Theses & Dissertations
 
Filters: Department: "Medicinal Chemistry" Collection: "ir_etd"
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AuthorTitleSubjectDatePublication Type
1 Van Wagoner, Ryan MichaelStructural studies on the psi-conotoxins and the secondary metabolites of a marine tunicateDeoxyribonucleic Acid; Tetrahydropentoxoyline2001-08dissertation
2 Steiner, Andrew M.Oxidative folding of conotoxins: chemical and biological developments to efficiency of production of short, cysteine-rich peptides2013-05dissertation
3 Cornillie, Sean PaulBiomolecular simulation protocols enabling effective peptide therapeutic design: model validation and optimizationPublic health; Physiology; Epidemiology; Biophysics2018dissertation
4 Francom, PaulaNonclassical folate analogs as inhibitors of dihydrofolate reductase and thymidylate synthaseTherapeutic Use; Organic Chemistry1996-08dissertation
5 Green, Brad ReedEngineering systemically bioavailable analogs of endogenous neuropeptidesNeurosciences; Biochemistry; Pharmacy sciences2010-12thesis
6 Bugni, Timothy ScottInvestigation of marine-derived fungi for bioactive natural productsAspergillus niger; Aplidium; Pencillium brocae. Yanuthones2003-08dissertation
7 Richardson, Adam DavidChemical and biological studies of secondary metabolites from Lissoclinum patellaSea Squits; Physiology; Marine Metabolites2003-08dissertation
8 Deshmukh, Hemant M.Synthesis and characterization of oligonucleotides containing 2'-0-substitued adenosinesRNA Hybarids; NMR Studies1994-08dissertation
9 Fernandez, Annette M.Isolation and characterization of vitilevuamide from the ascidians Didemnum cuculliferum and Polysyncraton lithostrotumAntineoplastic Agents; Pharmacognosy1996-12dissertation
10 Bhalgat, Mahesh KantilalAntibody-directed delivery of copper-67 to tumorsMonoclonal Antibodies; Raiommunoconjugates1995-06dissertation
11 Mitchell, Scott S.Structural investigations of metabolites from four marine invertebratesAscidian Didemnum Voeltzkowi; Conotoxin; Amphimedon Viridis1997-08dissertation
12 Zabriskie, T. MarkThe Characterization of cytotoxic metabolites from Fijian marine invertebratesPeptides, Cyclic; Porifera; Thiazoles; Urochordata1989-12dissertation
13 Sundaram, MallikarjunEffect of modified nucleosides on the structure of the anticodon domain of Escherichia coli tRNALysEscherichia coli; tRNA(Lys), Nucleosides, Anticodon domain; Biochemistry2000-08dissertation
14 Feng, LiProbing phosphoinositide and isoprenoid binding proteins by photoaffinity labelingBiochemistry; N,N-dimethylformamide1999-12dissertation
15 Joglekar, Seema P.Triplex-forming branched obligonucleotides: sythesis and interactions with ribo- and deoxyribo-oligonucleotidesDeosyribo-oligonucleotides; Ribo-olgonucleotides; Triplex2001-05dissertation
16 Sardar, DebosmitaThe cyanobactin biosynthetic machinery: promiscuity, modularity and unique chemistry from the oceansBiochemistry2016dissertation
17 McIntosh, John AndrewElucidation of cyanobactin biosynthesisBiochemistry2011-12dissertation
18 Cai, ShenshenGlycosaminoglycans and their binding proteins: biochemical studies and development of potential wound healing biomaterials2005-12dissertation
19 McKee, Tawnya CarleneBioactive metabolites from marine organisms: the chemistry of Xestospongia Caycedoi, Diplosoma species Trididemnum solidum and the marine microbe Streptomyces speciesMicrobial Metabolites; Biochemistry1990-12dissertation
20 Cheng, Chin Shu.Studies on the synthesis and biological evaluation of certain pyrrolo[2,3-d] pyrimidine nucleosides and their methylated analogs which are structurally related to the naturally occurring nucleoside Q, nucleoside Q*, and methylated guanosines.RNA; Cytotoxicity1981-06dissertation
21 Bi, YilingApplications of computational tools and biochemical approaches in elucidating biogenesis of antithrombin III bibduing heparan sulfate structures, defining xyloside-mediated glycosaminoglycan priming activity, and discovering drugs to treat human n-glycanase 1 (NGLYI) deficiency2019dissertation
22 Cline, Barry LeeSynthesis of certain imidazo [4, 5-b] pyridine (1-deazapurine) and v-triazolo [4,5-b] pyridine (1-deaza-8-azapurine) nucleosides related to guanosine1976-12dissertation
23 Sadat Hayatshahi, Sayyed HamedThe effect of atomistic interactions on RNA conformational distributions, folding and ligand binding via molecular dynamics simulations and docking2016dissertation
24 Donia, Mohamed Samir AbouBiosynthesis and genetic engineering of biologically active natural products from marine ascidian symbionts2010-08dissertation
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