germ layers are present: endoderm, mesoderm, and ectoderm. They are classified as germ cell tumors and are thought to arise through parthenogenesis. They are found in the path of migration of the germ cells from the yolk sac to the primitive gonad.PathogenesisKnowledge Weavers Human Reproduction
1392 Total placenta previa: placenta accreta in uterine specimenPlacenta accreta or percreta may be associated with placenta previa especially if the patient has had a previous cesarean section.Knowledge Weavers Human Reproduction
1393 Ovarian follicular scanningOvarian follicular scanning. Ovaries are scanned transvaginally to determine the size of the developing follicles.Knowledge Weavers Human Reproduction
1394 Total placenta previa: schematic of complete placenta previaThe placenta completely covers the internal os of the cervix.Knowledge Weavers Human Reproduction
1395 Abruptio placentaAbruptio placentaKnowledge Weavers Human Reproduction
1396 Contraception for women in their later yearsContraception for women in their later reproductive years.Knowledge Weavers Human Reproduction
1397 Pelvic massA pelvic mass may be present with abdominal distention from the mass, ascities, or both.Abdominal DistentionKnowledge Weavers Human Reproduction
1398 Androgen insensitivityAdapted with permission from Jaffe R.B. Disorders of Sexual Differentiation. In Yen SSC and Jaffe RB, eds, Reproductive Endocrinology, W.B. Saunders Co., Philadelphia, 1986, p 300. An inability to respond to testosterone through a target organ receptor defect in 60-70% and a post-receptor signalling...Knowledge Weavers Human Reproduction
1399 Klinefelter's syndromeAdapted with permission from Grumbach M.M. and Conte F.A.,Disorders of Sexual Differentation. In Williams R.H. ed, Textbook of Endocrinology, W. B.Squanders Co., Philadelphia, 1981, p 451. Males with an XXY karyotype characteristically have long extremities, aeunuchoidal habitus, and gynecomastia.Knowledge Weavers Human Reproduction
1400 Polycystic ovariesPolycystic ovary, high power view: Prominent layer of theca interna cells with extensive luteinization. Atretic follicles are more abundant in the cortex.Knowledge Weavers Human Reproduction
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