Theses & Dissertations
 
Filters: Department: "Medicinal Chemistry" Collection: "ir_etd"
1 - 25 of 24
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AuthorTitleSubjectDatePublication Type
1 Sadat Hayatshahi, Sayyed HamedThe effect of atomistic interactions on RNA conformational distributions, folding and ligand binding via molecular dynamics simulations and docking2016dissertation
2 Richardson, Adam DavidChemical and biological studies of secondary metabolites from Lissoclinum patellaSea Squits; Physiology; Marine Metabolites2003-08dissertation
3 Thorson, Megan KathleenNovel hydrogen sulfide detection methods and their biological and industrial application2014-12dissertation
4 Hyde, Robyn MarieSenseless nucleic acid macromolecules: synthesis, charatcerization and biological studiesPhysiology; Metabolism; Analysis2002-05dissertation
5 Green, Brad ReedEngineering systemically bioavailable analogs of endogenous neuropeptidesNeurosciences; Biochemistry; Pharmacy sciences2010-12thesis
6 Stolk, Jacob AbrahamIn vivo 31p NMR as a noninvasive tool to study rodent cerebral metabolism as a function of ageMagnetic Resonance Spectroscopy; Rats1990-03dissertation
7 Cang, XiaohuiMolecular dynamics simulations on G-quadruplexesAMBER; DNA; Glycosidic conformation; G-quadruplex; Molecular dynamics; Structural polymorphism2010-12dissertation
8 Robertson, Charles RayPeptide-based therapeutics: engineering galanin for systemic anticonvulsant and anagesic activity2012-05dissertation
9 Li, HaoHyaluronan based biomaterial for antiadhesion and thermosensitive hyaluronan lanthanide complexesBiosynthesis; Mitomycin C2003-08thesis
10 Cornillie, Sean PaulBiomolecular simulation protocols enabling effective peptide therapeutic design: model validation and optimizationPublic health; Physiology; Epidemiology; Biophysics2018dissertation
11 Sha, JiangDesign, synthesis and evaluation of doxorubicin based anti-cancer drug conjugatesPharmacology2006-08thesis
12 Zabriskie, T. MarkThe Characterization of cytotoxic metabolites from Fijian marine invertebratesPeptides, Cyclic; Porifera; Thiazoles; Urochordata1989-12dissertation
13 Donia, Mohamed Samir AbouBiosynthesis and genetic engineering of biologically active natural products from marine ascidian symbionts2010-08dissertation
14 dela Cruz, Richard Glenn CuaAntithrombin III residue tyrosine-131 serves as a molecular switch during heparinmediated conformational activation of its anticoagulant activityPentasaccharide; Allosteric Activation; Mutants2006-05dissertation
15 Mullally, James EdwardDiscovery of novel effectors of the proteasome pathway: cyclopentenones as inhibitors of ubiquitin isopeptidase activityNeoplasms; Drug Therapy2003-05dissertation
16 McKee, Tawnya CarleneBioactive metabolites from marine organisms: the chemistry of Xestospongia Caycedoi, Diplosoma species Trididemnum solidum and the marine microbe Streptomyces speciesMicrobial Metabolites; Biochemistry1990-12dissertation
17 Sundaram, MallikarjunEffect of modified nucleosides on the structure of the anticodon domain of Escherichia coli tRNALysEscherichia coli; tRNA(Lys), Nucleosides, Anticodon domain; Biochemistry2000-08dissertation
18 Paulsen, Ryan B.Solution structure of a benzimidazole inhibitor in complex with domain iIA of the hepatitis C virus internal ribosome entry site2010-12dissertation
19 Bhalgat, Mahesh KantilalAntibody-directed delivery of copper-67 to tumorsMonoclonal Antibodies; Raiommunoconjugates1995-06dissertation
20 Champine, Patricia J.Investigating the biological response to reduction of methyl-CpG-binding domain protein 2 in colon cancerEtiology2003-08thesis
21 Pomerantz, Steven C.Characterization of complex mixtures of isomeric oligonucleotides by electrospray ionization tendem mass spectrometryElectron Ionization; Tetramethylethylenediamine2002-08dissertation
22 Kakule, Thomas ButanazibaEngineering combinatorial biosynthesis of polyketide synthase-pepide synthetase products using novel fungal genetic toolsGenetics; Biochemistry2015-05dissertation
23 Brown, Spencer JuddMethods for the production of heparan sulfate structure libraries and their applications2020dissertation
24 Smith, Thomas E.Integrated approaches for the discovery and production of marine natural productsChemistry; Biochemistry; Bioinformatics2016-12dissertation
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