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Title | Creator | Description | Subject | Imaging |
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Compressive Optic Neuropathies Potpourri | Alfredo A. Sadun, MD, PhD | An overview of compressive optic neuropathies, including symptoms, varieties, testing, and treatments; slide presentation includes several neuroimaging scans. Anatomy: Optic nerve. Disease/Diagnosis: Compression of optic nerve. Treatment: Mifepristone | Optic Nerve; Compression of Optic Nerve; Mifepristone | |
2 |
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Testing the Functional Patient | Alfredo A. Sadun, MD, PhD | Discusses testing to distinguish organic ailments from psychosomatic or willful simulation of symptoms. Anatomy: Optic nerve; Retina. Disease/Diagnosis: Optic nerve diseases; Retinal degeneration; Hysteria | Malingering; Hysteria; Optic Nerve; Retina; Optic Nerve Diseases; Retinal Degeneration | |
3 |
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Optic Nerve Tumors: Diagnosis and Therapy | Alfredo A. Sadun, MD, PhD | Powerppoint lecture covers a patient case, differential diagnosis, and optic nerve anatomy. Also includes examination information, fundus images and visual field defects. Presenting Symptom: Proptosis; Hemianopsia; Scotoma. Anatomy: Optic nerve; Structure of pituitary fossa; Optic nerve sheath. Dise... | Optic Nerve; Structure of Pituitary Fossa; Optic Nerve Sheath; Proptosis; Hemianopsia; Scotoma; Optic Nerve Neoplasms; Meningioma; Optic Nerve Glioma; Chiasmal Visual Field Defects | |
4 |
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Anatomy and Physiology of the Optic Nerve | Alfredo A. Sadun, MD, PhD | Lecture covering the anatomy and physiology of the optic nerve. Covers the retina and anterior visual pathways. Several slides show microscopic images of optic nerve damage. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Cytokines. Disease/Diagnosis: Glaucoma. | Optic Nerve; Retina; Retinal Ganglion Cells; Cytokines; Apoptosis; Cell Death; Glaucoma; Anatomy of the Optic Nerve; AVP Optic Nerve | |
5 |
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Distinguishing Optic Nerve vs. Retinal Lesions | Alfredo A. Sadun, MD, PhD | PPT describing methods of distinguishing optic nerve verses retinal lesions. Describes a pateint case. Discussed signs, symtpoms and diagnostic tests. Anatomy: Optic nerve; Retina; Retinal macula. Disease/Diagnosis: Optic nerve diseases; Retinal lesion; Macular lesion; Disorder of the optic nerve; A... | Optic Nerve Diseases; Retinal Lesion; Disorder of the Optic Nerve; Macular Lesion; Retinal Macula; Afferent Pupillary Defect; Scotoma; Optic Neuritis; Hyperopia; Metamorphopsia; Optic Nerve; Retina; Diseases of the Optic Nerve | |
6 |
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Distinguishing an Optic Neuropathy from a Maculopathy | Alfredo A. Sadun, MD, PhD | PPT describing a case of optic neuropathy. Covers signs and symptoms, and various laboratory tests. Describes 10 signes of disc edema. Anatomy: Optic nerve; Retina; Retinal macula. Disease/Diagnosis: Optic nerve diseases; Retinal lesion; Macular lesion; Disorder of the optic nerve; Afferent pupillar... | Optic Nerve Diseases; Retinal Lesion; Macular Lesion; Disorder of the Optic Nerve; Afferent Pupillary Defect; Edema; Optic Nerve; Retina; Retinal Macula; Scotoma; Optic Neuritis; Hyperopia; Metamorphopsia; Diseases of the Optic Nerve | |
7 |
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An Epidemic of Blindness in Cuba: Lessons on Nutrition and Mitochondria | Alfredo A. Sadun, MD, PhD | Presented at Stanford in April 2007, recapping the 1990s expedition to Cuba to investigate causes of blindness epidemic. Anatomy: Optic nerve. Disease/Diagnosis: Optic nerve diseases; Alcoholic neuropathy. Treatment: Folate. Presenting Symptom: Ambliopia; Ataxia; Paresthesia; Hyporeflexia. | Cuba; Castro, Fidel; Folate; Optic Nerve; Optic Nerve Diseases; Alcoholic Neuropathy; Blindness; Ambliopia; Ataxia; Paresthesia; Hyporeflexia | |
8 |
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Cuban Epidemic of Optic Neuropathy: Even Zealots Must Eat, or, Conversations with Castro | Alfredo A. Sadun, MD, PhD | A team of neuro-opthalmologists visits Cuba in 1993 and 1994, and attempts to treat patients with vision disorders. Anatomy: Optic nerve. Disease/Diagnosis: Optic nerve diseases; Alcoholic neuropathy. Treatment: Folate. Presenting Symptom: Blindness; Ambliopia; Ataxia; Paresthesia; Hyporeflexia. | Cuba; Castro, Fidel; Folate; Optic Nerve; Optic Nerve Diseases; Blindness; Ambliopia; Alcoholic Neuropathy; Ataxia; Paresthesia; Hyporeflexia | |
9 |
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Visual Fields | Alfredo A. Sadun, MD, PhD | Slideshow presentation with images of bow-tie atrophy due to an optic disc tract lesion. Anatomy: Optic chiasm; Optic nerve; Optic disk. Disease/Diagnosis: Pituitary adenoma; Bitemporal hemianopia; Optic nerve atrophy. | Visual Fields; Amsler Chart; Optic Chiasm; Optic Nerve; Optic Disk; Pituitary Adenoma; Bitemporal Hemianopia; Optic Nerve Atrophy | |
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Leber's Hereditary Optic Neuropathy: New Insights? | Alfredo A. Sadun, MD, PhD | Several microscopic images of optic nerve with LHON. Anatomy: Optic nerve. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Scotoma; Dyschromatopsia. | Optic Atrophy, Hereditary, Leber; Optic nerve; Scotoma; Dyschromatopsia | |
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Cuban Epidemic of Optic Neuropathy: Even Zealots Must Eat, or, Conversations with Castro | Alfredo A. Sadun, MD, PhD | A team of neuro-opthalmologists visits Cuba in 1993 and 1994, and attempts to treat patients with vision disorders. Anatomy: Optic nerve; Structure of cribriform plate. Disease/Diagnosis: Optic nerve diseases; Blindness; Ambliopia; Alcoholic neuropathy. Treatment: Folate. Presenting Symptom: Ataxia;... | Cuba; Castro, Fidel; Folate; Optic Nerve; Structure of Cribriform Plate; Optic Nerve Diseases; Alcoholic Neuropathy; Blindness; Ambliopia; Ataxia; Paresthesia; Hyporeflexia | |
12 |
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Engineering the Visual System | Alfredo A. Sadun, MD, PhD | Physiological basis of vision, covering perimetry, retinal ganglion cell types, and retinal pathways. Anatomy: Optic nerve; Retina. | Vision; Color Perception; Optic Nerve; Retina; Afferent Visual Pathways | |
13 |
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Extremely High Resolution Magnetic Resonance Imaging of the Human Optic Nerve Head | Alfredo A. Sadun, MD, PhD | MRI imagery of optic nerves demonstrates ability to identify cases of Leber's Hereditary Optic Neuropathy (LHON); includes MRI images of optic nerves. Anatomy: Optic nerve. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. | Optic Nerve; Optic Atrophy, Hereditary, Leber; Magnetic Resonance Imaging | |
14 |
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Optic Neuritis Treatment Trials | Alfredo A. Sadun, MD, PhD | Anatomy: Optic nerve. Disease/Diagnosis: Optic neuritis; Multiple sclerosis. Treatment: Methylprednisolone; Prednisone; Solumedrol. | Optic Neuritis; Multiple Sclerosis; Optic Nerve; Methylprednisolone; Prednisone; Solumedrol | |
15 |
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Prognosis for Vision in Idiopathic Intracranial Hypertension (IIH) | Alfredo A. Sadun, MD, PhD | Treatment options for Pseudotumor cerebri and Papilledema; includes images of optic disc with edema. Presenting Symptom: Scotoma. Anatomy: Optic disc; Optic nerve. Pathology: Microscopic view of papilledema. Disease/Diagnosis: Pseudotumor cerebri; Papilledema. Treatment: Acetazolamide; Ventriculoper... | Optic Nerve; Optic Disc; Pseudotumor Cerebri; Papilledema; Scotoma; Acetazolamide; Ventriculoperitoneal Shunt; Lumbo-Peritoneal CSF Shunt; Decompression of Optic Nerve; Raised Intracranial Pressure | |
16 |
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Field Investigation of a Giant Pedigree of LHON in Rural Brazil | Alfredo A. Sadun, MD, PhD | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis. Anatomy: Optic nerve; Optic disk. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Blindness, | Optic Atrophy; Hereditary; Leber; Blindness; Brazil; Optic Nerve; Optic Disc | |
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Leber's Hereditary Optic Neuropathy: A Very Large New Pedigree From Brazil | Alfredo A. Sadun, MD, PhD | Four slides showing optic disc with LHON. Anatomy: Optic nerve; Optic disk. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Blindness. | Optic Atrophy; Hereditary; Leber; Blindness; Brazil; Optic Nerve; Optic Disc | |
18 |
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Leber's Hereditary Optic Neuropathy: A Very Large New Pedigree in Brazil | Alfredo A. Sadun, MD, PhD | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis. Includes several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Optic disk. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Blindnes... | Optic Atrophy, Hereditary, Leber; Blindness; Brazil; Optic Nerve; Optic Disc | |
19 |
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Mitochondrial Optic Neuropathy: Mitochondria as Gatekeepers for Apoptosis | Alfredo A. Sadun, MD, PhD | Presentation at Harvard in 2006, focussing on Leber's Heriditary Optic Neuropathy; includes several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells. Disease/Diagnosis: Optic nerve diseases; Optic Atrophy, Hereditary, Leber. Presenting Symptom:... | Scotoma; Dyschromatopsia; Ataxia; Hyporeflexia; Optic Nerve Diseases; Optic Atrophy, Hereditary, Leber; Cuba; Brazil; Optic Nerve; Optic Disk; Retinal Ganglion Cells; Apoptosis; Cell Death; Ethambutol | |
20 |
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Cushing and Ophthalmology | Alfredo A. Sadun, MD, PhD | From a lecture at Yale in 2006, reviewing the life of Harvey Cushing, the founder of neurosurgery. Anatomy: Optic chiasm; Optic nerve. Disease/Diagnosis: Pituitary adenoma; Papilledema; X-linked hydrocephalus syndrome; Optic nerve glioma; Graves ophthalmopathy; Mucocele; Pituitary apoplexy; Optic ne... | Cushing, Harvey, 1869-1939; Neurosurgery; Optic Chiasm; Optic Nerve; Proptosis; Diplopia; Ptosis; Hemianopsia; Pituitary Adenoma; Papilledema; X-linked Hydrocephalus Syndrome; Optic Nerve Glioma; Graves Ophthalmopathy; Mucocele; Pituitary Apoplexy; Optic Nerve Atrophy; Neurosurgery; Decompression, S... | |
21 |
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Apoptosis of Retinal Ganglion Cells | Alfredo A. Sadun, MD, PhD | Presented at a conference on neuroprotection at Sedona, Arizona, 2002; includes several microscopic images demonstrating cell death. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Cytokines. Disease/Diagnosis: Glaucoma. | Optic Nerve; Retina; Retinal Ganglion Cells; Cytokines; Apoptosis; Cell Death; Glaucoma | |
22 |
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Neuro-Surgical Approaches to the Orbit | Alfredo A. Sadun, MD, PhD | Discusses specifics of various approaches to surgical treatment of lesions, including transcranial and transfrontal orbitotomies; neuroimagery scans from before and after operation for meningioma. Presenting Symptom: Proptosis. Anatomy: Orbit; Optic nerve sheath. Disease/Diagnosis: Meningioma; Heman... | Coloboma; Aplasia; Proptosis; Orbit; Optic Nerve Sheath; Meningioma; Hemangiopericytoma; Neurosurgery; Osteotomy | |
23 |
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Mitochondrial Optic Neuropathies (MON) | Alfredo A. Sadun, MD, PhD | Combination of two presentations on optic nerve diseases, covering the cases in Cuba and Brazil. Titles: Cuban epidemic of optic neuopathy: even zealots must eat, or, Conversations with Castro and Leber's hereditary optic neuropathy: a very large new pedigree in Brazil; includes several images of ... | Optic Nerve Diseases; Optic Atrophy, Hereditary, Leber; Blindness; Alcoholic Neuropathy; Cuba; Castro, Fidel; Folate; Brazil; Optic Nerve; Optic Disk; Retinal Ganglion Cells; Apoptosis; Cell Death | |
24 |
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Optic Nerve Sheath Decompression in the Management of Optic Neuropathies | Alfredo A. Sadun, MD, PhD | A slide presentation with several images of optic disc, normal and with edema. Anatomy: Optic nerve; Optic disc. Disease/Diagnosis: Optic neuropathy, Ischemic; Pseudotumor cerebri; Papilledema. Treatment: Decompression, Surgical. | Decompression, Surgical; Optic Neuropathy, Ischemic; Pseudotumor Cerebri; Papilledema; Optic Nerve; Optic Disc | |
25 |
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Acute Retrobulbar Optical Neuropathy | Alfredo A. Sadun, MD, PhD | PPT covering acute retrobulbar optic neuropathy, including ischemic, inflammatory, anterior ischemic optic neuropathy (AION) and non-arteritic anterior ischemic optic neuropathy (NAION); includes brainscan images for optic neuritis and multiple sclerosis; optic disk with LHON and PION. Anatomy: Opt... | Optic Neuropathy, Ischemic; Giant Cell Arteritis; Edema; Multiple Sclerosis; Optic Atrophy, Hereditary, Leber; Ischemia; Hypotension; Edema; Optic Neuritis; Optic Nerve; Interferon-Beta-1a; Diseases of the Optic Nerve | |