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176 Role of Thrombocytosis in Diagnosis of Giant Cell Arteritis and Differentiation from Nonarteritic Anterior Ischemic Optic NeuropathyGiant cell arteritis (GCA) can cause devastating vision loss if left undiagnosed. Traditionally, erythrocyte sedimentation rate (ESR), and more recently C-reactive protein (CRP) have been serum acute phase reactants used to make the diagnosis. Thrombocytosis, or elevated platelet count, has also bee...thrombocytosis; giant cell arteritis; anterior ischemic optic neuropathyNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
177 Treatment of Non-arteritic Anterior Ischemic Optic Neuropathy (NAION): Review of the LiteratureDespite a large number of publications, the treatment of NAION remains controversial.ischemic optic neuropathy; nonarteritic anterior ischemic optic neuropathy; optic neuropathy; steroids; Ischemic Optic Neuropathy Decompression Trial (IONDT)Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
178 Validation of an Animal Model for Non-arteritic Anterior Ischemic Optic NeuropathyNon-arteritic anterior ischemic optic neuropathy (NAION) is a potentially visually devastating disease process in which there is disruption in the arterial blood supply to the optic nerve head, causing ischemic injury to the retinal ganglion cellaxons, resulting in loss of visual field and visual ac...ischemic optic neuropathy; neuroprotection; animal modelNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
179 Visual Recovery and Optical Coherence Tomography (OCT) Changes Following Treatment of Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) with Levodopa Alone or in Combination with Allopurinol and TetracyclineTo determine the effectiveness of levodopa alone or in combination with allopurinol and tetracycline on visual acuity, visual field, and retinal nerve fiber layer (RNFL) thickness in eyes affected by NAION.Levodopa; Allopurinol; Tetracycline; Non-Arteritic Anterior Ischemic Optic Neuropathy; Visual Acuity; Visual Field; Retinal Nerve Fiber Layer ThicknessNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
180 Anterior Ischemic Optic Neuropathy (PowerPoint)curriculum_fellowThe patient is a 62-year-old female who presented in August 1996 with visual loss OD that she first noted as loss of her superior field in May 1996. She felt that it had been static since, and perhaps was even a little better in the week before she was seen. There was no pain, even with ocular rotat...Nonarteritic Ischemic Optic Neuropathy ; Anterior Ischemic Optic NeuropathyNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
181 New Treatments in Neuro-Ophthalmology: The Role for EvidenceIC-H2eiii-critical-review-of-literature; IC-H3a-read-and-analyze-scientific-articlesDrug Approval; Glucocorticoids / therapeutic use; Humans; Neurology / methods; Ophthalmology / methods; Optic Neuropathy, Ischemic / drug therapy; Physicians / ethicsNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
182 Early Diagnosis of Subclinical Interferon Alpha-Associated Optic Neuropathy Using Fluorescein AngiographyAntiviral Agents; Blood Sedimentation; C-Reactive Protein; Early Diagnosis; Fluorescein Angiography; Hepatitis C; Humans; Interferon-alpha; Male; Middle Older people; Optic Nerve Diseases; Viral Load
183 Intravitreal Triamcinolone or Bevacizumab for Nonarteritic Anterior Ischemic Optic NeuropathyAngiogenesis Inhibitors, administration & dosage; Animals; Anti-Inflammatory Agents, administration & dosage; Antibodies, Monoclonal, administration & dosage; Disease Models, Animal; Humans; Injections; Ophthalmologic Surgical Procedures, adverse effects; Optic Nerve, drug effects; Optic Nerve, phys...
184 Is Intravitreal Bevacizumab an Effective Treatment Option for Nonarteritic Anterior Ischemic Optic NeuropathyOptic Neuropathy, Ischemic; Papilledema; Bevacizumab; Optic Atrophy
185 Is Intravitreal Bevacizumab an Effective Treatment Option for Nonarteritic Anterior Ischemic Optic NeuropathyOptic Neuropathy, Ischemic; Papilledema; Bevacizumab; Optic Atrophy
186 Ischemic optic neuropathy of the young.
187 Acute Retrobulbar Optical Neuropathycurriculum_fellow; KBDdiseasesoftheopticnervePPT covering acute retrobulbar optic neuropathy, including ischemic, inflammatory, anterior ischemic optic neuropathy (AION) and non-arteritic anterior ischemic optic neuropathy (NAION); includes brainscan images for optic neuritis and multiple sclerosis; optic disk with LHON and PION. Anatomy: Opt...Optic Neuropathy, Ischemic; Giant Cell Arteritis; Edema; Multiple Sclerosis; Optic Atrophy, Hereditary, Leber; Ischemia; Hypotension; Edema; Optic Neuritis; Optic Nerve; Interferon-Beta-1a; Diseases of the Optic NerveNeuro-Ophthalmology Virtual Education Library - Alfredo A. Sadun Neuro-Ophthalmology Collection: https://novel.utah.edu/Sadun/
188 High Sensitivity C-Reactive Protein Measurements in Patients with Non Arteritic Anterior Ischemic Optic Neuropathy, a Clue to the Presence of a Microinflammatory ResponseNon arteritic anterior ischemic optic neuropathy is the most common cause for acute optic neuropathy in the elderly. The incidence of atherothrombotic risk factors in these individuals, including diabetes mellitus and hypertension, raises the possibility of common pathological mechanisms that contri...c reactive protein, ischemic optic neuropathyNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
189 Measurement of Optic Nerve Blood Velocity as a Function of Age in Normal SubjectsOptic nerve blood flow is thought to be an important factor in the development of anterior ischemic optic neuropathy. We measured the widths of Doppier-broadened frequency spectra of laser light sacttered from selected sites on the optic nerve head in 22 normal subjects between the ages of 16 and ...Optic Nerve Blood Flow; Anterior Ischemic Optic Neuropathy; Blood Flow, Age; Age Related Cerebral BloodflowNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
190 Retinal Ganglion Cell Apoptosis in AIONWe attempted to identify retinal ganglion cells undergoing apoptosis, a form of programmed cell death, in an eye of a patient with anterior ischemic optic neuropathy (AION). A 70-year-old right-handed white man woke up with painless loss of vision OS after thromboembolectomy of an aorto-femoral graf...Retinal Ganglion Cell; Aptosis; Anterior Ischemic Optic Neuropathy; Terminal Deoxynucleotide Transferase UTP-biotin End Nick LabelingNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
191 Variability of the RAPD Within a DayTo study the fluctuations of the relative afferent pupillary defect (RAPD) within a day. 10 normal subjects, 5 patients with previous anterior ischemic optic neuropathy (AION) and one patient with strabismic amblyopia underwent 5 sequential RAPD determinations at 8 am, noon and 4 pm (15 trials in on...Relative Afferent Pupillary Defect; Anterior Ischemic Optic Neuropathy; Strabismic AmblyopiaNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
192 Should Aspirin Be Prescribed to Prevent Recurrence in Nonarteritic Anterior Ischemic Optic Neuropathy
193 Peripapillary Choroidal Vascularity and Visual Correlates in Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)The peripapillary choroid shares a blood supply with and is directly apposed to the optic nerve, and therefore may contribute to the pathogenesis of non-arteritic anterior ischemic optic neuropathy (NAION). Prior studies evaluating peripapillary choroidal thickness (PCT) and choroidal vascularity in...Optic Neuropathy; Perimetry; Visual FieldsNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
194 Structure-Function Analysis of Nonarteritic Anterior Ischemic Optic Neuropathy and Age-Related Differences in OutcomeAdult; Older people; Aging; Cross-Sectional Studies; Female; Humans; Male; Middle Older people; Optic Disk; Optic Neuropathy, Ischemic; ROC Curve; Retinal Ganglion Cells; Retrospective Studies; Tomography, Optical Coherence; Visual Acuity; Visual Field Tests; Visual Fields
195 24 Hour Blood Pressure Monitoring in Patients with Non-arteritic Anterior Ischemic Optic NeuropathyTemporary severe hypoperfusion of the optic nerve head with subsequent ischemia is believed to be the pathogenic mechanism in non-arteritic AION. Patients often report their visual loss upon awakening. It has thus been proposed that nocturnal hypotension may be a pathogenic factor both in normotensi...Blood Pressure Monitoring; Non-Arteritic Anterior Ischemic Optic Neuropathy; Hypoperfusion; Optic Nerve Head; IschemiaNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
196 50% of Non-Arteritic Anterior Ischemic Optic Neuropathy Occurs between 40-55 Years Old"Non-arteritic ischemic optic neuropathy (NAION) is the most common acute optic neuropathy in those older than 50.1-2 and young onset NAION has been reported in 4-23% of patients.1-4 Aging is a risk factor for NAION, and the normal rate of retinal ganglion cell axonal loss triples after 50.5 The aim...NAION, Age, Risk Factors, OCT, Visual FieldNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
197 Dimensions of the Optic Nerve Head Neural Canal Using Enhanced Depth Imaging Optical Coherence Tomography in Non-Arteritic Ischemic Optic Neuropathy Compared to Normal SubjectsAn anatomically crowded scleral canal has been linked to the development of non-arteritic anterior ischemic optic neuropathy (NAION). Previous authors have described the superficial characteristics of a "disc at risk" in NAION. We sought to investigate the deeper structures of the optic nerve head n...Non-Arteritic Anterior Ischemic Optic Neuropathy; Enhanced Depth Imaging (EDI); Optical Coherence Tomography; Lamina Cribrosa; Disc at RiskNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
198 Laser-induced Optic Neuropathy as A Model to Study Neuro-protectionNonarteritic Anterior Ischemic Optic Neuropathy (NAION) is believed to result from insufficient blood flow to the optic nerve head. However, the precise mechanism of ischemia remains unclear. A successful experimental animal model would help us better understand the pathophysiology of the disease. T...Nonarteritic Anterior Ischemic Optic Neuropathy; Optic Nerve Head; Laser-Induced Optic Neuropathy; Neuro-Protection Animal Model; Mesoporphyrin IX; Photodynamic TherapyNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
199 Myocarditis and Arteritic Anterior Ischemic Optic Neuropathy Secondary to Giant Cell Arteritis (.pdf)Giant cell arteritis (GCA) is a primary vasculitis of medium and large vessels with a broad range of clinical presentations. Myocarditis is a rare known manifestation of GCA. We present a case of a 67 year old man who presented with acute systolic heart failure of unknown etiology. Development of ar...Giant Cell Arteritis, Arteritis Ischemic Optic Neuropathy, Myocarditis, HeadacheNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
200 Use of the Multifocal ERG to Differentiate Arteritic from Non-arteritic Anterior Ischemic Optic Neuropathy (AION)The differentiation of non-arteritic AION from arteritic AION due to giant cell arteritis is usually based on one or more of the following: optic nerve appearance, preceding amaurosis, bilateral involvement, systemic symptoms, serum laboratory tests, and ultimately a positive temporal artery biopsy....giant cell arteritis; anterior ischemic optic neuropathy; multifocal electroretinographyNeuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
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