The Alfredo A. Sadun Neuro-Ophthalmology Collection: A Professor of Ophthalmology and Neurological Surgery at the USC Keck School of Medicine, Dr. Sadun with a team of researchers at the Doheny Eye Institute pioneered research in optic nerve dysfunction in patients with Alzheimer's disease. Contains his "100 best lectures." Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor Ophthalmology & Neurological Surgery, Doheny Eye Institute, Keck School of Medicine at USC.
NOVEL: https://novel.utah.edu/
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Apoptosis in LHON: An ROS Explanation | A slide presentation describing apoptosis in LHON; includes several images of optic nerve and optic disk. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. | Text |
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Atypical Optic Neuropathies | A discussion of atypical optic neuropathies. Anatomy: Optic nerve; Optic disc. Pathology: Slides showing LHON. Disease/Diagnosis: Optic neuropathy, Ischemic; Optic atrophy, Hereditary, Leber; Toxic optic neuropathy. Presenting Symptom: Optic neuritis; Eye hemorrhage; Retinal vasculitis; Dyschromatop... | Text |
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Field Investigation of a Giant Pedigree of LHON in Rural Brazil | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis. Anatomy: Optic nerve; Optic disk. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Blindness, | Text |
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Jonathan D. Wirtschafter, MD, FACS, Frank E. Burch Professor of Ophthalmology | Overview of the life of Jonathan D. Wirtschafter on the occasion of the first annual Wirtschafter Lectureship, in August of 2003. Sadun gave the lecture, recapping an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis. Includes several images o... | Text |
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Leber's Hereditary Optic Neuropathy (LHON) in Brazil: Opportunities | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic roots. Presented at Allergan, 2006. Includes several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Myelin sheath; Optic Disk. Disease/Diagnosis: Optic Atrophy, H... | Text |
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Leber's Hereditary Optic Neuropathy (LHON): New Rules of Engagement | Slide presentation with several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Blindness. | Text |
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Leber's Hereditary Optic Neuropathy: A Very Large New Pedigree From Brazil | Four slides showing optic disc with LHON. Anatomy: Optic nerve; Optic disk. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Blindness. | Text |
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Leber's Hereditary Optic Neuropathy: A Very Large New Pedigree in Brazil | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis. Includes several images of optic nerve and optic disk with LHON, Anatomy: Optic nerve; Optic disk; Retinal ganglion cells. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Pres... | Text |
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Leber's Hereditary Optic Neuropathy: A Very Large New Pedigree in Brazil | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis. Includes several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Optic disk. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Blindnes... | Text |
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Leber's Hereditary Optic Neuropathy: New Lessons From a Giant Pedigree in Brazil | Report of an international field investigation to rural Brazil to study a cluster of LHON, including its genetic basis; includes several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Pres... | Text |
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Mitochondria and the RGC | Discussion of various forms of mitrochondrial optic neuropathies and how to distinguish from toxic optic neuropathies, with examples from Cuba and Brazil. Presenting Symptom: Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia. Anatomy: Optic nerve; Optic disc; Retinal ganglion cells; Reactive oxyge... | Text |
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Mitochondrial Optic Neuropathies (MON) | Combination of two presentations on optic nerve diseases, covering the cases in Cuba and Brazil. Titles: Cuban epidemic of optic neuopathy: even zealots must eat, or, Conversations with Castro and Leber's hereditary optic neuropathy: a very large new pedigree in Brazil; includes several images of ... | Text |
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Mitochondrial Optic Neuropathy: Mitochondria as Gatekeepers for Apoptosis | Presentation at Harvard in 2006, focussing on Leber's Heriditary Optic Neuropathy; includes several images of optic nerve and optic disk with LHON. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells. Disease/Diagnosis: Optic nerve diseases; Optic Atrophy, Hereditary, Leber. Presenting Symptom:... | Text |
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Subclinical Visual Abnormalities in Carriers With 11778 LHON from a 300 Member Brazilian Pedigree | Report of a multi-year international field investigation to rural Brazil to study a cluster of LHON, including its genetic roots. Presenting Symptom: Scotoma; Telangiectasis; Blindness. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells; Reactive oxygen species. Pathology: Slides showing LHON ... | Text |
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Toxic Optic Neuropathies: Mitochondria and the RGC | Discussion of various forms of mitrochondrial optic neuropathies and how to distinguish from toxic optic neuropathies, with examples from Cuba and Brazil; includes images of optic disc showing LHON. Presenting Symptom: Blindness; Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia. Anatomy: Optic ne... | Text |
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