Theses & Dissertations
 
Filters: Department: "Medicinal Chemistry" Collection: "ir_etd" Type: "Text" Format: "application/pdf"
1 - 25 of 78
Number of results to display per page
AuthorTitleSubjectDatePublication Type
1 Bhalgat, Mahesh KantilalAntibody-directed delivery of copper-67 to tumorsMonoclonal Antibodies; Raiommunoconjugates1995-06dissertation
2 dela Cruz, Richard Glenn CuaAntithrombin III residue tyrosine-131 serves as a molecular switch during heparinmediated conformational activation of its anticoagulant activityPentasaccharide; Allosteric Activation; Mutants2006-05dissertation
3 Bi, YilingApplications of computational tools and biochemical approaches in elucidating biogenesis of antithrombin III bibduing heparan sulfate structures, defining xyloside-mediated glycosaminoglycan priming activity, and discovering drugs to treat human n-glycanase 1 (NGLYI) deficiency2019dissertation
4 Biskupiak, Joseph EdwardBioactive metabolites from marine organisms.Microbiology; Physiology; Biochemistry1985-06dissertation
5 McKee, Tawnya CarleneBioactive metabolites from marine organisms: the chemistry of Xestospongia Caycedoi, Diplosoma species Trididemnum solidum and the marine microbe Streptomyces speciesMicrobial Metabolites; Biochemistry1990-12dissertation
6 Cornillie, Sean PaulBiomolecular simulation protocols enabling effective peptide therapeutic design: model validation and optimizationPublic health; Physiology; Epidemiology; Biophysics2018dissertation
7 Donia, Mohamed Samir AbouBiosynthesis and genetic engineering of biologically active natural products from marine ascidian symbionts2010-08dissertation
8 Nelson, James ThomasBiosynthesis of marine peptide natural productsPharmacokinetics; Chemical Synthesis2006-12thesis
9 Ma, ShuangyuBuilding a research toolkit for protein tyrosine phosphatases2019dissertation
10 Pomerantz, Steven C.Characterization of complex mixtures of isomeric oligonucleotides by electrospray ionization tendem mass spectrometryElectron Ionization; Tetramethylethylenediamine2002-08dissertation
11 Swersey, J. ChristopherCharacterization of metabolites from three tropical Pacific marine invertebratesMamauthaquinone; Quinone Sesquiterpenoids1992-08thesis
12 Dominick, Pamela K.Chemical and biological analysis of novel thiazolidine prodrugs of L-cysteinePhysiology; Analysis; Prodrugs2002-05dissertation
13 Richardson, Adam DavidChemical and biological studies of secondary metabolites from Lissoclinum patellaSea Squits; Physiology; Marine Metabolites2003-08dissertation
14 Kulkarni, Rhushikkesh ArunChemical probes for lymphoid tyrosine phosphatase2013-12dissertation
15 Jiang, GuoweiChemical synthesis and biological evaluation of novel lysophospholipid analoguesgSynthesis; Lysophosphatidic Acid receptors2006-12thesis
16 Sha, JiangDesign, synthesis and evaluation of doxorubicin based anti-cancer drug conjugatesPharmacology2006-08thesis
17 Liu, Xiao-huiDidehydrogeranylgeraniol ([delta delta] GGOH) and anti-isoprenyl antibodies for protein prenylationAntagonists and Inhibitors2002-12dissertation
18 Mullally, James EdwardDiscovery of novel effectors of the proteasome pathway: cyclopentenones as inhibitors of ubiquitin isopeptidase activityNeoplasms; Drug Therapy2003-05dissertation
19 Sandoval, Imelda TumananDysregulation of retinoid biosynthesis and metabolism during colon carcinogenesisColon; Retinoids2006-05dissertation
20 Sundaram, MallikarjunEffect of modified nucleosides on the structure of the anticodon domain of Escherichia coli tRNALysEscherichia coli; tRNA(Lys), Nucleosides, Anticodon domain; Biochemistry2000-08dissertation
21 Lazar, JosefElephant sex pheromone transport and recognitionPhysiology; Analysis2001-12dissertation
22 McIntosh, John AndrewElucidation of cyanobactin biosynthesisBiochemistry2011-12dissertation
23 Kakule, Thomas ButanazibaEngineering combinatorial biosynthesis of polyketide synthase-pepide synthetase products using novel fungal genetic toolsGenetics; Biochemistry2015-05dissertation
24 Green, Brad ReedEngineering systemically bioavailable analogs of endogenous neuropeptidesNeurosciences; Biochemistry; Pharmacy sciences2010-12thesis
25 Dang, TongyunExploring triterpene cyclization mechanism : binding sites mapping and mutagenesisAntimicrobial Agents; Catalytic2000-08dissertation
1 - 25 of 78