The Alfredo A. Sadun Neuro-Ophthalmology Collection: A Professor of Ophthalmology and Neurological Surgery at the USC Keck School of Medicine, Dr. Sadun with a team of researchers at the Doheny Eye Institute pioneered research in optic nerve dysfunction in patients with Alzheimer's disease. Contains his "100 best lectures." Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor Ophthalmology & Neurological Surgery, Doheny Eye Institute, Keck School of Medicine at USC.
NOVEL: https://novel.utah.edu/
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| Title | Creator | Description | Subject | ||
|---|---|---|---|---|---|
| 51 |
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Mitochondria and the RGC | Alfredo A. Sadun, MD, PhD | Discussion of various forms of mitrochondrial optic neuropathies and how to distinguish from toxic optic neuropathies, with examples from Cuba and Brazil. Presenting Symptom: Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia. Anatomy: Optic nerve; Optic disc; Retinal ganglion cells; Reactive oxyge... | Optic Nerve; Optic Disc; Retinal Ganglion Cells; Reactive Oxygen Species; Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia; Optic Atrophy; Autosomal Dominant; Optic Atrophy; Hereditary; Leber; Toxic Optic Neuropathy; Brazil; Cuba; Linezolid |
| 52 |
 |
Mitochondrial Optic Neuropathies (MON) | Alfredo A. Sadun, MD, PhD | Combination of two presentations on optic nerve diseases, covering the cases in Cuba and Brazil. Titles: Cuban epidemic of optic neuopathy: even zealots must eat, or, Conversations with Castro and Leber's hereditary optic neuropathy: a very large new pedigree in Brazil; includes several images of ... | Optic Nerve Diseases; Optic Atrophy, Hereditary, Leber; Blindness; Alcoholic Neuropathy; Cuba; Castro, Fidel; Folate; Brazil; Optic Nerve; Optic Disk; Retinal Ganglion Cells; Apoptosis; Cell Death |
| 53 |
 |
Mitochondrial Optic Neuropathy: Mitochondria as Gatekeepers for Apoptosis | Alfredo A. Sadun, MD, PhD | Presentation at Harvard in 2006, focussing on Leber's Heriditary Optic Neuropathy; includes several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells. Disease/Diagnosis: Optic nerve diseases; Optic Atrophy, Hereditary, Leber. Presenting Symptom:... | Scotoma; Dyschromatopsia; Ataxia; Hyporeflexia; Optic Nerve Diseases; Optic Atrophy, Hereditary, Leber; Cuba; Brazil; Optic Nerve; Optic Disk; Retinal Ganglion Cells; Apoptosis; Cell Death; Ethambutol |
| 54 |
 |
Mitochondrial Optic Neuropathy: Mitochondria as Gatekeepers for Apoptosis | Alfredo A. Sadun, MD, PhD | Anatomy: Optic nerve; Retina; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber; Toxic optic neuropathy. Presenting Symptom: Scotoma; Dyschromatopsia. | Apoptosis; Cell Death; Optic Atrophy, Hereditary, Leber; Toxic Optic Neuropathy; Optic Nerve; Retina; Retinal Ganglion Cells; Reactive Oxygen Species; Amiodarone; Scotoma; Dyschromatopsia |
| 55 |
 |
The Neuro-Ophthalmic Manifestations of Diabetes | Alfredo A. Sadun, MD, PhD | Anatomy: Orbit; Optic nerve. Disease/Diagnosis: Diabetes; Mucormycosis; Acidosis; Hypoplasia of the optic nerve; Diabetes mellitus; Diabetic optic papillopathy; Optic neuropathy, Ischemic; Diabetic optic atrophy; Ophthalmoplegia; Arteritis; Diabetic ketoacidosis; Orbital cellulitis. Treatment: Debri... | Diabetes; Mucormycosis; Acidosis; Hypoplasia of the Optic Nerve; Diabetes Mellitus; Diabetic Optic Papillopathy; Optic Neuropathy, Ischemic; Diabetic Optic Atrophy; Ophthalmoplegia; Arteritis; Diabetic Ketoacidosis; Orbital Cellulitis; Hyphae; Orbit; Optic Nerve; Debridement |
| 56 |
 |
Neuro-Surgical Approaches to the Orbit | Alfredo A. Sadun, MD, PhD | Discusses specifics of various approaches to surgical treatment of lesions, including transcranial and transfrontal orbitotomies; neuroimagery scans from before and after operation for meningioma. Presenting Symptom: Proptosis. Anatomy: Orbit; Optic nerve sheath. Disease/Diagnosis: Meningioma; Heman... | Coloboma; Aplasia; Proptosis; Orbit; Optic Nerve Sheath; Meningioma; Hemangiopericytoma; Neurosurgery; Osteotomy |
| 57 |
 |
Neuroprotection = Apoptosis of Retinal Ganglion Cells | Alfredo A. Sadun, MD, PhD | Slide presentation with several microscopic images demonstrating cell death, LHON, AIDS. Presenting Symptom: Blindness; Ischemia; Retinal detachment. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Phosphopyruvate Hydratase. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber; Acquired Immunod... | Optic Nerve; Retina; Retinal Ganglion Cells; Phosphopyruvate Hydratase; Apoptosis; Cell Death; Blindness; Ischemia; Retinal Detachment; Optic Atrophy; Hereditary; Leber; Acquired Immunodeficiency Syndrome |
| 58 |
 |
Office Techniques for Detecting Optic Nerve Disease | Alfredo A. Sadun, MD, PhD | Demonstration of brightness sense testing and of computer-generated graphics for Amsler grid testing. Presenting Symptom: Scotoma; Metamorphopsia. Anatomy: Optic nerve; Retina; Macula lutea. Disease/Diagnosis: Glaucoma; Optic neuritis; Macular degeneration. | Color Vision; Glaucoma; Macular Degeneration; Optic Neuritis; Scotoma; Metamorphopsia; Optic Nerve; Retina; Macula Lutea |
| 59 |
 |
On Being a Program Director | Alfredo A. Sadun, MD, PhD | Speech on the occasion of receiving the first Straatsma Award for Excellence in Resident Education in 2003. | Opthalmology; Medical Education; Internship and Residency |
| 60 |
 |
Optic Chiasm and Anterior Visual Pathways | Alfredo A. Sadun, MD, PhD | Anatomy: Optic chiasm; Visual cortex; Geniculate bodies | Optic Chiasm; Visual Cortex; Geniculate Bodies; AVP Optic Tract; AVP Lateral Geniculate; AVP Optic Radiations; AVP Calcarine Cortex; AVP Association Areas; AVP Optic Chiasm |
| 61 |
 |
Optic Disc Edema: Evaluating the Swollen Disc | Alfredo A. Sadun, MD, PhD | Presentation at AAO 2006 meeting, distinguishing Optic disc edema from papilledema; includes several images of optic disc, normal and with edema and papilledema. Anatomy: Optic disc. Disease/Diagnosis: Retinal edema; Papilledema | Optic Disc; Retinal Edema; Papilledema; Raised Intracranial Pressure |
| 62 |
 |
Optic Disc Edema: Evaluating the Swollen Disc | Alfredo A. Sadun, MD, PhD | Presentation at AAO 2007 meeting, distinguishing Optic disc edema from papilledema. Includes several images of optic disc, normal and with edema and papilledema. Anatomy: Optic disc. Disease/Diagnosis: Retinal edema; Papilledema | Optic Disc; Retinal Edema; Papilledema; Management of Intracranial Hypertension |
| 63 |
 |
Optic Nerve Regeneration | Alfredo A. Sadun, MD, PhD | A slide presentation with three sets of 3 views increasing magnification. Anatomy: Optic nerve; Retina. Disease/Diagnosis: Optic neuropathy, Ischemic; Retrograde degeneration; Necrosis. Treatment: Cerestat; Aptiganel; Memantine; Riluzole. | Nerve Regeneration; Optic Nerve; Retina; Retrograde Degeneration; Necrosis; Apoptosis; Cell Death; Cerestat; Aptiganel; Memantine; Riluzole |
| 64 |
 |
Optic Nerve Sheath Decompression in the Management of Optic Neuropathies | Alfredo A. Sadun, MD, PhD | A slide presentation with several images of optic disc, normal and with edema. Anatomy: Optic nerve; Optic disc. Disease/Diagnosis: Optic neuropathy, Ischemic; Pseudotumor cerebri; Papilledema. Treatment: Decompression, Surgical. | Decompression, Surgical; Optic Neuropathy, Ischemic; Pseudotumor Cerebri; Papilledema; Optic Nerve; Optic Disc |
| 65 |
 |
Optic Nerve Tumors: Diagnosis and Therapy | Alfredo A. Sadun, MD, PhD | Powerppoint lecture covers a patient case, differential diagnosis, and optic nerve anatomy. Also includes examination information, fundus images and visual field defects. Presenting Symptom: Proptosis; Hemianopsia; Scotoma. Anatomy: Optic nerve; Structure of pituitary fossa; Optic nerve sheath. Dise... | Optic Nerve; Structure of Pituitary Fossa; Optic Nerve Sheath; Proptosis; Hemianopsia; Scotoma; Optic Nerve Neoplasms; Meningioma; Optic Nerve Glioma; Chiasmal Visual Field Defects |
| 66 |
 |
Optic Neuritis Treatment Trials | Alfredo A. Sadun, MD, PhD | Anatomy: Optic nerve. Disease/Diagnosis: Optic neuritis; Multiple sclerosis. Treatment: Methylprednisolone; Prednisone; Solumedrol. | Optic Neuritis; Multiple Sclerosis; Optic Nerve; Methylprednisolone; Prednisone; Solumedrol |
| 67 |
 |
Optical Coherence Tomography (OCT) Applications in the Eye | Alfredo A. Sadun, MD, PhD | Optical Coherence Tomography is a technique for non-invasive cross-sectional imaging of ocular tissues. This PowerPoint covers an overview of the technique with excellent diagrams and images. Anatomy: Retina; Anterior eye segment; Cornea; Macula Lutea; Vitreous body; Optic nerve; Retinal ganglion ce... | Tomography, Optical Coherence; Retina; Anterior Eye Segment; Cornea; Macula Lutea; Vitreous Body; Optic Nerve; Retinal Ganglion Cells; Retinal Diseases; Glaucoma; Macular Edema; Retinal Edema; NFLA Optical Coherence Tomography |
| 68 |
 |
Pentoxifylline Suppression of TNF-Alpha Mediated Axonal Degeneration in the Rabbit Optic Nerve | Alfredo A. Sadun, MD, PhD | Presenting Symptom: Dyschromatopsia. Anatomy: Optic nerve. Disease/Diagnosis: Acquired Immunodeficiency Syndrome; Demyelinating autoimmune diseases, CNS. Treatment: Pentoxifylline. | Pentoxifylline; Optic Nerve; Acquired Immunodeficiency Syndrome; Demyelinating Autoimmune Diseases, CNS; Dyschromatopsia; Tumor Necrosis Factor-Alpha |
| 69 |
 |
Posterior Ischemic Optic Neuropathy | Alfredo A. Sadun, MD, PhD | Discusses opthalmic complications of surgery, with example of shock-induced Posterior Ischemic Optic Neuropathy following a hysterectomy. Presenting Symptom: Ischemia; Hypotension. Anatomy: Optic nerve. Disease/Diagnosis: Optic neuropathy, Ischemic; Hematoma; Edema. | Optic Neuropathy, Ischemic; Hematoma; Edema; Ischemia; Hypotension; Optic Nerve; Posterior Ischemic Optic Neuropathy |
| 70 |
 |
Preparing for the RRC | Alfredo A. Sadun, MD, PhD | Discussion of the work of the Residency Review Committee and how a department can prepare for their visit. | Opthalmology; Medical Education; Internship and Residency |
| 71 |
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The Process of Resident Selection | Alfredo A. Sadun, MD, PhD | Evaluation and selection of residency candidates. Includes a section on "Ophthalmology matching program" presented at AAO meeting in Anaheim, Nov. 2003, with permission of Doug Perry. | Opthalmology; Medical Education; Internship and Residency |
| 72 |
 |
Prognosis for Vision in Idiopathic Intracranial Hypertension (IIH) | Alfredo A. Sadun, MD, PhD | Treatment options for Pseudotumor cerebri and Papilledema; includes images of optic disc with edema. Presenting Symptom: Scotoma. Anatomy: Optic disc; Optic nerve. Pathology: Microscopic view of papilledema. Disease/Diagnosis: Pseudotumor cerebri; Papilledema. Treatment: Acetazolamide; Ventriculoper... | Optic Nerve; Optic Disc; Pseudotumor Cerebri; Papilledema; Scotoma; Acetazolamide; Ventriculoperitoneal Shunt; Lumbo-Peritoneal CSF Shunt; Decompression of Optic Nerve; Raised Intracranial Pressure |
| 73 |
 |
Program Director Collaboration Model: On Being a Program Director | Alfredo A. Sadun, MD, PhD | A slide presentation on the role of a project manager. | Opthalmology; Medical Education; Internship and Residency |
| 74 |
 |
Pupils and Fields: The Importance of Assessing the Optic Nerve | Alfredo A. Sadun, MD, PhD | Presenting Symptom: Anisocoria; Adie syndrome; Scotoma; Afferent pupillary defect; Horner Syndrome; Edema; Papilledema; Optic nerve; Pupil; Optic disc. Anatomy: Optic nerve; Pupil; Optic disc. Disease/Diagnosis: Afferent pupillary defect; Horner Syndrome; Edema; Papilledema. | Anisocoria; Adie Syndrome; Scotoma; Afferent Pupillary Defect; Horner Syndrome; Edema; Papilledema; Optic Nerve; Pupil; Optic Disc |
| 75 |
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Pupils and the Neuro-Ophthalmic Manifestations of Diabetes | Alfredo A. Sadun, MD, PhD | Presentation given in Italy on diagnosing neuro-opthalmic complications of diabetes with several views of the optic disc. Presenting symptom: Diplopia; Anisocoria; Ptosis; Horner syndrome; Adie syndrome. Anatomy: Pupil; Optic disc; Optic nerve. Disease/Diagnosis: Diabetes; Mucormycosis; Acidosis; Hy... | Pupil; Optic Disc; Optic Nerve; Diplopia; Anisocoria; Ptosis; Horner Syndrome; Adie Syndrome; Diabetes; Mucormycosis; Acidosis; Hypoplasia of the Optic Nerve; Diabetes Mellitus; Diabetic Optic Papillopathy; Optic Neuropathy, Ischemic; Diabetic Optic Atrophy; Ophthalmoplegia; Diabetic Ketoacidosis; D... |