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TitleCreatorDescriptionSubjectImaging
1 Acute Retrobulbar Optical NeuropathyAlfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCPPT covering acute retrobulbar optic neuropathy, including ischemic, inflammatory, anterior ischemic optic neuropathy (AION) and non-arteritic anterior ischemic optic neuropathy (NAION); includes brainscan images for optic neuritis and multiple sclerosis; optic disk with LHON and PION. Anatomy: Opt...Optic Neuropathy, Ischemic; Giant Cell Arteritis; Edema; Multiple sclerosis; Optic Atrophy, Hereditary, Leber; Ischemia; Hypotension; Edema; Optic Neuritis; Optic Nerve; Interferon-Beta-1a; Diseases of the Optic Nerve
2 Optic Nerve Sheath Decompression in the Management of Optic NeuropathiesAlfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCA slide presentation with several images of optic disc, normal and with edema. Anatomy: Optic nerve; Optic disc. Disease/Diagnosis: Optic neuropathy, Ischemic; Pseudotumor cerebri; Papilledema. Treatment: Decompression, Surgical.Decompression, Surgical; Optic Neuropathy, Ischemic; Pseudotumor Cerebri; Papilledema; Optic Nerve; Optic Disc
3 Toxic Optic Neuropathies: Mitochondria and the RGCAlfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCDiscussion of various forms of mitrochondrial optic neuropathies and how to distinguish from toxic optic neuropathies, with examples from Cuba and Brazil; includes images of optic disc showing LHON. Presenting Symptom: Blindness; Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia. Anatomy: Optic ne...Optic Nerve; Optic Disc; Retinal Ganglion Cells; Reactive Oxygen Species; Blindness; Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia; Optic Atrophy, Autosomal Dominant; Optic Atrophy, Hereditary, Leber; Toxic Optic Neuropathy; Alcoholic Neuropathy; Brazil; Cuba; Linezolid; Ethambutol; Tomography...
4 Viagra and Vision Loss: Does Sex Make You Blind?Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCAt a formal debate during a meeting in Canada in Sept. 2006, Sadun was assigned the role of arguing the case FOR a connection between taking phosphodiesterase 5 (PDE5) inhibitors and developing anterior ischemic optic neuropathy. Presenting Symptom: Hypotension. Anatomy: Optic nerve; Optic disc; Cyc...Sildenafil; Vardenafil; Tadalafil; Viagra; Levitra; Cialis; Optic Neuropathy, Ischemic; Toxic Optic Neuropathy; Optic Nerve; Optic Disc; Cyclic Nucleotide Phosphodiesterases, Type 5; Hypotension
5 Viagra and Vision Loss: Does Sex Make You Blind?Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCPresenting symptom: Hypotension. Anatomy: Optic nerve; Optic disc; Cyclic Nucleotide Phosphodiesterases, Type 5. Disease/Diagnosis: Optic Neuropathy, Ischemic; Toxic optic neuropathy.Sildenafil; Vardenafil; Tadalafil; Viagra; Levitra; Cialis; Optic Neuropathy, Ischemic; Toxic Optic Neuropathy; Optic Nerve; Optic Disc; Cyclic Nucleotide Phosphodiesterases, Type 5; Hypotension
6 The Neuro-Ophthalmic Manifestations of DiabetesAlfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCAnatomy: Orbit; Optic nerve. Disease/Diagnosis: Diabetes; Mucormycosis; Acidosis; Hypoplasia of the optic nerve; Diabetes mellitus; Diabetic optic papillopathy; Optic neuropathy, Ischemic; Diabetic optic atrophy; Ophthalmoplegia; Arteritis; Diabetic ketoacidosis; Orbital cellulitis. Treatment: Debri...Diabetes; Mucormycosis; Acidosis; Hypoplasia of the Optic Nerve; Diabetes Mellitus; Diabetic Optic Papillopathy; Optic Neuropathy, Ischemic; Diabetic Optic Atrophy; Ophthalmoplegia; Arteritis; Diabetic Ketoacidosis; Orbital Cellulitis; Hyphae; Orbit; Optic Nerve; Debridement
7 The Diagnostic Workup in Patients With Optic Neuropathies (Metodo diagnostico)Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCSlideshow presentation with images of optic disc with edema and "Positive temporal artery biopsy". Presenting Symptom: Hyperopia; Metamorphopsia. Anatomy: Optic nerve; Macula Lutea; Optic disc. Disease/Diagnosis: Optic neuritis; Macular edema; Optic neuropathy, Ischemic.Hyperopia; Metamorphopsia; Optic Nerve; Macula Lutea; Optic Disc; Optic Neuritis; Macular Edema; Optic Neuropathy, Ischemic
8 How Mitochondria Orchestrate the Death of RGCs : From Brazil to Tuebingen to Rochester 2007Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCSlides showing LHON and Kjer's optic atrophy and images of optic disk with LHON. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia; Blindness.Optic Nerve; Retina; Retinal Ganglion Cells; Reactive Oxygen Species; Scotoma; Telangiectasis; Apoptosis; Cell Death; Dyschromatopsia; Blindness; Optic Atrophy; Hereditary; Leber; Leber's Optic Neuropathy
9 How Strong is the Case for an Association Between PDE5 Inhibitors and NAION?Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCAnatomy: Optic nerve. Disease/Diagnosis: Optic Neuropathy, Ischemic; Toxic optic neuropathy. Presenting Symptom: Ischemia; Scotoma; Dyschromatopsia.Optic Neuropathy, Ischemic; Toxic Optic Neuropathy; Ischemia; Scotoma; Dyschromatopsia; Optic Nerve; Phosphodiesterase 5 Inhibitor; Viagra
10 Mitochondria and the RGCAlfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCDiscussion of various forms of mitrochondrial optic neuropathies and how to distinguish from toxic optic neuropathies, with examples from Cuba and Brazil. Presenting Symptom: Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia. Anatomy: Optic nerve; Optic disc; Retinal ganglion cells; Reactive oxyge...Optic Nerve; Optic Disc; Retinal Ganglion Cells; Reactive Oxygen Species; Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia; Optic Atrophy; Autosomal Dominant; Optic Atrophy; Hereditary; Leber; Toxic Optic Neuropathy; Brazil; Cuba; Linezolid
11 Mitochondrial Optic Neuropathy: Mitochondria as Gatekeepers for ApoptosisAlfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCAnatomy: Optic nerve; Retina; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber; Toxic optic neuropathy. Presenting Symptom: Scotoma; Dyschromatopsia.Apoptosis; Cell Death; Optic Atrophy, Hereditary, Leber; Toxic Optic Neuropathy; Optic Nerve; Retina; Retinal Ganglion Cells; Reactive Oxygen Species; Amiodarone; Scotoma; Dyschromatopsia
12 Pupils and the Neuro-Ophthalmic Manifestations of DiabetesAlfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCPresentation given in Italy on diagnosing neuro-opthalmic complications of diabetes with several views of the optic disc. Presenting symptom: Diplopia; Anisocoria; Ptosis; Horner syndrome; Adie syndrome. Anatomy: Pupil; Optic disc; Optic nerve. Disease/Diagnosis: Diabetes; Mucormycosis; Acidosis; Hy...Pupil; Optic Disc; Optic Nerve; Diplopia; Anisocoria; Ptosis; Horner Syndrome; Adie Syndrome; Diabetes; Mucormycosis; Acidosis; Hypoplasia of the Optic Nerve; Diabetes Mellitus; Diabetic Optic Papillopathy; Optic Neuropathy, Ischemic; Diabetic Optic Atrophy; Ophthalmoplegia; Diabetic Ketoacidosis; D...
13 Toxic Optic Neuropathies: How Much Evidence Should it Take to Convict?Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCA critique of claims that the drug Amiodarone causes optic neuropathies. Presenting Symptom: Scotoma; Dyschromatopsia. Anatomy: Optic nerve. Disease/Diagnosis: Toxic optic neuropathy.Amiodarone; Linezolid; Scotoma; Dyschromatopsia; Toxic Optic Neuropathy
14 The Clinical Spectrum of Amiodarone-Associated Optic NeuropathyAlfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCSadun's response to a paper by L.N. Johnson, G.B. Kroheld, and E.R. Thomas at 2004 AAO meeting. Anatomy: Optic nerve. Disease/Diagnosis: Optic nerve diseases; Optic neuropathy, IschemicAmiodarone; Optic Neuropathy, Ischemic
15 Atypical Optic NeuropathiesAlfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCA discussion of atypical optic neuropathies. Anatomy: Optic nerve; Optic disc. Pathology: Slides showing LHON. Disease/Diagnosis: Optic neuropathy, Ischemic; Optic atrophy, Hereditary, Leber; Toxic optic neuropathy. Presenting Symptom: Optic neuritis; Eye hemorrhage; Retinal vasculitis; Dyschromatop...Brazil; Cuba; Ethambutol; Optic Neuritis; Eye Hemorrhage; Retinal Vasculitis; Dyschromatopsia; Scotoma; Ataxia; Paresthesia; Hyporeflexia; Optic Nerve; Optic Disc; Optic Neuropathy, Ischemic; Optic Atrophy, Hereditary, Leber; Toxic Optic Neuropathy
16 The Diagnostic Workup in Patients With Optic NeuropathiesAlfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCSlideshow presentation with images of optic disc with edema and optic atrophy. Presenting Symptom: Telangiectasis; Dyschromatopsia; Scotoma. Anatomy: Optic nerve; Optic disc; Phosphopyruvate Hydratase; Enolase. Disease/Diagnosis: Optic neuritis; Macular edema; Optic neuropathy, Ischemic; Optic atrop...Telangiectasis; Dyschromatopsia; Scotoma; Optic Nerve; Optic Disc; Phosphopyruvate Hydratase; Enolase; Optic Neuritis; Macular Edema; Optic Neuropathy, Ischemic; Optic Atrophy, Hereditary
17 Posterior Ischemic Optic NeuropathyAlfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USCDiscusses opthalmic complications of surgery, with example of shock-induced Posterior Ischemic Optic Neuropathy following a hysterectomy. Presenting Symptom: Ischemia; Hypotension. Anatomy: Optic nerve. Disease/Diagnosis: Optic neuropathy, Ischemic; Hematoma; Edema.Optic Neuropathy, Ischemic; Hematoma; Edema; Ischemia; Hypotension; Optic Nerve; Posterior Ischemic Optic Neuropathy
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