Theses & Dissertations
 
Filters: Department: "Medicinal Chemistry" Collection: "ir_etd"
1 - 25 of 78
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AuthorTitleSubjectDatePublication Type
1 Bhalgat, Mahesh KantilalAntibody-directed delivery of copper-67 to tumorsMonoclonal Antibodies; Raiommunoconjugates1995-06dissertation
2 dela Cruz, Richard Glenn CuaAntithrombin III residue tyrosine-131 serves as a molecular switch during heparinmediated conformational activation of its anticoagulant activityPentasaccharide; Allosteric Activation; Mutants2006-05dissertation
3 Bi, YilingApplications of computational tools and biochemical approaches in elucidating biogenesis of antithrombin III binding heparan sulfate structures, defining Xyloside-mediated glycosaminoglycan priming activity, and discovering drugs to treat human N-Glycanase 1 (NGLYI) deficiencyGlycosaminoglycan; N-glycanase 1; xyloside2019dissertation
4 Biskupiak, Joseph EdwardBioactive metabolites from marine organisms.Microbiology; Physiology; Biochemistry1985-06dissertation
5 McKee, Tawnya CarleneBioactive metabolites from marine organisms: the chemistry of Xestospongia Caycedoi, Diplosoma species Trididemnum solidum and the marine microbe Streptomyces speciesMicrobial Metabolites; Biochemistry1990-12dissertation
6 Cornillie, Sean PaulBiomolecular simulation protocols enabling effective peptide therapeutic design: model validation and optimizationPublic health; Physiology; Epidemiology; Biophysics2018dissertation
7 Donia, Mohamed Samir AbouBiosynthesis and genetic engineering of biologically active natural products from marine ascidian symbionts2010-08dissertation
8 Nelson, James ThomasBiosynthesis of marine peptide natural productsPharmacokinetics; Chemical Synthesis2006-12thesis
9 Ma, ShuangyuBuilding a research toolkit for protein tyrosine phosphatases2019dissertation
10 Pomerantz, Steven C.Characterization of complex mixtures of isomeric oligonucleotides by electrospray ionization tendem mass spectrometryElectron Ionization; Tetramethylethylenediamine2002-08dissertation
11 Zabriskie, T. MarkThe Characterization of cytotoxic metabolites from Fijian marine invertebratesPeptides, Cyclic; Porifera; Thiazoles; Urochordata1989-12dissertation
12 Swersey, J. ChristopherCharacterization of metabolites from three tropical Pacific marine invertebratesMamauthaquinone; Quinone Sesquiterpenoids1992-08thesis
13 Dominick, Pamela K.Chemical and biological analysis of novel thiazolidine prodrugs of L-cysteinePhysiology; Analysis; Prodrugs2002-05dissertation
14 Richardson, Adam DavidChemical and biological studies of secondary metabolites from Lissoclinum patellaSea Squits; Physiology; Marine Metabolites2003-08dissertation
15 Kulkarni, Rhushikkesh ArunChemical probes for lymphoid tyrosine phosphatase2013-12dissertation
16 Jiang, GuoweiChemical synthesis and biological evaluation of novel lysophospholipid analoguesgSynthesis; Lysophosphatidic Acid receptors2006-12thesis
17 Sardar, DebosmitaThe cyanobactin biosynthetic machinery: promiscuity, modularity and unique chemistry from the oceansBiochemistry2016dissertation
18 Sha, JiangDesign, synthesis and evaluation of doxorubicin based anti-cancer drug conjugatesPharmacology2006-08thesis
19 Liu, Xiao-huiDidehydrogeranylgeraniol ([delta delta] GGOH) and anti-isoprenyl antibodies for protein prenylationAntagonists and Inhibitors2002-12dissertation
20 Mullally, James EdwardDiscovery of novel effectors of the proteasome pathway: cyclopentenones as inhibitors of ubiquitin isopeptidase activityNeoplasms; Drug Therapy2003-05dissertation
21 Sandoval, Imelda TumananDysregulation of retinoid biosynthesis and metabolism during colon carcinogenesisColon; Retinoids2006-05dissertation
22 Sadat Hayatshahi, Sayyed HamedThe effect of atomistic interactions on RNA conformational distributions, folding and ligand binding via molecular dynamics simulations and docking2016dissertation
23 Sundaram, MallikarjunEffect of modified nucleosides on the structure of the anticodon domain of Escherichia coli tRNALysEscherichia coli; tRNA(Lys), Nucleosides, Anticodon domain; Biochemistry2000-08dissertation
24 Lazar, JosefElephant sex pheromone transport and recognitionPhysiology; Analysis2001-12dissertation
25 McIntosh, John AndrewElucidation of cyanobactin biosynthesisBiochemistry2011-12dissertation
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