The Alfredo A. Sadun Neuro-Ophthalmology Collection: A Professor of Ophthalmology and Neurological Surgery at the USC Keck School of Medicine, Dr. Sadun with a team of researchers at the Doheny Eye Institute pioneered research in optic nerve dysfunction in patients with Alzheimer's disease. Contains his "100 best lectures." Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor Ophthalmology & Neurological Surgery, Doheny Eye Institute, Keck School of Medicine at USC.
NOVEL: https://novel.utah.edu/
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| Title | Creator | Description | Subject | ||
|---|---|---|---|---|---|
| 26 |
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Cushing and Ophthalmology | Alfredo A. Sadun, MD, PhD | From a lecture at Yale in 2006, reviewing the life of Harvey Cushing, the founder of neurosurgery. Anatomy: Optic chiasm; Optic nerve. Disease/Diagnosis: Pituitary adenoma; Papilledema; X-linked hydrocephalus syndrome; Optic nerve glioma; Graves ophthalmopathy; Mucocele; Pituitary apoplexy; Optic ne... | Cushing, Harvey, 1869-1939; Neurosurgery; Optic Chiasm; Optic Nerve; Proptosis; Diplopia; Ptosis; Hemianopsia; Pituitary Adenoma; Papilledema; X-linked Hydrocephalus Syndrome; Optic Nerve Glioma; Graves Ophthalmopathy; Mucocele; Pituitary Apoplexy; Optic Nerve Atrophy; Neurosurgery; Decompression, S... |
| 27 |
 |
The Diagnostic Workup in Patients With Optic Neuropathies | Alfredo A. Sadun, MD, PhD | Slideshow presentation with images of optic disc with edema and optic atrophy. Presenting Symptom: Telangiectasis; Dyschromatopsia; Scotoma. Anatomy: Optic nerve; Optic disc; Phosphopyruvate Hydratase; Enolase. Disease/Diagnosis: Optic neuritis; Macular edema; Optic neuropathy, Ischemic; Optic atrop... | Telangiectasis; Dyschromatopsia; Scotoma; Optic Nerve; Optic Disc; Phosphopyruvate Hydratase; Enolase; Optic Neuritis; Macular Edema; Optic Neuropathy, Ischemic; Optic Atrophy, Hereditary |
| 28 |
 |
The Diagnostic Workup in Patients With Optic Neuropathies (Metodo diagnostico) | Alfredo A. Sadun, MD, PhD | Slideshow presentation with images of optic disc with edema and "Positive temporal artery biopsy". Presenting Symptom: Hyperopia; Metamorphopsia. Anatomy: Optic nerve; Macula Lutea; Optic disc. Disease/Diagnosis: Optic neuritis; Macular edema; Optic neuropathy, Ischemic. | Hyperopia; Metamorphopsia; Optic Nerve; Macula Lutea; Optic Disc; Optic Neuritis; Macular Edema; Optic Neuropathy, Ischemic |
| 29 |
 |
Distinguishing an Optic Neuropathy from a Maculopathy | Alfredo A. Sadun, MD, PhD | PPT describing a case of optic neuropathy. Covers signs and symptoms, and various laboratory tests. Describes 10 signes of disc edema. Anatomy: Optic nerve; Retina; Retinal macula. Disease/Diagnosis: Optic nerve diseases; Retinal lesion; Macular lesion; Disorder of the optic nerve; Afferent pupillar... | Optic Nerve Diseases; Retinal Lesion; Macular Lesion; Disorder of the Optic Nerve; Afferent Pupillary Defect; Edema; Optic Nerve; Retina; Retinal Macula; Scotoma; Optic Neuritis; Hyperopia; Metamorphopsia; Diseases of the Optic Nerve |
| 30 |
 |
Distinguishing Optic Nerve vs. Retinal Lesions | Alfredo A. Sadun, MD, PhD | PPT describing methods of distinguishing optic nerve verses retinal lesions. Describes a pateint case. Discussed signs, symtpoms and diagnostic tests. Anatomy: Optic nerve; Retina; Retinal macula. Disease/Diagnosis: Optic nerve diseases; Retinal lesion; Macular lesion; Disorder of the optic nerve; A... | Optic Nerve Diseases; Retinal Lesion; Disorder of the Optic Nerve; Macular Lesion; Retinal Macula; Afferent Pupillary Defect; Scotoma; Optic Neuritis; Hyperopia; Metamorphopsia; Optic Nerve; Retina; Diseases of the Optic Nerve |
| 31 |
 |
Engineering the Visual System | Alfredo A. Sadun, MD, PhD | Physiological basis of vision, covering perimetry, retinal ganglion cell types, and retinal pathways. Anatomy: Optic nerve; Retina. | Vision; Color Perception; Optic Nerve; Retina; Afferent Visual Pathways |
| 32 |
 |
The Expert Witness | Alfredo A. Sadun, MD, PhD | Discussion and advice on serving as an expert witness during court cases. | Expert Testimony |
| 33 |
 |
Extremely High Resolution Magnetic Resonance Imaging of the Human Optic Nerve Head | Alfredo A. Sadun, MD, PhD | MRI imagery of optic nerves demonstrates ability to identify cases of Leber's Hereditary Optic Neuropathy (LHON); includes MRI images of optic nerves. Anatomy: Optic nerve. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. | Optic Nerve; Optic Atrophy, Hereditary, Leber; Magnetic Resonance Imaging |
| 34 |
 |
Field Investigation of a Giant Pedigree of LHON in Rural Brazil | Alfredo A. Sadun, MD, PhD | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis. Anatomy: Optic nerve; Optic disk. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Blindness, | Optic Atrophy; Hereditary; Leber; Blindness; Brazil; Optic Nerve; Optic Disc |
| 35 |
 |
Headache | Alfredo A. Sadun, MD, PhD | Presenting Symptom: Ataxia; Photophobia; Scotoma; Ischemia; Aura. Anatomy: Orbit; Retina; Serotonin. Disease/Diagnosis: Migraine disorders; Migraine with aura. Treatment: Ibuprofen; Sumatriptan; Pseudoephedrine; Lidocaine; Caffeine; Calcium channel blockers; Aminosalicylic acids. | Migraine Disorders; Migraine With Aura; Aura; Ataxia; Photophobia; Scotoma; Ischemia; Orbit; Retina; Serotonin; Ibuprofen; Sumatriptan; Pseudoephedrine; Lidocaine; Caffeine; Calcium Channel Blockers; Aminosalicylic Acids; Headache and Facial Pain |
| 36 |
 |
Headache and Visual Loss | Alfredo A. Sadun, MD, PhD | Presenting Symptom: Ataxia; Photophobia; Scotoma; Ischemia; Aura. Anatomy: Orbit; Retina; Serotonin. Disease/Diagnosis: Migraine disorders; Migraine with aura. Imaging: Ibuprofen; Sumatriptan; Pseudoephedrine; Lidocaine; Caffeine; Calcium channel blockers; Aminosalicylic acids. | Ataxia; Photophobia; Scotoma; Ischemia; Aura; Migraine Disorders; Migraine With Aura; Ibuprofen; Sumatriptan; Pseudoephedrine; Lidocaine; Caffeine; Calcium Channel Blockers; Aminosalicylic Acids; Orbit; Retina; Serotonin |
| 37 |
 |
How Mitochondria Orchestrate the Death of RGCs : From Brazil to Tuebingen to Rochester 2007 | Alfredo A. Sadun, MD, PhD | Slides showing LHON and Kjer's optic atrophy and images of optic disk with LHON. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia; Blindness. | Optic Nerve; Retina; Retinal Ganglion Cells; Reactive Oxygen Species; Scotoma; Telangiectasis; Apoptosis; Cell Death; Dyschromatopsia; Blindness; Optic Atrophy; Hereditary; Leber; Leber's Optic Neuropathy |
| 38 |
 |
How Strong is the Case for an Association Between PDE5 Inhibitors and NAION? | Alfredo A. Sadun, MD, PhD | Anatomy: Optic nerve. Disease/Diagnosis: Optic Neuropathy, Ischemic; Toxic optic neuropathy. Presenting Symptom: Ischemia; Scotoma; Dyschromatopsia. | Optic Neuropathy, Ischemic; Toxic Optic Neuropathy; Ischemia; Scotoma; Dyschromatopsia; Optic Nerve; Phosphodiesterase 5 Inhibitor; Viagra |
| 39 |
 |
Induction of Apoptosis by Mitochondrial Impairment in LHON and Related Diseases | Alfredo A. Sadun, MD, PhD | Slide presentation includes six pairs of microscopic slides showing LHON and control examples of optic nerve. Anatomy: Optic nerve. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. | Optic Atrophy, Hereditary, Leber; Apoptosis; Cell Death |
| 40 |
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Jonathan D. Wirtschafter, MD, FACS, Frank E. Burch Professor of Ophthalmology | Alfredo A. Sadun, MD, PhD | Overview of the life of Jonathan D. Wirtschafter on the occasion of the first annual Wirtschafter Lectureship, in August of 2003. Sadun gave the lecture, recapping an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis. Includes several images o... | Optic Atrophy, Hereditary, Leber; Blindness; Scotoma; Dyschromatopsia; Brazil; Optic Nerve; Optic Disk; Apoptosis; Cell Death; Wirtschafer, Jonathan D. |
| 41 |
 |
Leber's Hereditary Optic Neuropathy (LHON) in Brazil: Opportunities | Alfredo A. Sadun, MD, PhD | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic roots. Presented at Allergan, 2006. Includes several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Myelin sheath; Optic Disk. Disease/Diagnosis: Optic Atrophy, H... | Optic Atrophy, Hereditary, Leber; Optic Nerve; Optic Disk; Myelin Sheath; Brimonidine; Alphagan; Edema; Scotoma; Telangiectasis; Blindness; Brazil |
| 42 |
 |
Leber's Hereditary Optic Neuropathy (LHON): New Rules of Engagement | Alfredo A. Sadun, MD, PhD | Slide presentation with several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Blindness. | Optic Atrophy; Hereditary; Leber; Apoptosis; Cell Death; Blindness; Brazil; Optic Nerve; Optic Disk; Retinal Ganglion Cells; Reactive Oxygen Species |
| 43 |
 |
Leber's Hereditary Optic Neuropathy: A Very Large New Pedigree From Brazil | Alfredo A. Sadun, MD, PhD | Four slides showing optic disc with LHON. Anatomy: Optic nerve; Optic disk. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Blindness. | Optic Atrophy; Hereditary; Leber; Blindness; Brazil; Optic Nerve; Optic Disc |
| 44 |
 |
Leber's Hereditary Optic Neuropathy: A Very Large New Pedigree in Brazil | Alfredo A. Sadun, MD, PhD | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis. Includes several images of optic nerve and optic disk with LHON, Anatomy: Optic nerve; Optic disk; Retinal ganglion cells. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Pres... | Optic Atrophy; Hereditary; Leber; Blindness; Scotoma; Dyschromatopsia; Brazil; Optic Nerve; Optic Disk; Retinal Ganglion Cells; Apoptosis; Cell Death |
| 45 |
 |
Leber's Hereditary Optic Neuropathy: A Very Large New Pedigree in Brazil | Alfredo A. Sadun, MD, PhD | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis. Includes several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Optic disk. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Blindnes... | Optic Atrophy, Hereditary, Leber; Blindness; Brazil; Optic Nerve; Optic Disc |
| 46 |
 |
Leber's Hereditary Optic Neuropathy: New Insights? | Alfredo A. Sadun, MD, PhD | Several microscopic images of optic nerve with LHON. Anatomy: Optic nerve. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Scotoma; Dyschromatopsia. | Optic Atrophy, Hereditary, Leber; Optic nerve; Scotoma; Dyschromatopsia |
| 47 |
 |
Leber's Hereditary Optic Neuropathy: New Lessons From a Giant Pedigree in Brazil | Alfredo A. Sadun, MD, PhD | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis; includes several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Pres... | Optic Atrophy, Hereditary, Leber; Blindness; Papilledema; Scotoma; Dyschromatopsia; Optic Nerve; Optic Disc; Retinal Ganglion Cells; Brazil; Apoptosis; Cell Death |
| 48 |
 |
Management Approach to Isolated Ocular Motor Nerve Palsies | Alfredo A. Sadun, MD, PhD | Anatomy: Optic nerve; Oculomotor nerve; Trochlear nerve; Abducens nerve; Pupil. Disease/Diagnosis: Oculomotor nerve diseases; Trochlear nerve diseases; Oculomotor nerve paralysis; Fourth cranial nerve palsy; Abducens nerve diseases; Gradenigo's syndrome; Ophthalmoplegia; Temporal Arteritis; Nerve co... | Diplopia; Hypertropia; Optic Nerve; Oculomotor Nerve; Trochlear Nerve; Pupil; Oculomotor Nerve Diseases; Trochlear Nerve Diseases; Abducens Nerve; Abducens Nerve Diseases; Gradenigo's Syndrome; Ophthalmoplegia; Temporal Arteritis; Nerve Compression Syndromes |
| 49 |
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Medical-Legal Considerations: What You Wish You Didn't Have to Think About | Alfredo A. Sadun, MD, PhD | A slide presentation on the medico-legal issues relevant to neuro-ophthalmologists. | Liability, Legal; Medico-Legal Proceedings |
| 50 |
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Methods of Resident Evaluation: The 360 Degree Evaluation | Alfredo A. Sadun, MD, PhD | Evaluation of medical residents by faculty, hospital staff, peers, and patients. | Opthalmology; Medical Education; Internship and Residency |