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TitleDescriptionSubjectCollection
1 1.0 Biosynthesis of Steroid Hormones - IntroductionA video introduction to the biosynthesis of steroid hormones. Guide questions -- What types of compounds are included in the class of steroids? Why is it important to know the sources and pathways in the synthesis of steroid hormones? University of Cincinnati College of Medicine Reproductive Phys...Biosynthesis; Hormone Deficiency; Steroid Hormones; Excess; PathwaysHEAL Reviewed Collection
2 Propionyl CoA carboxylase reactionPropionyl CoA is metabolized by a process that first converts it to D-methylmalonyl CoA. The reaction is catalyzed by propionyl CoA carboxylase,and requires energy in the form of ATP.BiosynthesisKnowledge Weavers Fatty Acids
3 Complete oxidation of an odd-chain fatty acid -- overviewThis diagram indicates production of propionyl CoA from an odd-chain fatty acid and the subsequent conversion of propionyl CoA to succinyl CoA, which can be metabolized through the citric (tricarboxylic) acid cycle.BiosynthesisKnowledge Weavers Fatty Acids
4 Fatty acid metabolism -- schematic overviewFatty acids are taken up by cells, where thy may serve as precursors in the synthesis of other compounds, as fuels for energy production, and as substrates for ketone body synthesis. Ketones bodies may then be exported to other tissues, where they can be used for energy production.BiosynthesisKnowledge Weavers Fatty Acids
5 Propionyl CoA production from odd-chain fatty acidsBeta-oxidation of fatty acids with an odd number of carbons inthe chain yields the three-carbon propionyl CoA as the final fragment.BiosynthesisKnowledge Weavers Fatty Acids
6 Hydroxymethylglutaryl CoA synthase reactionThis irreversible reaction occurs in the mitochondria, where it is the first step in ketone body synthesis. It also occurs in the cytoplasm, where it leads to isoprenoid and steroid synthesis.BiosynthesisKnowledge Weavers Fatty Acids
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