Theses & Dissertations
 
Filters: Department: "Medicinal Chemistry" Collection: "ir_etd"
1 - 25 of 21
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AuthorTitleSubjectDatePublication Type
1 Bi, YilingApplications of computational tools and biochemical approaches in elucidating biogenesis of antithrombin III bibduing heparan sulfate structures, defining xyloside-mediated glycosaminoglycan priming activity, and discovering drugs to treat human n-glycanase 1 (NGLYI) deficiency2019dissertation
2 Cornillie, Sean PaulBiomolecular simulation protocols enabling effective peptide therapeutic design: model validation and optimizationPublic health; Physiology; Epidemiology; Biophysics2018dissertation
3 Veltri, Charles AnthonyIdentification of cellular targets of marine natural productsNatural Products; Marine Pharmacology2010-04-21dissertation
4 Booth, Randy AlanNovel phosphoinositide-protein interactions and inhibition of Akt activationSignal Transduction; Peptides; Protein Kinases2004-05dissertation
5 Smith, Diana K.Structures of the Klebsiella oxytoca phage Phi KO2 and vibrio harveyi myovirus-like protelomerase far C-terminal domains2010-08dissertation
6 Tianero, Ma. Diarey B.Symbiosis driven variation and supply of natural products2015-12dissertation
7 dela Cruz, Richard Glenn CuaAntithrombin III residue tyrosine-131 serves as a molecular switch during heparinmediated conformational activation of its anticoagulant activityPentasaccharide; Allosteric Activation; Mutants2006-05dissertation
8 Dang, TongyunExploring triterpene cyclization mechanism : binding sites mapping and mutagenesisAntimicrobial Agents; Catalytic2000-08dissertation
9 Qian, LianMolecular design and chemical synthesis of affinity probes for lysophosphatidic acid receptorsOvarian Neoplasms2004-05dissertation
10 Mitchell, Scott S.Structural investigations of metabolites from four marine invertebratesAscidian Didemnum Voeltzkowi; Conotoxin; Amphimedon Viridis1997-08dissertation
11 Donia, Mohamed Samir AbouBiosynthesis and genetic engineering of biologically active natural products from marine ascidian symbionts2010-08dissertation
12 Nair, VinodNuclear Magnetic resonance spectroscopy of escherichia coli tRNA (LYS) and the t RNA)LYS)-HIV RNA complexGenetics2007-05thesis
13 Sadat Hayatshahi, Sayyed HamedThe effect of atomistic interactions on RNA conformational distributions, folding and ligand binding via molecular dynamics simulations and docking2016dissertation
14 Nelson, James ThomasBiosynthesis of marine peptide natural productsPharmacokinetics; Chemical Synthesis2006-12thesis
15 Richardson, Adam DavidChemical and biological studies of secondary metabolites from Lissoclinum patellaSea Squits; Physiology; Marine Metabolites2003-08dissertation
16 Gregson, John MichaelMass spectrometry of nucleosides related to guanosine, and codicillary research topicsEnvironmental Research; Biomedical1994-06dissertation
17 Doyle, KellyOxidation of peroxiredoxins and carbonylation of class I histone deacetylases by arachidonic acid metabolitesCyclooxygenase; Cyclopentenone; Histone deacetylase; Lipoxygenase; Peroxiredoxin; Redox Biochemistry2010dissertation
18 Pomerantz, Steven C.Characterization of complex mixtures of isomeric oligonucleotides by electrospray ionization tendem mass spectrometryElectron Ionization; Tetramethylethylenediamine2002-08dissertation
19 Lazar, JosefElephant sex pheromone transport and recognitionPhysiology; Analysis2001-12dissertation
20 Kakule, Thomas ButanazibaEngineering combinatorial biosynthesis of polyketide synthase-pepide synthetase products using novel fungal genetic toolsGenetics; Biochemistry2015-05dissertation
21 Sardar, DebosmitaThe cyanobactin biosynthetic machinery: promiscuity, modularity and unique chemistry from the oceansBiochemistry2016dissertation
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