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TitleDescriptionSubjectCollection
1 MS Time Lapse MRIMultiple Sclerosis; Serial Brain MRI in Multiple SclerosisNeuro-Ophthalmology Virtual Education Library - Shirley H. Wray Neuro-Ophthalmology Collection: https://novel.utah.edu/Wray/
2 Retinal Microvascular Impairment in Multiple Sclerosis and Dementia (video)The recent advances of ophthalmic imaging techniques, such as the Optic Coherence Tomography Angiography; (OCTA) and the retinal function imager (RFI), enable vascular changes in the posterior segment of the eye; to be qualitatively and quantitatively analyzed. This symposium will provide an overvie...Multiple Sclerosis, DementiaNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
3 Ocular FlutterOcular Flutter; Multiple Sclerosis; Lid Flutter; Multiple Sclerosis Ocular FlutterNeuro-Ophthalmology Virtual Education Library - Shirley H. Wray Neuro-Ophthalmology Collection: https://novel.utah.edu/Wray/
4 Elliptical Pendular Nystagmus in MS𝗢𝗿𝗶𝗴𝗶𝗻𝗮𝗹 𝗗𝗲𝘀𝗰𝗿𝗶𝗽𝘁𝗶𝗼𝗻: This is a 40-yo-woman with MS and bilateral optic nerve disease who presented with a year's long history of oscillopsia, which was related to elliptical pendular nystagmus. The appearance of elliptical nystagmus is the re...Pendular Nystagmus; Multiple SclerosisNeuro-Ophthalmology Virtual Education Library: Dan Gold Neuro-Ophthalmology Collection: https://novel.utah.edu/Gold/
5 Multiple Sclerosis Follow UpDr. Lee lectures medical students on the subject of following up on with a patient with multiple sclerosis.Multiple Sclerosis; Fingolimod; FAMENeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
6 Uhthoff PhenomenonSummary: • Uhthoff phenomenon overview: o Symptoms include vision loss caused by heat, exertion, or exercise o Not necessarily just poor vision, can also lead to numbness or weakness o Seen in people with multiple sclerosis (MS) • Pathophysiology o Seen in people with MS since they rely on regul...Multiple Sclerosis; Vision LossNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
7 "Oh, You Have Metastatic Cancer" (Presentation Video)Hemianopsia; Multiple Sclerosis; Demyelinating DiseasesNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
8 Elliptical NystagmusPrimary Position Elliptical Nystagmus; Multiple SclerosisNeuro-Ophthalmology Virtual Education Library - Shirley H. Wray Neuro-Ophthalmology Collection: https://novel.utah.edu/Wray/
9 Multiple SclerosisToday, we're going to be talking about the neuro-ophthalmology things that we see in patients who have multiple sclerosis. And as you know multiple sclerosis is defined by lesions separated in both space, different locations, and in time. And that can be separated radiographically in space and time ...Multiple Sclerosis; Optic Neuritis; Internuclear OphthalmoplegiaNeuro-Ophthalmology Virtual Education Library: Andrew G. Lee Collection: https://novel.utah.edu/Lee/
10 New Treatments for Multiple SclerosisThe era of disease modifying therapy for Multiple Sclerosis (MS), which began with ACTH in the 1950s, has truly accelerated in the past 2 decades. Neuro-ophthalmologists should be aware of the important recent therapeutic advances that will impact their patients with MS.Multiple Sclerosis; Rituximab; Alemtuzumab; Siponimod; Ocrelizumab
11 MS and the Immune SystemMultiple sclerosis is a multifactorial autoimmune disease of the central nervous system with three primary targets of the brain, spinal cord and optic nerves. Based on monozygotic twin studies, the heritability of MS is 25%.Multiple Sclerosis; Autoimmunity; Genetics; Aging; Sex DifferencesNeuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
12 Therapies for Multiple SclerosisRecent progress makes it clear that we are in a new era regarding therapeutics for multiple sclerosis (MS). After a long history of treating MS symptomatically, the past two decades have brought a new armamentarium of diseasemodifying therapies that modulate the autoimmune response in a variety of w...Multiple Sclerosis; Natalizumab; Fingolimod; Progressive Multifocal LeukoencephalopathyNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
13 We Can Hardly Believe Our EyesA 17 year old man with a history of JME and learning disability developed fatigue and right-sided numbness and weakness one month after an asymptomatic COVID infection. In the ED, he was agitated, requiring sedation. MRI brain demonstrated large, nodular, incomplete ring enhancing supratentorial whi...Mitochondrial Disorders; Optic Neuropathy; Multiple Sclerosis (MS)Neuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
14 MS Treatment/Immune System TargetsFirst-generation injectable MS DMTs - Beta interferons and glatiramer acetate were the first MS disease modifying therapies, FDA-approved in the 1990s. They are only moderately effective compared to more modern MS treatment options, but they are felt to be generally safe and well-tolerated. Injectio...Demyelination; Multiple Sclerosis; Disease-modifying Therapy; Relapsing; ProgressiveNeuro-Ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
15 Neuro-Ophthalmic Consequences of Medications for Multiple Sclerosis: The Good, The Bad, The Ugly and The Unknown (video)The landscape of therapies for multiple sclerosis (MS) is constantly shifting. Currently, there are 11 FDA approved agents for chronic disease treatment, multiple drugs in clinical trials for acute and chronic disease management and numerous compounds used for symptom control. Beyond treating patien...Multiple Sclerosis, Medication complications, Macular Edema, Thyroid eye disease, InfectionNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
16 Adult Optic Neuritis (Video)LEARNING OBJECTIVES: 1. Describe the clinical characteristics and outcomes of optic neuritis in adults. 2. Explain the natural history of optic neuritis (and the associated risk of multiple sclerosis), based on data from the Optic Neuritis Treatment Trial (ONTT), the Longitudinal Optic Neuritis Stud...Neuro-Ophthalmology; Optic Neuritis; Myelin Oligodendrocyte Glycoprotein; Neuromyelitis Optica; Multiple SclerosisNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
17 Downbeat Nystagmus - Periodic Alternating NystagmusDownbeat Nystagmus; Periodic Alternating Nystagmus; Multiple Sclerosis; Primary Position Downbeat NystagmusNeuro-Ophthalmology Virtual Education Library - Shirley H. Wray Neuro-Ophthalmology Collection: https://novel.utah.edu/Wray/
18 Neuro-Ophthalmology of Multiple SclerosisMultiple Sclerosis (MS) is the most common neurological disease in young people with an average age of onset between 15 and 35 years old. MS is an autoimmune inflammatory condition that causes demyelinating lesions in the CNS. The diagnosis is clinical, but MRI is typically used to support the diagn...Multiple Sclerosis; Optic Neuritis; Uveitis; Internuclear Ophthalmoplegia; Nystagmus; Steroids; Demyelinating; AutoimmuneNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
19 New Therapies for Multiple Sclerosis, Beyond the ABCs (video)As of 2015, multiple sclerosis (MS) is the only treatable neurodegenerative disease. It has frequent visual manifestations, most of which are in the clinical purview of neuro-ophthalmologists. This syllabus is intended to update neuro-ophthalmologists about new data surrounding, the new and emerging...Multiple Sclerosis; Monoclonal Antibodies; Immunotherapy/Immune modulators; Injectable Therapies; Oral AgentsNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
20 Bilateral Internuclear Ophthalmoplegia (INO)Bilateral Internuclear Ophthalmoplegia; Abducting Nystagmus; Upbeat Nystagmus on Upgaze; Oscillopsia; Multiple SclerosisNeuro-Ophthalmology Virtual Education Library - Shirley H. Wray Neuro-Ophthalmology Collection: https://novel.utah.edu/Wray/
21 Pediatric Optic Neuritis (Video)LEARNING OBJECTIVES: 1. Describe the clinical characteristics and outcomes of optic neuritis in children. 2. Formulate a diagnostic workup for a pediatric patient with optic neuritis. 3. Describe the outcomes associated with anti-aquaporin-4 and anti-myelin oligodendrocyte glycoprotein antibody posi...Pediatric Neuro-Ophthalmology; Optic Neuritis; Neuromyelitis Optica; Myelin Oligodendrocyte Glycoprotein; Multiple SclerosisNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
22 Pendular Vertical OscillationsPendular Vertical Oscillations; Rotary Nystagmus; Saccadic Dysmetria; Oscillopsia; Multiple Sclerosis; Torsional NystagmusNeuro-Ophthalmology Virtual Education Library - Shirley H. Wray Neuro-Ophthalmology Collection: https://novel.utah.edu/Wray/
23 Get Me Out of Here; It's Too Crowded (Presentation Video)Leukemia, Promyelocytic, Acute; Granulocyte Precursor Cells; Optic Neuritis; Pupil Disorders; Scotoma; Multiple SclerosisNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
24 Jacobson Lecture - Optic Neuritis: Past, Present, and Future (Video)OCT has provided a basis for correlating structural aspects of anterior visual pathway axonal and neuronal loss with visual function in ON as well as in MS. It is now known that patients with MS have thinning of the retinal nerve fiber layer (RNFL, axons) and ganglion cell/inner plexiform layer (GCL...Multiple Sclerosis; Optic Neuritis; Optical Coherence Tomography; Low Contrast Letter Acuity; Magnetic Resonance ImagingNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
25 Pediatric Optic Neuritis (video)Pediatric optic neuritis differs from adult optic neuritis because the condition in children is commonly bilateral,; associated with optic disc swelling, and characterized by severe vision loss. The risk of developing multiple sclerosis (MS) is related to the presence of white matter lesions in the ...Pediatric Optic Neuritis, Multiple Sclerosis, Anti-MOG Antibodies, Acute Disseminated Encephalomyelitis (ADEM), NMO Spectrum DisorderNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
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