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AuthorTitleSubjectDatePublication Type
1 Vaden, Rachel MelindaA chemical biology approach towards the development of strategies to target drug refractory breast cancerBreast cancer; chemical biology; chemoresistance; small molecule; zinc2015dissertation
2 Hoggard, Logan ReidDesign and synthesis of small-molecule inhibitors for B-Catenin/BCL9 protein-protein interactionsChemistry; Small molecules2014-12thesis
3 Terooatea, Tommy WInvestigating the role of the methyl-cpg binding protein zbtb33 in cancerCancer; ChIP-exo; Epigenetics; RNA-seq; ZBTB332017dissertation
4 Gao, ZhePreparation of bio-compatible boron nanoparticles and novel mesoporous silica nanoparticles for bio-applicationsbio-compatible nanoparticles; boron neutron capture therapy; degradable materials; mesoporous silica nanoparticles; silsesquioxane; tannic acid2013-05dissertation
5 Catrow, Jonathan LeonToward better development of protein-protein interaction inhibitors: applications to the β-catenin/t-cell factor protein-protein interactionPure sciences; Beta-catenin/t-cell; Catenin; Inhibitors; Protein; Protein-protein2017dissertation
6 Li, WeiThe synthetic and biological study of bryostatin analoguesBryostatin analogues; Bryostatins; Organic synthesis; Protein kinase C; Pyran annulation; Marine pharmacology; Bugula neritina2011-05dissertation
7 Peterson, Amberlyn MeganManipulating the electrostatic properties of nucleic acids for applications in sensing and drug deliveryAptamer; Gold Nanoparticles; Micelle; Nucleic Acids; Peptide Nucleic Acid; Surfactants2016dissertation
8 Huang, ZhengDesign and synthesis of selective inhibitors for β-catenin/t-cell factor-4 protein-protein interactionbeta-catenin; hot spot based design; peptidomimetics; Wnt signaling pathway2017dissertation
9 Teuscher, Kevin BruceCellular bioavailability of small-molecule inhibitors and optimization of small-molecule inhibitors for b-catenin mediation protein=protein interactions2018dissertation
10 Walton, Nathan IsaacSynthesis of internally functionalized silica nanoparticles for theranostic applicationsBoron; Mesoporous; Nanoparticle; Silica; Synthesis; Theranostic2013-08dissertation
11 Alenko, AntonDetection of products of guanine oxidation in RNABiochemistry2018dissertation
12 Ghanty, Uday8-alkoxyadenosines modulate RNA interference efficacy and off-pathway protein binding8-alkoxyadenosine; caspase 2 gene silencing; off-pathway protein binding; off-target effect; RNAi; SiRNA2012-12dissertation
13 Pathak, Tejaskumar PankajbhaiPalladium-catalyzed functionalization of alkenes to provide biologically relevant scaffoldsAlkene functionalization; Biological study; Difunctionalization; Enantioselective; Indole; Palladium; Biologically relevant scaffolds2011-12dissertation
14 An, NaSingle-molecule analysis of DNA abasic sites and the human telomeric G-quadruplex through the alpha-hemolysin ion channel18-crown-6; Abasic sites; DNA; G-quadruplex; Nanopore; telomere2012-12dissertation
15 Salvant, Justin MichaelDevelopment of N-ACYL-2-Aminoimadazole Zinc ionophores2019dissertation
16 Omaga, Carla AlvarezAnalysis of the effect of the G-QU adruplex fifth domain on DNA folding in response to oxideative and abasic lesions2018dissertation
17 Omaga, Carla AlvarezAnalysis of the effect of the G-Quadruplex fifth domain on DNA folding in response to oxidative and abasic lesionsChemistry2018dissertation
18 Wolna, Anna H.Single-molecule analysis of DNA cross-links using nanopore technologyAlpha-hemolysin; DNA cross-links; G-quadruplexes; Human telomere sequence; Nanopore; Thymine-dimer2014-12dissertation
19 Guo, WenxingHot Spot-Based design and synthesis of small molecule inhibitors for β-Catenin/T-cell factor 4 protein-protein interaction and hemiporphyrin-like N-ACYL 2-aminoimidazoles: chemistry, biology and zinc binding properties2019dissertation
20 Edwards, Anne VictoriaEfforts toward the synthesis of NA22598A1 and the investigation of its mechanism of actionChemistry; Organic chemistry2017dissertation
21 Alshykhly, Omar R.Formation and enzyme processing of 5-carboxamido- 5-formamido-2-iminohydantoin, a major oxidation product of guanine in DNABase excision repair; DNA damage; Fenton reaction; Guanine oxidation; Reactive oxygen species; X-ray2015dissertation
22 Ghude, PranjaliStructure-switching selex for selection of aptamers of damaged nucleosides and nucleobases 8-oxoguanine and spiroiminodihydantoin8-OXOGUANINE; DAMAGED NUCLEOSIDES; DNA APTAMER; NUCLEOBASES; SPIROIMINODIHYDANTOIN; STRUCTURE-SWITCHING SELEX2015-08dissertation
23 Cummins, Thomas JosephThe synthesis of the c-ring subunit of bryostatin 1, and the synthesis and biological evaluation of fluorescent bryostatin analogsBryostatin2015-08dissertation
24 Rudra, ArnabStudies on the effects of various functional groups on the northern hemisphere of bryostatin through synthesisChemistry; Biochemistry; Organic chemistry2014dissertation
25 De Costa, Narahenpitage Tilani SandamalaSynthesis of Hepatitis C virus RNA targeted therapeutics and studies towards the Epidithiodiketopiperazine Alkylation in ChaetominHepatitis C virus; RNA; Targeted therapeutics; Epidithiodiketopiperazine; Alkylation; Chaetomin2011-05thesis
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